Evidence for X linkage of the mouse tear protein system-3 (Mtp-3) with mosaic expression in heterozygous females View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1984-06

AUTHORS

Y. Matsushima, T. Imai, S. Ikemoto

ABSTRACT

Electrophoretic variations exhibited by some tear proteins have been observed using 20 strains of mice. Fifteen to twenty protein components were detected in tears, and one of the proteins, designated Mtp-3 (mouse tear protein system-3), is found only in the NZB strain. NZB animals were crossed to BALB/c animals with no Mtp-3 and the results showed that Mtp-3 was controlled by a pair of alleles on the X chromosome. Mosaic expression was detected in females heterozygous for the Mtp-3 alleles when tear samples were examined separately from the right or left eye. This report supports Lyon's hypothesis and shows that mouse tears are useful for genetic research. More... »

PAGES

577-585

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00484524

DOI

http://dx.doi.org/10.1007/bf00484524

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1026019316

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6466292


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