A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1984-11

AUTHORS

Jef D. Boeke, Francois La Croute, Gerald R. Fink

ABSTRACT

Mutations at the URA3 locus of Saccharomyces cerevisiae can be obtained by a positive selection. Wild-type strains of yeast (or ura3 mutant strains containing a plasmid-borne URA3+ gene) are unable to grow on medium containing the pyrimidine analog 5-fluoro-orotic acid, whereas ura3- mutants grow normally. This selection, based on the loss of orotidine-5'-phosphate decarboxylase activity seems applicable to a variety of eucaryotic and procaryotic cells. More... »

PAGES

345-346

Journal

TITLE

Molecular Genetics and Genomics

ISSUE

2

VOLUME

197

Related Patents

  • Methods For Producing Modified Glycoproteins
  • Combinatorial Dna Library For Producing Modified N-Glycans In Lower Eukaryotes
  • Non-Natural Amino Acid Replication-Dependent Microorganisms And Vaccines
  • Selection Marker Gene Free Recombinant Strains: Method For Obtaining Them And The Use Of These Strains
  • Transformed Fungal Strains Free Of Selection Marker
  • Reverse Two-Hybrid Systems
  • Reverse Two-Hybrid System
  • Production Of Insulin-Like Growth Factor-1 In Methylotrophic Yeast Cells
  • Manufacture Of Five-Carbon Sugars And Sugar Alcohols
  • Recombinant Host Cells Comprising Phosphoketolases
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Method Of Prodcucing Proteins Comprising Unnatural Amino Acid
  • Protein Expression Systems
  • Ura5 Gene And Methods For Stable Genetic Integration In Yeast
  • Pyrococcus Furiosus Strains And Methods Of Using Same
  • Human Cyclin E
  • Unnatural Reactive Amino Acid Genetic Code Additions
  • Aminoacyl-Trna Synthetase For Aminoacylation Trna With Unnatural Amino Acids
  • Regulatory Region Of The Cyp52a2a Gene From Candida Tropicalis
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Method For The Identification And Characterization Of Interacting Molecules By Automated Interaction Mating
  • Non-Revertible Β-Oxidation Blocked Candida Tropicalis
  • Production Of Modified Glycoproteins Having Multiple Antennary Structures
  • Manufacture Of Xylitol Using Recombinant Microbial Hosts
  • Cytochrome P450 Monooxygenase And Nadph Cytochrome P450 Oxidoreductase Genes And Proteins Related To The Omega Hydroxylase Complex Of Candida Tropicalis And Methods Relating Thereto
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Selection Marker Gene Free Recombinant Strains
  • Methods For Screening For Antimycotics
  • Unnatural Reactive Amino Acid Genetic Code Additions
  • Production Of Recombinant Proteins Utilizing Non-Antibiotic Selection Methods And The Incorporation Of Non-Natural Amino Acids Therein
  • Genetic Assays For Trinucleotide Repeat Mutations In Eukaryotic Cells
  • Methods For Producing Modified Glycoproteins
  • N-Acetylglucosaminyltransferase Iii Expression In Lower Eukaryotes
  • Methods For Producing Modified Glycoproteins
  • Reverse Two-Hybrid Systems
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Reverse Two-Hybrid Systems
  • Cytochrome P450 Monooxygenase Cyp52a2b From Candida Tropicalis
  • Recombinant Host Cells Comprising Phosphoketalase
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Endomannosidases In The Modification Of Glycoproteins In Eukaryotes
  • Combinatorial Dna Library For Producing Modified N-Glycans In Lower Eukaryotes
  • Methods For Screening For Antimycotics
  • Cytochrome P450 Monooxygenase Cyp52a2a From Candida Tropicalis
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Recombinant Host Cells Comprising Phosphoketolases
  • Combinatorial Dna Library For Producing Modified N-Glycans In Lower Eukaryotes
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Yeast Membrane Protein Expression System And Its Application In Drug Screening
  • Yeast Membrane Protein Expression System And Its Application In Drug Screening
  • Combinatorial Dna Library For Producing Modified N-Glycans In Lower Eukaryotes
  • Site-Specific Modification Of The Candida Tropicals Genome
  • Method Of Selection For Genes Encoding Secreted And Transmembrane Proteins
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf00330984

