Prevalence of coeliac disease in diabetic children and adolescents View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1988-11

AUTHORS

S. Koletzko, A. Bürgin-Wolff, B. Koletzko, M. Knapp, W. Burger, D. Grüneklee, G. Herz, W. Ruch, A. Thon, U. Wendel, K. Zuppinger

ABSTRACT

Screening for coeliac disease (CD) with serum antigliadin antibodies (AGA) was performed in 1032 diabetic children and adolescents. In 8 children CD had been diagnosed before study entry. Of the remaining 1024 children, 33 had an elevated AGA titre in the first serum sample. On follow-up an elevated AGA titre was confirmed in only 17 of 31 patients. Nine of the repeatedly positive patients underwent jejunal biopsy, and CD was diagnosed in two asymptomatic patients; both were positive for IgG- and IgA-AGA. Among 10 AGA-positive patients in whom biopsies could not be performed, only 1 showed IgA-AGA and thus carried a high risk for CD. From our results we estimate a prevalence of CD in Swiss and German diabetic children between 1.1% and 1.3%. False-positive AGA titres occurred significantly more often in patients with diabetes duration of less than 1 year. AGA testing reached a specificity of 99% if performed at least 1 year after the onset of diabetes. Children suffering from both diabetes and CD showed a diabetes manifestation at a significantly younger age than non-coeliac patients, whereas CD tended to be diagnosed at a remarkably late age. More... »

PAGES

113-117

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00445915

DOI

http://dx.doi.org/10.1007/bf00445915

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039432257

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3069470


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adolescent", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Biopsy", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Celiac Disease", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Child", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diabetes Mellitus, Type 1", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "False Negative Reactions", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "False Positive Reactions", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gliadin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunoglobulin A", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunoglobulin G", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Multicenter Studies as Topic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sex Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "D\u00fcsseldorf University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.14778.3d", 
          "name": [
            "Universit\u00e4ts-Kinderklinik, Moorenstrasse 5, D-4000, D\u00fcsseldorf 1, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Koletzko", 
        "givenName": "S.", 
        "id": "sg:person.0716700160.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716700160.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Kinderklinik der Universit\u00e4t, Basel, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "B\u00fcrgin-Wolff", 
        "givenName": "A.", 
        "id": "sg:person.074565476.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.074565476.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "D\u00fcsseldorf University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.14778.3d", 
          "name": [
            "Universit\u00e4ts-Kinderklinik, Moorenstrasse 5, D-4000, D\u00fcsseldorf 1, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Koletzko", 
        "givenName": "B.", 
        "id": "sg:person.01204766151.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204766151.62"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Institut f\u00fcr Medizinische Statistik und Biomathematik, D\u00fcsseldorf, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Knapp", 
        "givenName": "M.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Kinderklinik der Universit\u00e4t, Berlin, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Burger", 
        "givenName": "W.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Diabetes-Forschungsinstitut an der Universit\u00e4t, D\u00fcsseldorf, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gr\u00fcneklee", 
        "givenName": "D.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Kinderklinik der Universit\u00e4t, Berlin, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Herz", 
        "givenName": "G.", 
        "id": "sg:person.01156205463.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156205463.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Kinderklinik der Universit\u00e4t, Basel, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ruch", 
        "givenName": "W.", 
        "id": "sg:person.01227301243.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227301243.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Kinderklinik der Universit\u00e4t, Ulm, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Thon", 
        "givenName": "A.", 
        "id": "sg:person.01116406335.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01116406335.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "D\u00fcsseldorf University Hospital", 
          "id": "https://www.grid.ac/institutes/grid.14778.3d", 
          "name": [
            "Universit\u00e4ts-Kinderklinik, Moorenstrasse 5, D-4000, D\u00fcsseldorf 1, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wendel", 
        "givenName": "U.", 
        "id": "sg:person.01113337735.66", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113337735.66"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Kinderklinik der Universit\u00e4t, Bern, Switzerland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Zuppinger", 
        "givenName": "K.", 
        "id": "sg:person.073436272.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.073436272.71"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1111/j.1651-2227.1981.tb16568.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001583988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(69)90363-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007560879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.164.1.333", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008093913"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00491938", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010396759", 
          "https://doi.org/10.1007/bf00491938"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00491938", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010396759", 
