Weigle reactivation and mutagenesis of bacteriophage λ in lexA(Def) mutants of E. coli K12 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1985-11

AUTHORS

Patrick Calsou, Martine Defais

ABSTRACT

The SOS response in UV-irradiated bacteria enhances the survival and mutagenesis of infecting damaged bacteriophage lambda. In a lexA(Def) strain, SOS bacterial genes are fully derepressed by an inactivating mutation in the LexA repressor gene. We tested several lexA(Def) derivative strains for their capacity to constitutively promote high survival and mutagenesis of irradiated lambda. We showed that UV irradiation of the lexA(Def) host bacteria is still necessary for optimal efficiency of both these SOS functions, which are dependent on the umuC gene product and an activated form of RecA protein. More... »

PAGES

329-333

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00425679

DOI

http://dx.doi.org/10.1007/bf00425679

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1047583031

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2935711


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