A monoclonal antibody recognizing HLA-DR2 on malignant and activated cells View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1983-10

AUTHORS

Susan V. Fuggle, Jean Kirkley, Alan Ting, Peter J. Morris

ABSTRACT

A monoclonal antibody, designated NDS15.38, which recognizes a polymorphic determinant of HLA-DR, was produced from a fusion in which mice were immunized with the human B lymphoblastoid cell line GIR2 (HLA type A1, B8, 27, Cw2, DR2, 7). NDS15.38 functions efficiently as an affinity column and purifies a two-chain complex of molecular weight 33 000 and 30 000 under reducing conditions. The monoclonal antibody reacts with HLA-DR2-positive B lymphoblastoid cell lines and B lymphocytes from patients with chronic lymphatic leukemia in an indirect radioactive binding assay. However, NDS15.38 does not appear to react with peripheral blood B lymphocytes from normal individuals. Using a peroxidase staining technique, NDS15.38 was shown to react with phytohemagglutin (PHA)-stimulated lymphocytes and with apparently activated B cells in the germinal centers of lymph nodes from individuals who were tissue typed as HLA-DR2. Thus it appears that NDS15.38 recognizes a polymorphic determinant of HLA-DR on malignant and stimulated cells, but not on resting cells. More... »

PAGES

415-428

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00372473

DOI

http://dx.doi.org/10.1007/bf00372473

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042041189

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6195109


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antibodies, Monoclonal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antigen-Antibody Complex", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "B-Lymphocytes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Line", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Epitopes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes, MHC Class II", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HLA Antigens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HLA-DR Antigens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Histocompatibility Antigens Class II", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Immunoenzyme Techniques", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Leukemia, Lymphoid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Inbred BALB C", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Weight", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymorphism, Genetic", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, OX3 9DU, England", 
          "id": "http://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, OX3 9DU, England"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fuggle", 
        "givenName": "Susan V.", 
        "id": "sg:person.01162341204.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162341204.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, OX3 9DU, England", 
          "id": "http://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, OX3 9DU, England"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kirkley", 
        "givenName": "Jean", 
        "id": "sg:person.01224523173.63", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224523173.63"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, OX3 9DU, England", 
          "id": "http://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, OX3 9DU, England"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ting", 
        "givenName": "Alan", 
        "id": "sg:person.0725270057.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725270057.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, OX3 9DU, England", 
          "id": "http://www.grid.ac/institutes/grid.4991.5", 
          "name": [
            "Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, OX3 9DU, England"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Morris", 
        "givenName": "Peter J.", 
        "id": "sg:person.0756117606.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0756117606.48"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/256495a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001387921", 
          "https://doi.org/10.1038/256495a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/254267a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043534240", 
          "https://doi.org/10.1038/254267a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/227680a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010419937", 
          "https://doi.org/10.1038/227680a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/301531a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046191379", 
          "https://doi.org/10.1038/301531a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/292357a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037237924", 
          "https://doi.org/10.1038/292357a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1983-10", 
    "datePublishedReg": "1983-10-01", 
    "description": "A monoclonal antibody, designated NDS15.38, which recognizes a polymorphic determinant of HLA-DR, was produced from a fusion in which mice were immunized with the human B lymphoblastoid cell line GIR2 (HLA type A1, B8, 27, Cw2, DR2, 7). NDS15.38 functions efficiently as an affinity column and purifies a two-chain complex of molecular weight 33 000 and 30 000 under reducing conditions. The monoclonal antibody reacts with HLA-DR2-positive B lymphoblastoid cell lines and B lymphocytes from patients with chronic lymphatic leukemia in an indirect radioactive binding assay. However, NDS15.38 does not appear to react with peripheral blood B lymphocytes from normal individuals. Using a peroxidase staining technique, NDS15.38 was shown to react with phytohemagglutin (PHA)-stimulated lymphocytes and with apparently activated B cells in the germinal centers of lymph nodes from individuals who were tissue typed as HLA-DR2. Thus it appears that NDS15.38 recognizes a polymorphic determinant of HLA-DR on malignant and stimulated cells, but not on resting cells.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/bf00372473", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1019755", 
        "issn": [
          "0093-7711", 
          "1432-1211"
        ], 
        "name": "Immunogenetics", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "4", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "18"
      }
    ], 
    "keywords": [
      "HLA-DR", 
      "HLA-DR2", 
      "monoclonal antibodies", 
      "polymorphic determinants", 
      "peripheral blood B lymphocytes", 
      "chronic lymphatic leukemia", 
      "blood B lymphocytes", 
      "radioactive binding assays", 
      "lymph nodes", 
      "lymphatic leukemia", 
      "lymphoblastoid cell lines", 
      "germinal centers", 
      "normal individuals", 
      "lymphocytes", 
      "Activated cells", 
      "antibodies", 
      "cell lines", 
      "binding assays", 
      "molecular weight 33 000", 
      "cells", 
      "patients", 
      "HLA", 
      "leukemia", 
      "phytohemagglutin", 
      "mice", 
      "individuals", 
      "determinants", 
      "affinity column", 
      "tissue", 
      "assays", 
      "peroxidase", 
      "two-chain complexes", 
      "center", 
      "function", 
      "fusion", 
      "lines", 
      "nodes", 
      "conditions", 
      "technique", 
      "complexes", 
      "Gir2", 
      "column"
    ], 
    "name": "A monoclonal antibody recognizing HLA-DR2 on malignant and activated cells", 
    "pagination": "415-428", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1042041189"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf00372473"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "6195109"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf00372473", 
      "https://app.dimensions.ai/details/publication/pub.1042041189"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-05-10T09:42", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_178.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/bf00372473"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00372473'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00372473'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00372473'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00372473'


