A new bacterial gene (groPC) which affects λ DNA replication View Full Text


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Article Info

DATE

1977-01

AUTHORS

C. P. Georgopoulos

ABSTRACT

A bacterial mutation affecting λ DNA replication, called groPC756, has been mapped between the thr and leu bacterial loci. Most of the parental λ DNA does not undergo even one round of replication in this host. Lambda mutants, called π, which map in the λ P gene are able to overcome the inhibitory effect of the groPC756 mutation. It is shown that the mutation at the groPC locus also interferes with bacterial growth at 42°C. A λ-transducing phage, carrying the groPC+ allele, was isolated as a plaqueformer on groPC756 bacteria. Upon lysogenization, it restores both the gro+ and temperature resistant phenotypes. More... »

PAGES

35-39

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00446910

DOI

http://dx.doi.org/10.1007/bf00446910

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024210607

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/325365


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