A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1984-11

AUTHORS

Jef D. Boeke, Francois La Croute, Gerald R. Fink

ABSTRACT

Mutations at the URA3 locus of Saccharomyces cerevisiae can be obtained by a positive selection. Wild-type strains of yeast (or ura3 mutant strains containing a plasmid-borne URA3+ gene) are unable to grow on medium containing the pyrimidine analog 5-fluoro-orotic acid, whereas ura3- mutants grow normally. This selection, based on the loss of orotidine-5'-phosphate decarboxylase activity seems applicable to a variety of eucaryotic and procaryotic cells. More... »

PAGES

345-346

References to SciGraph publications

Journal

TITLE

Molecular Genetics and Genomics

ISSUE

2

VOLUME

197

Related Patents

  • Combinatorial Dna Library For Producing Modified N-Glycans In Lower Eukaryotes
  • Methods For Producing Modified Glycoproteins
  • Manufacture Of Five-Carbon Sugars And Sugar Alcohols
  • Transformed Fungal Strains Free Of Selection Marker
  • Reverse Two-Hybrid System
  • Reverse Two-Hybrid Systems
  • Production Of Insulin-Like Growth Factor-1 In Methylotrophic Yeast Cells
  • Selection Marker Gene Free Recombinant Strains: Method For Obtaining Them And The Use Of These Strains
  • Non-Natural Amino Acid Replication-Dependent Microorganisms And Vaccines
  • Recombinant Host Cells Comprising Phosphoketolases
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Ura5 Gene And Methods For Stable Genetic Integration In Yeast
  • Method Of Prodcucing Proteins Comprising Unnatural Amino Acid
  • Protein Expression Systems
  • Pyrococcus Furiosus Strains And Methods Of Using Same
  • Aminoacyl-Trna Synthetase For Aminoacylation Trna With Unnatural Amino Acids
  • Regulatory Region Of The Cyp52a2a Gene From Candida Tropicalis
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Method For The Identification And Characterization Of Interacting Molecules By Automated Interaction Mating
  • Human Cyclin E
  • Unnatural Reactive Amino Acid Genetic Code Additions
  • Production Of Recombinant Proteins Utilizing Non-Antibiotic Selection Methods And The Incorporation Of Non-Natural Amino Acids Therein
  • Unnatural Reactive Amino Acid Genetic Code Additions
  • Methods For Producing Modified Glycoproteins
  • N-Acetylglucosaminyltransferase Iii Expression In Lower Eukaryotes
  • Cytochrome P450 Monooxygenase And Nadph Cytochrome P450 Oxidoreductase Genes And Proteins Related To The Omega Hydroxylase Complex Of Candida Tropicalis And Methods Relating Thereto
  • Manufacture Of Xylitol Using Recombinant Microbial Hosts
  • Production Of Modified Glycoproteins Having Multiple Antennary Structures
  • Selection Marker Gene Free Recombinant Strains
  • Genetic Assays For Trinucleotide Repeat Mutations In Eukaryotic Cells
  • Methods For Screening For Antimycotics
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Non-Revertible Β-Oxidation Blocked Candida Tropicalis
  • Methods For Producing Modified Glycoproteins
  • Reverse Two-Hybrid Systems
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Reverse Two-Hybrid Systems
  • Cytochrome P450 Monooxygenase Cyp52a2b From Candida Tropicalis
  • Recombinant Host Cells Comprising Phosphoketalase
  • Combinatorial Dna Library For Producing Modified N-Glycans In Lower Eukaryotes
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Endomannosidases In The Modification Of Glycoproteins In Eukaryotes
  • Methods For Screening For Antimycotics
  • Cytochrome P450 Monooxygenase Cyp52a2a From Candida Tropicalis
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Recombinant Host Cells Comprising Phosphoketolases
  • Combinatorial Dna Library For Producing Modified N-Glycans In Lower Eukaryotes
  • Multi-Chain Eukaryotic Display Vectors And Uses Thereof
  • Yeast Membrane Protein Expression System And Its Application In Drug Screening
  • Site-Specific Modification Of The Candida Tropicals Genome
  • Yeast Membrane Protein Expression System And Its Application In Drug Screening
  • Combinatorial Dna Library For Producing Modified N-Glycans In Lower Eukaryotes
  • Method Of Selection For Genes Encoding Secreted And Transmembrane Proteins
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf00330984

