Cloning and characterization of the SKI3 gene of Saccharomyces cerevisiae demonstrates allelism to SKI5 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1989-09

AUTHORS

Linda Hougan, David Y. Thomas, Malcolm Whiteway

ABSTRACT

We have identified a mutant strain of the yeast Saccharomyces cerevisiae which overproduces killer toxin. This strain contains a single mutation which fails to complement defects in both the SKI3 and SKI5 genes, while a cloned copy of this gene complements both the ski3 and ski5 defects. The level of secreted toxin from a cDNA based plasmid is not increased in a ski3 strain, showing that the overproduction phenotype is dependent upon an increased level of M1 dsRNA. More... »

PAGES

139-143

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00391469

DOI

http://dx.doi.org/10.1007/bf00391469

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007615876

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2557163


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