Euploid segregation through multipolar mitosis in mammalian cell cultures View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1974-06

AUTHORS

Marco Rizzoni, Fabrizio Palitti, Paolo Perticone

ABSTRACT

Cultures were made of kidney cells of male Rhesus monkey and a karyological analysis of these cells was carried out at various times after plating using the chromosome banding method of Seabringht (1972), in order to study the segregation phenomena which take place in cell cultures in vitro through multipolar mitoses and to identify segregating cells. — Several segregating cells were found: haploid cells, diploid cells with two X chromosomes and triploid cells which were strictly euploid. Polyploidization-segregation cycles in the cell cultures and their mechanism and chronological sequence were analyzed. — On the basis of these results it was suggested that the genome is organized in haploid sets capable of segregating as units and of producing strictly euploid segregating daughter cells. More... »

PAGES

151-162

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00362308

DOI

http://dx.doi.org/10.1007/bf00362308

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1051937584

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4135138


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