    DOI

    http://dx.doi.org/10.1007/bf00330984

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1017841696

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/6394957


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Genetics", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Carboxy-Lyases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Drug Resistance, Microbial", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Fungal Proteins", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Microbiological Techniques", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Orotic Acid", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Orotidine-5'-Phosphate Decarboxylase", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Saccharomyces cerevisiae", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Massachusetts Institute of Technology", 
              "id": "https://www.grid.ac/institutes/grid.116068.8", 
              "name": [
                "Massachusetts Institute of Technology and Whitehead Institute for Biomedical Research, 02142, Cambridge, Massachusetts, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Boeke", 
            "givenName": "Jef D.", 
            "id": "sg:person.01022533774.72", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022533774.72"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Laboratoire de Genetique Physiologique, Strasbourg, France"
              ], 
              "type": "Organization"
            }, 
            "familyName": "La Croute", 
            "givenName": "Francois", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Massachusetts Institute of Technology", 
              "id": "https://www.grid.ac/institutes/grid.116068.8", 
              "name": [
                "Massachusetts Institute of Technology and Whitehead Institute for Biomedical Research, 02142, Cambridge, Massachusetts, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fink", 
            "givenName": "Gerald R.", 
            "id": "sg:person.015646367602.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015646367602.05"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/0378-1119(84)90172-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000917632"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0378-1119(84)90172-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000917632"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00277292", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001584443", 
              "https://doi.org/10.1007/bf00277292"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00277292", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001584443", 
              "https://doi.org/10.1007/bf00277292"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0076-6879(83)01017-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008079849"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.76.1.386", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010513873"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0076-6879(83)01016-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030230624"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00382100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031295850", 
              "https://doi.org/10.1007/bf00382100"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00382100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031295850", 
              "https://doi.org/10.1007/bf00382100"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0378-1119(79)90004-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039235741"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0378-1119(79)90004-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039235741"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074725931", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1077359010", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1080298936", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1080434314", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1081682266", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1984-11", 
        "datePublishedReg": "1984-11-01", 
        "description": "Mutations at the URA3 locus of Saccharomyces cerevisiae can be obtained by a positive selection. Wild-type strains of yeast (or ura3 mutant strains containing a plasmid-borne URA3+ gene) are unable to grow on medium containing the pyrimidine analog 5-fluoro-orotic acid, whereas ura3- mutants grow normally. This selection, based on the loss of orotidine-5'-phosphate decarboxylase activity seems applicable to a variety of eucaryotic and procaryotic cells.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/bf00330984", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1297380", 
            "issn": [
              "1617-4615", 
              "1432-1874"
            ], 
            "name": "Molecular Genetics and Genomics", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "2", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "197"
          }
        ], 
        "name": "A positive selection for mutants lacking orotidine-5\u2032-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance", 
        "pagination": "345-346", 
        "productId": [
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/bf00330984"
            ]
          }, 
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "55027cc18d4e9284cdba93b27e0ee6087fbd52b27bf9ced3de01aac4cf5ea9d3"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1017841696"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "0125036"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "6394957"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/bf00330984", 
          "https://app.dimensions.ai/details/publication/pub.1017841696"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-15T08:54", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000374_0000000374/records_119752_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1007/BF00330984"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00330984'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00330984'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00330984'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00330984'


     

    This table displays all metadata directly associated to this object as RDF triples.