          "https://doi.org/10.1007/bf00491938"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005176-198609000-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013406967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005176-198609000-00010", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013406967"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-065x.1983.tb00715.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015128031"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(86)81042-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015742729"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/adc.54.10.783", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017587449"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.160.5.1544", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019002013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(69)91817-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020656319"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(69)91817-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020656319"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.26.7.667", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025812796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(69)92512-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029568910"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(69)92512-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029568910"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(69)92201-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031269514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(69)92201-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031269514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/adc.62.5.469", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031465746"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005176-198510000-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031497278"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005176-198510000-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031497278"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/adc.50.2.162", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031642446"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/pgmj.50.579.45", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033405664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/pgmj.50.579.45", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033405664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/adc.59.8.739", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035012725"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.82.20.6970", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040100027"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/00365528509089626", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043021015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1651-2227.1987.tb10542.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044317741"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(87)92357-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045681455"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(74)80462-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046164963"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(83)80229-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048563203"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-3476(82)80018-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049999381"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diab.18.12.858", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070731602"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diab.27.11.1092", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070733212"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diabetes.27.11.1092", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070739524"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079802967", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079916220", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080010720", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080456288", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081567663", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081935275", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081941127", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082117284", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082186260", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082350971", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082361131", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082591787", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082916418", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1988-11", 
    "datePublishedReg": "1988-11-01", 
    "description": "Screening for coeliac disease (CD) with serum antigliadin antibodies (AGA) was performed in 1032 diabetic children and adolescents. In 8 children CD had been diagnosed before study entry. Of the remaining 1024 children, 33 had an elevated AGA titre in the first serum sample. On follow-up an elevated AGA titre was confirmed in only 17 of 31 patients. Nine of the repeatedly positive patients underwent jejunal biopsy, and CD was diagnosed in two asymptomatic patients; both were positive for IgG- and IgA-AGA. Among 10 AGA-positive patients in whom biopsies could not be performed, only 1 showed IgA-AGA and thus carried a high risk for CD. From our results we estimate a prevalence of CD in Swiss and German diabetic children between 1.1% and 1.3%. False-positive AGA titres occurred significantly more often in patients with diabetes duration of less than 1 year. AGA testing reached a specificity of 99% if performed at least 1 year after the onset of diabetes. Children suffering from both diabetes and CD showed a diabetes manifestation at a significantly younger age than non-coeliac patients, whereas CD tended to be diagnosed at a remarkably late age.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf00445915", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1017354", 
        "issn": [
          "0340-6199", 
          "1432-1076"
        ], 
        "name": "European Journal of Pediatrics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "2", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "148"
      }
    ], 
    "name": "Prevalence of coeliac disease in diabetic children and adolescents", 
    "pagination": "113-117", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "bbd645112f93443cbfc0cd1b0dbe5b61ffd58cdf54ce67b9e4cbe6f173a83808"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "3069470"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "7603873"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf00445915"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1039432257"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf00445915", 
      "https://app.dimensions.ai/details/publication/pub.1039432257"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T14:02", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000371_0000000371/records_130831_00000003.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF00445915"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00445915'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00445915'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00445915'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00445915'