 

This table displays all metadata directly associated to this object as RDF triples.

213 TRIPLES      22 PREDICATES      91 URIs      78 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf00372473 schema:about N019e7c42618f49a58d46b18814156b26
2 N10ee60aaadee4372878337e8f7b5666d
3 N110051272bad4db4ba161720eabfdbed
4 N2214701681c5420cab0cd94a74df3ebb
5 N25fe59966acf4a47a5b34cb2b09e4024
6 N2c8e5e846b6e4108ac7b84b88c3f544a
7 N5fa0be4961cc4ebb8f92aa17c7065d03
8 N63ffdca6edee40b1897b5c203979f4b1
9 N78fab649663743dfb3b3e3974895e213
10 N8bf3a78be87c4692a59a836edb6470da
11 N95c02f6ce9204d01b2ee31c3bd9d176b
12 Nc292e6210a204405bddd7acac843c4dd
13 Nc5e2fe49794b42bf8ac125af0e70e24c
14 Ne335fb40558e44d392b1b5132b938985
15 Ne37d19218ff54f2b8fead03e7a632faa
16 Nf436ea5d4a9d40f38fd5584c68d7014f
17 Nffdeb3c403b64bce9dcedc434b562387
18 anzsrc-for:11
19 anzsrc-for:1107
20 schema:author N0b83fda309b14435b9d5ed451243ede9
21 schema:citation sg:pub.10.1038/227680a0
22 sg:pub.10.1038/254267a0
23 sg:pub.10.1038/256495a0
24 sg:pub.10.1038/292357a0
25 sg:pub.10.1038/301531a0
26 schema:datePublished 1983-10
27 schema:datePublishedReg 1983-10-01
28 schema:description A monoclonal antibody, designated NDS15.38, which recognizes a polymorphic determinant of HLA-DR, was produced from a fusion in which mice were immunized with the human B lymphoblastoid cell line GIR2 (HLA type A1, B8, 27, Cw2, DR2, 7). NDS15.38 functions efficiently as an affinity column and purifies a two-chain complex of molecular weight 33 000 and 30 000 under reducing conditions. The monoclonal antibody reacts with HLA-DR2-positive B lymphoblastoid cell lines and B lymphocytes from patients with chronic lymphatic leukemia in an indirect radioactive binding assay. However, NDS15.38 does not appear to react with peripheral blood B lymphocytes from normal individuals. Using a peroxidase staining technique, NDS15.38 was shown to react with phytohemagglutin (PHA)-stimulated lymphocytes and with apparently activated B cells in the germinal centers of lymph nodes from individuals who were tissue typed as HLA-DR2. Thus it appears that NDS15.38 recognizes a polymorphic determinant of HLA-DR on malignant and stimulated cells, but not on resting cells.
29 schema:genre article
30 schema:inLanguage en
31 schema:isAccessibleForFree false
32 schema:isPartOf N4af924ebff5b4249853c47361d9b2379
33 Naab6e38bedda4346bd5865c2e8b77d01
34 sg:journal.1019755
35 schema:keywords Activated cells
36 Gir2
37 HLA
38 HLA-DR
39 HLA-DR2
40 affinity column
41 antibodies
42 assays
43 binding assays
44 blood B lymphocytes
45 cell lines
46 cells
47 center
48 chronic lymphatic leukemia
49 column
50 complexes
51 conditions
52 determinants
53 function
54 fusion
55 germinal centers
56 individuals
57 leukemia
58 lines
59 lymph nodes
60 lymphatic leukemia
61 lymphoblastoid cell lines
62 lymphocytes
63 mice
64 molecular weight 33 000
65 monoclonal antibodies
66 nodes
67 normal individuals
68 patients
69 peripheral blood B lymphocytes
70 peroxidase
71 phytohemagglutin
72 polymorphic determinants
73 radioactive binding assays
74 technique
75 tissue
76 two-chain complexes
77 schema:name A monoclonal antibody recognizing HLA-DR2 on malignant and activated cells
78 schema:pagination 415-428