    145 TRIPLES      21 PREDICATES      48 URIs      28 LITERALS      16 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/bf00330984 schema:about N6fa62ff90cf54bcda2e7843027b95adb
    2 N87d48474a31146e4be66e827b2c1770e
    3 N88dac35a8ab5454591dff8496e36333b
    4 Nb5960919adc747c3a6ea040e6af12306
    5 Nd1e1baca550a4f97a29f4f06ac0e6c31
    6 Nec6a791c85574e408cbafd2ba9863237
    7 Nef8a023f0c3742a7b5ebe920d8663038
    8 anzsrc-for:06
    9 anzsrc-for:0604
    10 schema:author N066c8f94556440b598b539b1906e054d
    11 schema:citation sg:pub.10.1007/bf00277292
    12 sg:pub.10.1007/bf00382100
    13 https://app.dimensions.ai/details/publication/pub.1074725931
    14 https://app.dimensions.ai/details/publication/pub.1077359010
    15 https://app.dimensions.ai/details/publication/pub.1080298936
    16 https://app.dimensions.ai/details/publication/pub.1080434314
    17 https://app.dimensions.ai/details/publication/pub.1081682266
    18 https://doi.org/10.1016/0076-6879(83)01016-2
    19 https://doi.org/10.1016/0076-6879(83)01017-4
    20 https://doi.org/10.1016/0378-1119(79)90004-0
    21 https://doi.org/10.1016/0378-1119(84)90172-0
    22 https://doi.org/10.1073/pnas.76.1.386
    23 schema:datePublished 1984-11
    24 schema:datePublishedReg 1984-11-01
    25 schema:description Mutations at the URA3 locus of Saccharomyces cerevisiae can be obtained by a positive selection. Wild-type strains of yeast (or ura3 mutant strains containing a plasmid-borne URA3+ gene) are unable to grow on medium containing the pyrimidine analog 5-fluoro-orotic acid, whereas ura3- mutants grow normally. This selection, based on the loss of orotidine-5'-phosphate decarboxylase activity seems applicable to a variety of eucaryotic and procaryotic cells.
    26 schema:genre research_article
    27 schema:inLanguage en
    28 schema:isAccessibleForFree false
    29 schema:isPartOf N5e7e8ebc08054fb189056817da1ebc08
    30 N8765ac3f900449ada224863a507a68ca
    31 sg:journal.1297380
    32 schema:name A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance
    33 schema:pagination 345-346
    34 schema:productId N12c2dd9767334b2e84d5cb165b36115f
    35 N1c6b8160551641019cca99b952d2ad1f
    36 N85b8b05efaa249639ab1e8da57cbc80e
    37 Nc67ad646c34141db867bf314c46e4321
    38 Ne8b3a362705f4381935f9d7af4b57e60
    39 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017841696
    40 https://doi.org/10.1007/bf00330984
    41 schema:sdDatePublished 2019-04-15T08:54
    42 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    43 schema:sdPublisher N42f9c7e9aab34a33a3fa4d29a1b11e35
    44 schema:url http://link.springer.com/10.1007/BF00330984
    45 sgo:license sg:explorer/license/
    46 sgo:sdDataset articles
    47 rdf:type schema:ScholarlyArticle
    48 N066c8f94556440b598b539b1906e054d rdf:first sg:person.01022533774.72
    49 rdf:rest N5d8c73cbebee419aa36d9cc43d00d3cf
    50 N12c2dd9767334b2e84d5cb165b36115f schema:name doi
    51 schema:value 10.1007/bf00330984
    52 rdf:type schema:PropertyValue
    53 N1c6b8160551641019cca99b952d2ad1f schema:name nlm_unique_id
    54 schema:value 0125036
    55 rdf:type schema:PropertyValue
    56 N42f9c7e9aab34a33a3fa4d29a1b11e35 schema:name Springer Nature - SN SciGraph project
    57 rdf:type schema:Organization
    58 N488d0ff4d6b14c50aa9caa778dfa7cac schema:name Laboratoire de Genetique Physiologique, Strasbourg, France
    59 rdf:type schema:Organization
    60 N5d8c73cbebee419aa36d9cc43d00d3cf rdf:first Na077909b322a491788bbc8bb20385d5b
    61 rdf:rest Nacf4f2091d3942c196a710582f53fa6f
    62 N5e7e8ebc08054fb189056817da1ebc08 schema:volumeNumber 197