 

This table displays all metadata directly associated to this object as RDF triples.

323 TRIPLES      21 PREDICATES      85 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf00445915 schema:about N2345305c7b7947ce8f25460ac1ea9418
2 N26ed4f14e5134737a2aab4947b8412b9
3 N35efc18c99334f2182a3a54190a9af8d
4 N3d25a6645aea4227923bf6feb1db8efa
5 N5641ccc1c0f24ff4908fc25644a86289
6 N570fd2c69d2a499ead91a71bb10f19c1
7 N5a7648775a284214a6c98f2ca58d3360
8 N656d312eae3c4737b5cf558fe5da7fab
9 N66177ee02c2843a4ae1eefccb40a82c0
10 N74cb22d589e34f368c7c41af92399a33
11 N818e4c9202934edeb997cabdadcf0f10
12 N933c56383a81448e97d1cdc52551188b
13 Nb3a70208a79046c098f926f5711c80b4
14 Neab16581012b414bb19ffff12671926d
15 Nf516b97329f14fdf975c03bae3e5e9d9
16 anzsrc-for:11
17 anzsrc-for:1103
18 schema:author N59605694f91d403fbdcdc696d12cf829
19 schema:citation sg:pub.10.1007/bf00491938
20 https://app.dimensions.ai/details/publication/pub.1079802967
21 https://app.dimensions.ai/details/publication/pub.1079916220
22 https://app.dimensions.ai/details/publication/pub.1080010720
23 https://app.dimensions.ai/details/publication/pub.1080456288
24 https://app.dimensions.ai/details/publication/pub.1081567663
25 https://app.dimensions.ai/details/publication/pub.1081935275
26 https://app.dimensions.ai/details/publication/pub.1081941127
27 https://app.dimensions.ai/details/publication/pub.1082117284
28 https://app.dimensions.ai/details/publication/pub.1082186260
29 https://app.dimensions.ai/details/publication/pub.1082350971
30 https://app.dimensions.ai/details/publication/pub.1082361131
31 https://app.dimensions.ai/details/publication/pub.1082591787
32 https://app.dimensions.ai/details/publication/pub.1082916418
33 https://doi.org/10.1016/s0022-3476(74)80462-2
34 https://doi.org/10.1016/s0022-3476(82)80018-8
35 https://doi.org/10.1016/s0022-3476(83)80229-7
36 https://doi.org/10.1016/s0022-3476(86)81042-3
37 https://doi.org/10.1016/s0140-6736(69)90363-8
38 https://doi.org/10.1016/s0140-6736(69)91817-0
39 https://doi.org/10.1016/s0140-6736(69)92201-6
40 https://doi.org/10.1016/s0140-6736(69)92512-4
41 https://doi.org/10.1016/s0140-6736(87)92357-9
42 https://doi.org/10.1073/pnas.82.20.6970
43 https://doi.org/10.1084/jem.160.5.1544
44 https://doi.org/10.1084/jem.164.1.333
45 https://doi.org/10.1097/00005176-198510000-00007
46 https://doi.org/10.1097/00005176-198609000-00010
47 https://doi.org/10.1111/j.1600-065x.1983.tb00715.x
48 https://doi.org/10.1111/j.1651-2227.1981.tb16568.x
49 https://doi.org/10.1111/j.1651-2227.1987.tb10542.x
50 https://doi.org/10.1136/adc.50.2.162
51 https://doi.org/10.1136/adc.54.10.783
52 https://doi.org/10.1136/adc.59.8.739
53 https://doi.org/10.1136/adc.62.5.469
54 https://doi.org/10.1136/gut.26.7.667
55 https://doi.org/10.1136/pgmj.50.579.45
56 https://doi.org/10.2337/diab.18.12.858
57 https://doi.org/10.2337/diab.27.11.1092
58 https://doi.org/10.2337/diabetes.27.11.1092
59 https://doi.org/10.3109/00365528509089626
60 schema:datePublished 1988-11
61 schema:datePublishedReg 1988-11-01
62 schema:description Screening for coeliac disease (CD) with serum antigliadin antibodies (AGA) was performed in 1032 diabetic children and adolescents. In 8 children CD had been diagnosed before study entry. Of the remaining 1024 children, 33 had an elevated AGA titre in the first serum sample. On follow-up an elevated AGA titre was confirmed in only 17 of 31 patients. Nine of the repeatedly positive patients underwent jejunal biopsy, and CD was diagnosed in two asymptomatic patients; both were positive for IgG- and IgA-AGA. Among 10 AGA-positive patients in whom biopsies could not be performed, only 1 showed IgA-AGA and thus carried a high risk for CD. From our results we estimate a prevalence of CD in Swiss and German diabetic children between 1.1% and 1.3%. False-positive AGA titres occurred significantly more often in patients with diabetes duration of less than 1 year. AGA testing reached a specificity of 99% if performed at least 1 year after the onset of diabetes. Children suffering from both diabetes and CD showed a diabetes manifestation at a significantly younger age than non-coeliac patients, whereas CD tended to be diagnosed at a remarkably late age.
63 schema:genre research_article
64 schema:inLanguage en
65 schema:isAccessibleForFree false
66 schema:isPartOf Ne2cfd2ba3df1470c952e4641d27d6715
67 Ne4edcac40d38482fa3a7818f670e60bf
68 sg:journal.1017354
69 schema:name Prevalence of coeliac disease in diabetic children and adolescents
70 schema:pagination 113-117
71 schema:productId N733db4e7f13c4608a4eeec4b7a21fc60
72 Naacedc66aa3b4fa3bf1a7273bc29c744
73 Nc324d0fb9b5d4207985a23a07b350df4
74 Nf3eb5564f5454477ae2f3b1f42bd449c
75 Nf94efd0e74664e9a8a010e40d8ab1eb2
