Neonatal renal dysfunction and intrauterine exposure to prostaglandin synthesis inhibitors View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1989-01

AUTHORS

U. Simeoni, J. Messer, P. Weisburd, J. Haddad, D. Willard

ABSTRACT

Three cases of renal dysfunction at birth were observed in premature babies exposed in utero to prostaglandin synthetase inhibitors (PSI) and corticosteroids. Transient water and sodium retention with uraemia occurred in one patient, and severe acute renal failure with marked hyperkalaemia in twins. These findings may be due to impairment of prostaglandin (PG)-mediated renal adaptation to stress conditions after transplacental passage of PSI. Corticosteroids may also have affected PG synthesis inhibition. More... »

PAGES

371-373

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00444137

DOI

http://dx.doi.org/10.1007/bf00444137

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029532104

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2495965


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