    DOI

    http://dx.doi.org/10.1007/bf00330984

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1017841696

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/6394957


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Genetics", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Carboxy-Lyases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Drug Resistance, Microbial", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Fungal Proteins", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Microbiological Techniques", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Orotic Acid", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Orotidine-5'-Phosphate Decarboxylase", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Saccharomyces cerevisiae", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Massachusetts Institute of Technology", 
              "id": "https://www.grid.ac/institutes/grid.116068.8", 
              "name": [
                "Massachusetts Institute of Technology and Whitehead Institute for Biomedical Research, 02142, Cambridge, Massachusetts, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Boeke", 
            "givenName": "Jef D.", 
            "id": "sg:person.01022533774.72", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022533774.72"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Laboratoire de Genetique Physiologique, Strasbourg, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "La Croute", 
            "givenName": "Francois", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Massachusetts Institute of Technology", 
              "id": "https://www.grid.ac/institutes/grid.116068.8", 
              "name": [
                "Massachusetts Institute of Technology and Whitehead Institute for Biomedical Research, 02142, Cambridge, Massachusetts, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fink", 
            "givenName": "Gerald R.", 
            "id": "sg:person.015646367602.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015646367602.05"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/0378-1119(84)90172-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000917632"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0378-1119(84)90172-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000917632"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00277292", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001584443", 
              "https://doi.org/10.1007/bf00277292"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00277292", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001584443", 
              "https://doi.org/10.1007/bf00277292"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0076-6879(83)01017-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008079849"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.76.1.386", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010513873"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0076-6879(83)01016-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030230624"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00382100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031295850", 
              "https://doi.org/10.1007/bf00382100"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00382100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031295850", 
              "https://doi.org/10.1007/bf00382100"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0378-1119(79)90004-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039235741"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0378-1119(79)90004-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039235741"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074725931", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077359010", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1080298936", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1080434314", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1081682266", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1984-11", 
        "datePublishedReg": "1984-11-01", 
        "description": "Mutations at the URA3 locus of Saccharomyces cerevisiae can be obtained by a positive selection. Wild-type strains of yeast (or ura3 mutant strains containing a plasmid-borne URA3+ gene) are unable to grow on medium containing the pyrimidine analog 5-fluoro-orotic acid, whereas ura3- mutants grow normally. This selection, based on the loss of orotidine-5'-phosphate decarboxylase activity seems applicable to a variety of eucaryotic and procaryotic cells.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/bf00330984", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1297380", 
            "issn": [
              "1617-4615", 
              "1432-1874"
            ], 
            "name": "Molecular Genetics and Genomics", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "2", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "197"
          }
        ], 
        "name": "A positive selection for mutants lacking orotidine-5\u2032-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance", 
        "pagination": "345-346", 
        "productId": [
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/bf00330984"
            ]
          }, 
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "55027cc18d4e9284cdba93b27e0ee6087fbd52b27bf9ced3de01aac4cf5ea9d3"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1017841696"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "0125036"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "6394957"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/bf00330984", 
          "https://app.dimensions.ai/details/publication/pub.1017841696"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-15T08:54", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000374_0000000374/records_119752_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1007/BF00330984"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00330984'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00330984'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00330984'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00330984'


     

    This table displays all metadata directly associated to this object as RDF triples.

