Mononucleotide repeats are an abundant source of length variants in mouse genomic DNA View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1991-12

AUTHORS

Timothy J. Aitman, Catherine M. Hearne, Marcia A. McAleer, John A. Todd

ABSTRACT

Microsatellite sequences, such as dinucleotide repeats, show a high degree of polymorphism in eukaryotic DNA. These sequences are convenient as genetic markers and can be analyzed by the polymerase chain reaction (PCR). We have assessed the frequency of length variants in 18 mononucleotide repeats in mouse DNA and find that the variability is similar to that reported for dinucleotide repeats. Nine of the 18 repeat sequences (50%) have three or more alleles in the strains tested. Ten of these repeat sequences have been mapped using strain distribution patterns (SDPs) in recombinant inbred (RI) strains. More... »

PAGES

206-210

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00352326

DOI

http://dx.doi.org/10.1007/bf00352326

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1022382728

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1794049


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