Generation and characterization of an ordered lambda clone array for the 460-kb region surrounding the murine Xist sequence View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1994-07

AUTHORS

C. Rougeulle, L. Colleaux, B. Dujon, P. Avner

ABSTRACT

The Xist sequence has several characteristics that make it a potential candidate for the X-inactivation center. To investigate the role of Xist and adjacent sequences lying within the X-inactivation center candidate region, a 460-kb region surrounding the murine Xist sequence has been arrayed in lambda contigs with a combination of IRS-PCR-based hybridization and YAC fragmentation. The orientation of the Xist sequence in relation to the telomere and centromere of the X Chromosome (Chr) has been established with this contig and shown to be inverted compared to that in human. More... »

PAGES

416-423

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00357001

DOI

http://dx.doi.org/10.1007/bf00357001

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1049426886

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/7726900


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