    145 TRIPLES      21 PREDICATES      48 URIs      28 LITERALS      16 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/bf00330984 schema:about N01d994c7351649a6a865a10b5c6c5a65
    2 N4216799d8f8c4245b4f523f546cf18fe
    3 N9b6d9c83869a4047adb885feb5609f5b
    4 Nca23ff2500d441ff80bfef5d0f116936
    5 Nd14c384018ce4efbbe91e24a86924d16
    6 Ne3c5c361e11a41848ed667a9796df2d3
    7 Nec16b2794fb541639e7889778c7fa968
    8 anzsrc-for:06
    9 anzsrc-for:0604
    10 schema:author N909594cd543c475a8dc5e2a17819b389
    11 schema:citation sg:pub.10.1007/bf00277292
    12 sg:pub.10.1007/bf00382100
    13 https://app.dimensions.ai/details/publication/pub.1074725931
    14 https://app.dimensions.ai/details/publication/pub.1077359010
    15 https://app.dimensions.ai/details/publication/pub.1080298936
    16 https://app.dimensions.ai/details/publication/pub.1080434314
    17 https://app.dimensions.ai/details/publication/pub.1081682266
    18 https://doi.org/10.1016/0076-6879(83)01016-2
    19 https://doi.org/10.1016/0076-6879(83)01017-4
    20 https://doi.org/10.1016/0378-1119(79)90004-0
    21 https://doi.org/10.1016/0378-1119(84)90172-0
    22 https://doi.org/10.1073/pnas.76.1.386
    23 schema:datePublished 1984-11
    24 schema:datePublishedReg 1984-11-01
    25 schema:description Mutations at the URA3 locus of Saccharomyces cerevisiae can be obtained by a positive selection. Wild-type strains of yeast (or ura3 mutant strains containing a plasmid-borne URA3+ gene) are unable to grow on medium containing the pyrimidine analog 5-fluoro-orotic acid, whereas ura3- mutants grow normally. This selection, based on the loss of orotidine-5'-phosphate decarboxylase activity seems applicable to a variety of eucaryotic and procaryotic cells.
    26 schema:genre research_article
    27 schema:inLanguage en
    28 schema:isAccessibleForFree false
    29 schema:isPartOf N0a63d151961947239334d4478077e8d6
    30 N5e089310bcad4020926b042842460473
    31 sg:journal.1297380
    32 schema:name A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance
    33 schema:pagination 345-346
    34 schema:productId N0c5b49a225b54f368485631cf5c938db
    35 N17e6a51257c24813b91e38d3298cfbb0
    36 N1c403e52c4b84c1bb90466259e82a0b7
    37 N5bae2cfb2af14a868b6bf45b7b556a96
    38 Ne8eafdd8e2c64fbd9420f435603ffa76
    39 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017841696
    40 https://doi.org/10.1007/bf00330984
    41 schema:sdDatePublished 2019-04-15T08:54
    42 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    43 schema:sdPublisher Nd698e2becbad43daa96982824cd9f199
    44 schema:url http://link.springer.com/10.1007/BF00330984
    45 sgo:license sg:explorer/license/
    46 sgo:sdDataset articles
    47 rdf:type schema:ScholarlyArticle
    48 N01d994c7351649a6a865a10b5c6c5a65 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    49 schema:name Orotic Acid
    50 rdf:type schema:DefinedTerm
    51 N0a63d151961947239334d4478077e8d6 schema:issueNumber 2
    52 rdf:type schema:PublicationIssue
    53 N0c5b49a225b54f368485631cf5c938db schema:name doi
    54 schema:value 10.1007/bf00330984
    55 rdf:type schema:PropertyValue
    56 N17e6a51257c24813b91e38d3298cfbb0 schema:name nlm_unique_id
    57 schema:value 0125036
    58 rdf:type schema:PropertyValue
    59 N1c403e52c4b84c1bb90466259e82a0b7 schema:name readcube_id
    60 schema:value 55027cc18d4e9284cdba93b27e0ee6087fbd52b27bf9ced3de01aac4cf5ea9d3
    61 rdf:type schema:PropertyValue
    62 N4216799d8f8c4245b4f523f546cf18fe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    63 schema:name Orotidine-5'-Phosphate Decarboxylase
    64 rdf:type schema:DefinedTerm
    65 N5bae2cfb2af14a868b6bf45b7b556a96 schema:name pubmed_id
    66 schema:value 6394957
    67 rdf:type schema:PropertyValue
    68 N5e089310bcad4020926b042842460473 schema:volumeNumber 197
    69 rdf:type schema:PublicationVolume
    70 N714e4172f33846dbaf1635e4d9a3b63d schema:affiliation N762b9a4e2795437385ed34e266849340
    71 schema:familyName La Croute
    72 schema:givenName Francois
    73 rdf:type schema:Person
    74 N762b9a4e2795437385ed34e266849340 schema:name Laboratoire de Genetique Physiologique, Strasbourg, France
    75 rdf:type schema:Organization
