Allele-specific suppression of a cell cycle mutant of S. cerevisiae View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1982-11

AUTHORS

K. M. V. Richmond, D. H. Williamson

ABSTRACT

A cell cycle (cdc) mutant of Saccharomyces cerevisiae is described which fails to complement cdc27-1 described by Hartwell et al. 1973), and is designated cdc27-47. Whereas cdc27-1 behaves as a single Mendelian gene (Hartwell et al. 1973), cdc27-47 requires the presence of an additional unlinked gene for expression of temperature-sensitivity. This gene, designated sts47, is present in some, but not all, laboratory wild-type strains. Expression of cdc27-1 is not influenced by STS47. A model for suppression is proposed involving the modification of conformation within a structural or enzyme complex. More... »

PAGES

167-170

Journal

TITLE

Current Genetics

ISSUE

2

VOLUME

6

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00435218

DOI

http://dx.doi.org/10.1007/bf00435218

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1004432719

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24186485


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