76 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039432257
77 https://doi.org/10.1007/bf00445915
78 schema:sdDatePublished 2019-04-11T14:02
79 schema:sdLicense https://scigraph.springernature.com/explorer/license/
80 schema:sdPublisher N2b158c458c364fcdb32101958b6efdab
81 schema:url http://link.springer.com/10.1007/BF00445915
82 sgo:license sg:explorer/license/
83 sgo:sdDataset articles
84 rdf:type schema:ScholarlyArticle
85 N11da2bb369ff4d5c8642c64728c071ed rdf:first sg:person.01227301243.20
86 rdf:rest N6921cd88d2444527b17fcf4d58fb2ac9
87 N1a7b2d733bb14cba91fa2ab84ae62eb1 rdf:first sg:person.01204766151.62
88 rdf:rest N7bdc57e527b54bf2999e78f3839ba223
89 N22d68cc6ff8b4e3881d5ff18ccd22925 rdf:first sg:person.073436272.71
90 rdf:rest rdf:nil
91 N2345305c7b7947ce8f25460ac1ea9418 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name False Positive Reactions
93 rdf:type schema:DefinedTerm
94 N26ed4f14e5134737a2aab4947b8412b9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Sex Factors
96 rdf:type schema:DefinedTerm
97 N2b158c458c364fcdb32101958b6efdab schema:name Springer Nature - SN SciGraph project
98 rdf:type schema:Organization
99 N35efc18c99334f2182a3a54190a9af8d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name False Negative Reactions
101 rdf:type schema:DefinedTerm
102 N3d25a6645aea4227923bf6feb1db8efa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Male
104 rdf:type schema:DefinedTerm
105 N45cc5dfed2c64f57a04fab59e8c2990d rdf:first Ne9b9ec38a61d4452b1a076a2149ef06a
106 rdf:rest Ndcc3fa2beef54c8bb33dd496b141cccc
107 N47b8724ade5b4991adcc254038024f14 schema:name Kinderklinik der Universität, Berlin, Federal Republic of Germany
108 rdf:type schema:Organization
109 N54c5caa838b84b70b2a42dede2072ae1 schema:name Kinderklinik der Universität, Berlin, Federal Republic of Germany
110 rdf:type schema:Organization
111 N5641ccc1c0f24ff4908fc25644a86289 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Gliadin
113 rdf:type schema:DefinedTerm
114 N570fd2c69d2a499ead91a71bb10f19c1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Diabetes Mellitus, Type 1
116 rdf:type schema:DefinedTerm
117 N59605694f91d403fbdcdc696d12cf829 rdf:first sg:person.0716700160.68
118 rdf:rest Na714fb389f724edc94d55a6a7f2f85c3
119 N5a7648775a284214a6c98f2ca58d3360 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Celiac Disease
121 rdf:type schema:DefinedTerm
122 N6297700b3b614db7a6d18e9621a90cd5 schema:name Diabetes-Forschungsinstitut an der Universität, Düsseldorf, Federal Republic of Germany
123 rdf:type schema:Organization
124 N656d312eae3c4737b5cf558fe5da7fab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Immunoglobulin G
126 rdf:type schema:DefinedTerm
127 N66177ee02c2843a4ae1eefccb40a82c0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Child
129 rdf:type schema:DefinedTerm
130 N6921cd88d2444527b17fcf4d58fb2ac9 rdf:first sg:person.01116406335.19
131 rdf:rest Ne8fc05f131d04ac4854527725cb6e29d
132 N733db4e7f13c4608a4eeec4b7a21fc60 schema:name readcube_id
133 schema:value bbd645112f93443cbfc0cd1b0dbe5b61ffd58cdf54ce67b9e4cbe6f173a83808
134 rdf:type schema:PropertyValue
135 N74cb22d589e34f368c7c41af92399a33 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Immunoglobulin A
137 rdf:type schema:DefinedTerm
138 N75a0b0e453654cf6b1d5658a2931584f schema:name Kinderklinik der Universität, Bern, Switzerland
139 rdf:type schema:Organization
140 N7bdc57e527b54bf2999e78f3839ba223 rdf:first N7e719e1d752f46ca81f45e857e7177fc
141 rdf:rest N9e337115e0bf453ebff6f4083fea9fa9
142 N7e719e1d752f46ca81f45e857e7177fc schema:affiliation Nfeae63599c254eb88e08471b2907946d
143 schema:familyName Knapp
144 schema:givenName M.
145 rdf:type schema:Person
146 N818e4c9202934edeb997cabdadcf0f10 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Multicenter Studies as Topic
148 rdf:type schema:DefinedTerm
149 N933c56383a81448e97d1cdc52551188b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Female
151 rdf:type schema:DefinedTerm
152 N9e337115e0bf453ebff6f4083fea9fa9 rdf:first Nfdd6c97a64ff4d46ab0be8df4089eb82
153 rdf:rest N45cc5dfed2c64f57a04fab59e8c2990d
154 Na714fb389f724edc94d55a6a7f2f85c3 rdf:first sg:person.074565476.44
155 rdf:rest N1a7b2d733bb14cba91fa2ab84ae62eb1
156 Na80e94b3694a49f5bdc573665ab825b3 schema:name Kinderklinik der Universität, Ulm, Federal Republic of Germany
157 rdf:type schema:Organization
158 Naacedc66aa3b4fa3bf1a7273bc29c744 schema:name pubmed_id
159 schema:value 3069470
160 rdf:type schema:PropertyValue
161 Nb3a70208a79046c098f926f5711c80b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Humans
163 rdf:type schema:DefinedTerm
164 Nb9fd35eb1fed4277afd9b63244eb7d60 schema:name Kinderklinik der Universität, Basel, Switzerland
