Hybridization of somatic cells derived from mouse and Syrian hamster: Evolution of karyotype and enzyme studies View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1968-03

AUTHORS

Barbara Ruben Migeon

ABSTRACT

Somatic hybrids of drug-resistant mutant hamster and mouse cell lines have been isolated and propagated in long-term culture and have been studied in respect to karyotype and three enzymes. During the course of propagation the long-surviving hybrid clones show progressive loss of telocentric chromosomes associated in at least one case with loss of mouse enzyme. Hybrid clones showed hybrid molecules for malate dehydrogenase (MDH), lactate dehydrogenase (LDH), and 6-phosphogluconate dehydrogenase (6PGD) made up by recombination of parental subunits. More... »

PAGES

305-322

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00491487

DOI

http://dx.doi.org/10.1007/bf00491487

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009978641

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/5717663


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