79 schema:productId N6901052c80044d75a0ac94ad34f8a81c
80 N8644e10c090a421583efc6cf6bebbb5b
81 Nd8dfd7a3e2bb48cc8af99508395e4527
82 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042041189
83 https://doi.org/10.1007/bf00372473
84 schema:sdDatePublished 2022-05-10T09:42
85 schema:sdLicense https://scigraph.springernature.com/explorer/license/
86 schema:sdPublisher Nc4afe336a13747d4a4f47cc584329b18
87 schema:url https://doi.org/10.1007/bf00372473
88 sgo:license sg:explorer/license/
89 sgo:sdDataset articles
90 rdf:type schema:ScholarlyArticle
91 N019e7c42618f49a58d46b18814156b26 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Mice
93 rdf:type schema:DefinedTerm
94 N0b83fda309b14435b9d5ed451243ede9 rdf:first sg:person.01162341204.51
95 rdf:rest Nb0271a5050b244c4928a85d52b7a3557
96 N10ee60aaadee4372878337e8f7b5666d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Antibodies, Monoclonal
98 rdf:type schema:DefinedTerm
99 N110051272bad4db4ba161720eabfdbed schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Genes, MHC Class II
101 rdf:type schema:DefinedTerm
102 N2214701681c5420cab0cd94a74df3ebb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Antigen-Antibody Complex
104 rdf:type schema:DefinedTerm
105 N25fe59966acf4a47a5b34cb2b09e4024 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name HLA-DR Antigens
107 rdf:type schema:DefinedTerm
108 N2c8e5e846b6e4108ac7b84b88c3f544a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Mice, Inbred BALB C
110 rdf:type schema:DefinedTerm
111 N4af924ebff5b4249853c47361d9b2379 schema:volumeNumber 18
112 rdf:type schema:PublicationVolume
113 N5c642f02ba374c359a1529f1635bc593 rdf:first sg:person.0756117606.48
114 rdf:rest rdf:nil
115 N5fa0be4961cc4ebb8f92aa17c7065d03 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Animals
117 rdf:type schema:DefinedTerm
118 N63ffdca6edee40b1897b5c203979f4b1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Histocompatibility Antigens Class II
120 rdf:type schema:DefinedTerm
121 N6901052c80044d75a0ac94ad34f8a81c schema:name pubmed_id
122 schema:value 6195109
123 rdf:type schema:PropertyValue
124 N78fab649663743dfb3b3e3974895e213 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Leukemia, Lymphoid
126 rdf:type schema:DefinedTerm
127 N8644e10c090a421583efc6cf6bebbb5b schema:name doi
128 schema:value 10.1007/bf00372473
129 rdf:type schema:PropertyValue
130 N8bf3a78be87c4692a59a836edb6470da schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
131 schema:name Molecular Weight
132 rdf:type schema:DefinedTerm
133 N95c02f6ce9204d01b2ee31c3bd9d176b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Polymorphism, Genetic
135 rdf:type schema:DefinedTerm
136 Naab6e38bedda4346bd5865c2e8b77d01 schema:issueNumber 4
137 rdf:type schema:PublicationIssue
138 Nb0271a5050b244c4928a85d52b7a3557 rdf:first sg:person.01224523173.63
139 rdf:rest Nea162ea500f849bf8213273aa0b2296a
140 Nc292e6210a204405bddd7acac843c4dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Epitopes
142 rdf:type schema:DefinedTerm
143 Nc4afe336a13747d4a4f47cc584329b18 schema:name Springer Nature - SN SciGraph project
144 rdf:type schema:Organization
145 Nc5e2fe49794b42bf8ac125af0e70e24c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
146 schema:name B-Lymphocytes