165 rdf:type schema:Organization
166 Nc324d0fb9b5d4207985a23a07b350df4 schema:name dimensions_id
167 schema:value pub.1039432257
168 rdf:type schema:PropertyValue
169 Nd140e24f4aea459387e55ef97eff46c5 schema:name Kinderklinik der Universität, Basel, Switzerland
170 rdf:type schema:Organization
171 Ndcc3fa2beef54c8bb33dd496b141cccc rdf:first sg:person.01156205463.29
172 rdf:rest N11da2bb369ff4d5c8642c64728c071ed
173 Ne2cfd2ba3df1470c952e4641d27d6715 schema:volumeNumber 148
174 rdf:type schema:PublicationVolume
175 Ne4edcac40d38482fa3a7818f670e60bf schema:issueNumber 2
176 rdf:type schema:PublicationIssue
177 Ne8fc05f131d04ac4854527725cb6e29d rdf:first sg:person.01113337735.66
178 rdf:rest N22d68cc6ff8b4e3881d5ff18ccd22925
179 Ne9b9ec38a61d4452b1a076a2149ef06a schema:affiliation N6297700b3b614db7a6d18e9621a90cd5
180 schema:familyName Grüneklee
181 schema:givenName D.
182 rdf:type schema:Person
183 Neab16581012b414bb19ffff12671926d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
184 schema:name Adolescent
185 rdf:type schema:DefinedTerm
186 Nf3eb5564f5454477ae2f3b1f42bd449c schema:name nlm_unique_id
187 schema:value 7603873
188 rdf:type schema:PropertyValue
189 Nf516b97329f14fdf975c03bae3e5e9d9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
190 schema:name Biopsy
191 rdf:type schema:DefinedTerm
192 Nf94efd0e74664e9a8a010e40d8ab1eb2 schema:name doi
193 schema:value 10.1007/bf00445915
194 rdf:type schema:PropertyValue
195 Nfdd6c97a64ff4d46ab0be8df4089eb82 schema:affiliation N47b8724ade5b4991adcc254038024f14
196 schema:familyName Burger
197 schema:givenName W.
198 rdf:type schema:Person
199 Nfeae63599c254eb88e08471b2907946d schema:name Institut für Medizinische Statistik und Biomathematik, Düsseldorf, Federal Republic of Germany
200 rdf:type schema:Organization
201 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
202 schema:name Medical and Health Sciences
203 rdf:type schema:DefinedTerm
204 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
205 schema:name Clinical Sciences
206 rdf:type schema:DefinedTerm
207 sg:journal.1017354 schema:issn 0340-6199
208 1432-1076
209 schema:name European Journal of Pediatrics
210 rdf:type schema:Periodical
211 sg:person.01113337735.66 schema:affiliation https://www.grid.ac/institutes/grid.14778.3d
212 schema:familyName Wendel
213 schema:givenName U.
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01113337735.66
215 rdf:type schema:Person
216 sg:person.01116406335.19 schema:affiliation Na80e94b3694a49f5bdc573665ab825b3
217 schema:familyName Thon
218 schema:givenName A.
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01116406335.19
220 rdf:type schema:Person
221 sg:person.01156205463.29 schema:affiliation N54c5caa838b84b70b2a42dede2072ae1
222 schema:familyName Herz
223 schema:givenName G.
224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156205463.29
225 rdf:type schema:Person
226 sg:person.01204766151.62 schema:affiliation https://www.grid.ac/institutes/grid.14778.3d
227 schema:familyName Koletzko
228 schema:givenName B.
229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01204766151.62
230 rdf:type schema:Person
231 sg:person.01227301243.20 schema:affiliation Nd140e24f4aea459387e55ef97eff46c5
232 schema:familyName Ruch
233 schema:givenName W.
234 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01227301243.20
235 rdf:type schema:Person
236 sg:person.0716700160.68 schema:affiliation https://www.grid.ac/institutes/grid.14778.3d
237 schema:familyName Koletzko
238 schema:givenName S.
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0716700160.68
240 rdf:type schema:Person
241 sg:person.073436272.71 schema:affiliation N75a0b0e453654cf6b1d5658a2931584f
242 schema:familyName Zuppinger
243 schema:givenName K.
244 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.073436272.71
245 rdf:type schema:Person
246 sg:person.074565476.44 schema:affiliation Nb9fd35eb1fed4277afd9b63244eb7d60
247 schema:familyName Bürgin-Wolff
248 schema:givenName A.
249 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.074565476.44
250 rdf:type schema:Person
251 sg:pub.10.1007/bf00491938 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010396759
252 https://doi.org/10.1007/bf00491938
253 rdf:type schema:CreativeWork
254 https://app.dimensions.ai/details/publication/pub.1079802967 schema:CreativeWork
255 https://app.dimensions.ai/details/publication/pub.1079916220 schema:CreativeWork
256 https://app.dimensions.ai/details/publication/pub.1080010720 schema:CreativeWork
257 https://app.dimensions.ai/details/publication/pub.1080456288 schema:CreativeWork
258 https://app.dimensions.ai/details/publication/pub.1081567663 schema:CreativeWork
