Pure red cell aplasia after major ABO-incompatible bone marrow transplantation: two case reports of treatment with recombinant human erythropoietin View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1996-09

AUTHORS

Shin Fujisawa, Atsuo Maruta, Rika Sakai, Jun Taguchi, Naoto Tomita, Koji Ogawa, Fumio Kodama, Kyoko Takahashi, Shigeru Shibayama, Syoichi Kobayashi, Koichiro Ikuta, Takao Okubo

ABSTRACT

A 34-year-old man with acute myelocytic leukemia (AML: MO) and a 32-year-old woman with AML: M2 developed pure red cell aplasia (PRCA) after receiving a major ABO-incompatible bone marrow transplant (BMT). The first patient responded to recombinant human erythropoietin (rhEPO) therapy, while the second did not. The second patient also received methylprednisolone (m-PSL) but developed reticulocytosis and hemolysis after the administration of m-PSL. Plasmapheresis was then performed and the patient promptly recovered from hemolysis and PRCA. We conclude that close attention must be paid when treating PRCA following major ABO-in-compatible BMT with rhEPO and m-PSL, as there is always the potential for massive hemolysis. More... »

PAGES

506-508

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00336830

DOI

http://dx.doi.org/10.1007/bf00336830

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039346083


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