    76 N85751460945f4ccebe282d5453686a3c rdf:first N714e4172f33846dbaf1635e4d9a3b63d
    77 rdf:rest Na5eb1e25f95a4a59bea1b46d16a11efe
    78 N909594cd543c475a8dc5e2a17819b389 rdf:first sg:person.01022533774.72
    79 rdf:rest N85751460945f4ccebe282d5453686a3c
    80 N9b6d9c83869a4047adb885feb5609f5b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    81 schema:name Microbiological Techniques
    82 rdf:type schema:DefinedTerm
    83 Na5eb1e25f95a4a59bea1b46d16a11efe rdf:first sg:person.015646367602.05
    84 rdf:rest rdf:nil
    85 Nca23ff2500d441ff80bfef5d0f116936 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    86 schema:name Drug Resistance, Microbial
    87 rdf:type schema:DefinedTerm
    88 Nd14c384018ce4efbbe91e24a86924d16 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    89 schema:name Fungal Proteins
    90 rdf:type schema:DefinedTerm
    91 Nd698e2becbad43daa96982824cd9f199 schema:name Springer Nature - SN SciGraph project
    92 rdf:type schema:Organization
    93 Ne3c5c361e11a41848ed667a9796df2d3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    94 schema:name Saccharomyces cerevisiae
    95 rdf:type schema:DefinedTerm
    96 Ne8eafdd8e2c64fbd9420f435603ffa76 schema:name dimensions_id
    97 schema:value pub.1017841696
    98 rdf:type schema:PropertyValue
    99 Nec16b2794fb541639e7889778c7fa968 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    100 schema:name Carboxy-Lyases
    101 rdf:type schema:DefinedTerm
    102 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    103 schema:name Biological Sciences
    104 rdf:type schema:DefinedTerm
    105 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
    106 schema:name Genetics
    107 rdf:type schema:DefinedTerm
    108 sg:journal.1297380 schema:issn 1432-1874
    109 1617-4615
    110 schema:name Molecular Genetics and Genomics
    111 rdf:type schema:Periodical
    112 sg:person.01022533774.72 schema:affiliation https://www.grid.ac/institutes/grid.116068.8
    113 schema:familyName Boeke
    114 schema:givenName Jef D.
    115 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022533774.72
    116 rdf:type schema:Person
    117 sg:person.015646367602.05 schema:affiliation https://www.grid.ac/institutes/grid.116068.8
    118 schema:familyName Fink
    119 schema:givenName Gerald R.
    120 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015646367602.05
    121 rdf:type schema:Person
    122 sg:pub.10.1007/bf00277292 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001584443
    123 https://doi.org/10.1007/bf00277292
    124 rdf:type schema:CreativeWork
    125 sg:pub.10.1007/bf00382100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031295850
    126 https://doi.org/10.1007/bf00382100
    127 rdf:type schema:CreativeWork
    128 https://app.dimensions.ai/details/publication/pub.1074725931 schema:CreativeWork
    129 https://app.dimensions.ai/details/publication/pub.1077359010 schema:CreativeWork
    130 https://app.dimensions.ai/details/publication/pub.1080298936 schema:CreativeWork
    131 https://app.dimensions.ai/details/publication/pub.1080434314 schema:CreativeWork
    132 https://app.dimensions.ai/details/publication/pub.1081682266 schema:CreativeWork
    133 https://doi.org/10.1016/0076-6879(83)01016-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030230624
    134 rdf:type schema:CreativeWork
    135 https://doi.org/10.1016/0076-6879(83)01017-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008079849
    136 rdf:type schema:CreativeWork
    137 https://doi.org/10.1016/0378-1119(79)90004-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039235741
    138 rdf:type schema:CreativeWork
    139 https://doi.org/10.1016/0378-1119(84)90172-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000917632
    140 rdf:type schema:CreativeWork
    141 https://doi.org/10.1073/pnas.76.1.386 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010513873
    142 rdf:type schema:CreativeWork
    143 https://www.grid.ac/institutes/grid.116068.8 schema:alternateName Massachusetts Institute of Technology
    144 schema:name Massachusetts Institute of Technology and Whitehead Institute for Biomedical Research, 02142, Cambridge, Massachusetts, USA
    145 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...