259 https://app.dimensions.ai/details/publication/pub.1081935275 schema:CreativeWork
260 https://app.dimensions.ai/details/publication/pub.1081941127 schema:CreativeWork
261 https://app.dimensions.ai/details/publication/pub.1082117284 schema:CreativeWork
262 https://app.dimensions.ai/details/publication/pub.1082186260 schema:CreativeWork
263 https://app.dimensions.ai/details/publication/pub.1082350971 schema:CreativeWork
264 https://app.dimensions.ai/details/publication/pub.1082361131 schema:CreativeWork
265 https://app.dimensions.ai/details/publication/pub.1082591787 schema:CreativeWork
266 https://app.dimensions.ai/details/publication/pub.1082916418 schema:CreativeWork
267 https://doi.org/10.1016/s0022-3476(74)80462-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046164963
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1016/s0022-3476(82)80018-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049999381
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1016/s0022-3476(83)80229-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048563203
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1016/s0022-3476(86)81042-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015742729
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1016/s0140-6736(69)90363-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007560879
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1016/s0140-6736(69)91817-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020656319
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1016/s0140-6736(69)92201-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031269514
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1016/s0140-6736(69)92512-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029568910
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1016/s0140-6736(87)92357-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045681455
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1073/pnas.82.20.6970 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040100027
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1084/jem.160.5.1544 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019002013
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1084/jem.164.1.333 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008093913
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1097/00005176-198510000-00007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031497278
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1097/00005176-198609000-00010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013406967
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1111/j.1600-065x.1983.tb00715.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1015128031
296 rdf:type schema:CreativeWork
297 https://doi.org/10.1111/j.1651-2227.1981.tb16568.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001583988
298 rdf:type schema:CreativeWork
299 https://doi.org/10.1111/j.1651-2227.1987.tb10542.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1044317741
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1136/adc.50.2.162 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031642446
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1136/adc.54.10.783 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017587449
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1136/adc.59.8.739 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035012725
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1136/adc.62.5.469 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031465746
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1136/gut.26.7.667 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025812796
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1136/pgmj.50.579.45 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033405664
312 rdf:type schema:CreativeWork
313 https://doi.org/10.2337/diab.18.12.858 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070731602
314 rdf:type schema:CreativeWork
315 https://doi.org/10.2337/diab.27.11.1092 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070733212
316 rdf:type schema:CreativeWork
317 https://doi.org/10.2337/diabetes.27.11.1092 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070739524
318 rdf:type schema:CreativeWork
319 https://doi.org/10.3109/00365528509089626 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043021015
320 rdf:type schema:CreativeWork
321 https://www.grid.ac/institutes/grid.14778.3d schema:alternateName Düsseldorf University Hospital
322 schema:name Universitäts-Kinderklinik, Moorenstrasse 5, D-4000, Düsseldorf 1, Federal Republic of Germany
323 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...