147 rdf:type schema:DefinedTerm
148 Nd8dfd7a3e2bb48cc8af99508395e4527 schema:name dimensions_id
149 schema:value pub.1042041189
150 rdf:type schema:PropertyValue
151 Ne335fb40558e44d392b1b5132b938985 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name HLA Antigens
153 rdf:type schema:DefinedTerm
154 Ne37d19218ff54f2b8fead03e7a632faa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Cell Line
156 rdf:type schema:DefinedTerm
157 Nea162ea500f849bf8213273aa0b2296a rdf:first sg:person.0725270057.10
158 rdf:rest N5c642f02ba374c359a1529f1635bc593
159 Nf436ea5d4a9d40f38fd5584c68d7014f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
160 schema:name Immunoenzyme Techniques
161 rdf:type schema:DefinedTerm
162 Nffdeb3c403b64bce9dcedc434b562387 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
163 schema:name Humans
164 rdf:type schema:DefinedTerm
165 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
166 schema:name Medical and Health Sciences
167 rdf:type schema:DefinedTerm
168 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
169 schema:name Immunology
170 rdf:type schema:DefinedTerm
171 sg:journal.1019755 schema:issn 0093-7711
172 1432-1211
173 schema:name Immunogenetics
174 schema:publisher Springer Nature
175 rdf:type schema:Periodical
176 sg:person.01162341204.51 schema:affiliation grid-institutes:grid.4991.5
177 schema:familyName Fuggle
178 schema:givenName Susan V.
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162341204.51
180 rdf:type schema:Person
181 sg:person.01224523173.63 schema:affiliation grid-institutes:grid.4991.5
182 schema:familyName Kirkley
183 schema:givenName Jean
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224523173.63
185 rdf:type schema:Person
186 sg:person.0725270057.10 schema:affiliation grid-institutes:grid.4991.5
187 schema:familyName Ting
188 schema:givenName Alan
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725270057.10
190 rdf:type schema:Person
191 sg:person.0756117606.48 schema:affiliation grid-institutes:grid.4991.5
192 schema:familyName Morris
193 schema:givenName Peter J.
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0756117606.48
195 rdf:type schema:Person
196 sg:pub.10.1038/227680a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010419937
197 https://doi.org/10.1038/227680a0
198 rdf:type schema:CreativeWork
199 sg:pub.10.1038/254267a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043534240
200 https://doi.org/10.1038/254267a0
201 rdf:type schema:CreativeWork
202 sg:pub.10.1038/256495a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001387921
203 https://doi.org/10.1038/256495a0
204 rdf:type schema:CreativeWork
205 sg:pub.10.1038/292357a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037237924
206 https://doi.org/10.1038/292357a0
207 rdf:type schema:CreativeWork
208 sg:pub.10.1038/301531a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046191379
209 https://doi.org/10.1038/301531a0
210 rdf:type schema:CreativeWork
211 grid-institutes:grid.4991.5 schema:alternateName Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, OX3 9DU, England
212 schema:name Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, OX3 9DU, England
213 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...