Genetic control of two electrophoretic variants of glucosephosphate isomerase in the mouse (Mus musculus) View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1969-04

AUTHORS

Robert J. DeLorenzo, Frank H. Ruddle

ABSTRACT

The autosomal variation and the genetic control of GPI has been determined by a comparison of electrophoretic patterns of F1 and backcross progeny of three inbred strains of mice. The locus controlling the production of GPI in the mouse has been designated Gpi-1. Two alleles at this locus have been described and designated Gpi-1a and Gpi-1b, which represent, respectively, the slow and fast electrophoretic forms. Twenty-seven inbred strains of mice have been classified for these two alleles. The absence of close linkage of Gpi-1 to seven other genetic loci has been determined. It has been demonstrated that the polymorphism of Gpi-1 is widely distributed in feral mice. GPI was expressed in vitro and in four types of malignant tumors. More... »

PAGES

151-162

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00520350

DOI

http://dx.doi.org/10.1007/bf00520350

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1001088381

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/5364923


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