    63 rdf:type schema:PublicationVolume
    64 N6fa62ff90cf54bcda2e7843027b95adb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    65 schema:name Orotidine-5'-Phosphate Decarboxylase
    66 rdf:type schema:DefinedTerm
    67 N85b8b05efaa249639ab1e8da57cbc80e schema:name dimensions_id
    68 schema:value pub.1017841696
    69 rdf:type schema:PropertyValue
    70 N8765ac3f900449ada224863a507a68ca schema:issueNumber 2
    71 rdf:type schema:PublicationIssue
    72 N87d48474a31146e4be66e827b2c1770e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    73 schema:name Fungal Proteins
    74 rdf:type schema:DefinedTerm
    75 N88dac35a8ab5454591dff8496e36333b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    76 schema:name Carboxy-Lyases
    77 rdf:type schema:DefinedTerm
    78 Na077909b322a491788bbc8bb20385d5b schema:affiliation N488d0ff4d6b14c50aa9caa778dfa7cac
    79 schema:familyName La Croute
    80 schema:givenName Francois
    81 rdf:type schema:Person
    82 Nacf4f2091d3942c196a710582f53fa6f rdf:first sg:person.015646367602.05
    83 rdf:rest rdf:nil
    84 Nb5960919adc747c3a6ea040e6af12306 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    85 schema:name Saccharomyces cerevisiae
    86 rdf:type schema:DefinedTerm
    87 Nc67ad646c34141db867bf314c46e4321 schema:name readcube_id
    88 schema:value 55027cc18d4e9284cdba93b27e0ee6087fbd52b27bf9ced3de01aac4cf5ea9d3
    89 rdf:type schema:PropertyValue
    90 Nd1e1baca550a4f97a29f4f06ac0e6c31 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    91 schema:name Orotic Acid
    92 rdf:type schema:DefinedTerm
    93 Ne8b3a362705f4381935f9d7af4b57e60 schema:name pubmed_id
    94 schema:value 6394957
    95 rdf:type schema:PropertyValue
    96 Nec6a791c85574e408cbafd2ba9863237 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    97 schema:name Microbiological Techniques
    98 rdf:type schema:DefinedTerm
    99 Nef8a023f0c3742a7b5ebe920d8663038 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    100 schema:name Drug Resistance, Microbial
    101 rdf:type schema:DefinedTerm
    102 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    103 schema:name Biological Sciences
    104 rdf:type schema:DefinedTerm
    105 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
    106 schema:name Genetics
    107 rdf:type schema:DefinedTerm
    108 sg:journal.1297380 schema:issn 1432-1874
    109 1617-4615
    110 schema:name Molecular Genetics and Genomics
    111 rdf:type schema:Periodical
    112 sg:person.01022533774.72 schema:affiliation https://www.grid.ac/institutes/grid.116068.8
    113 schema:familyName Boeke
    114 schema:givenName Jef D.
    115 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022533774.72
    116 rdf:type schema:Person
    117 sg:person.015646367602.05 schema:affiliation https://www.grid.ac/institutes/grid.116068.8
    118 schema:familyName Fink
    119 schema:givenName Gerald R.
    120 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015646367602.05
    121 rdf:type schema:Person
    122 sg:pub.10.1007/bf00277292 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001584443
    123 https://doi.org/10.1007/bf00277292
    124 rdf:type schema:CreativeWork
    125 sg:pub.10.1007/bf00382100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031295850
    126 https://doi.org/10.1007/bf00382100
    127 rdf:type schema:CreativeWork
    128 https://app.dimensions.ai/details/publication/pub.1074725931 schema:CreativeWork
    129 https://app.dimensions.ai/details/publication/pub.1077359010 schema:CreativeWork
    130 https://app.dimensions.ai/details/publication/pub.1080298936 schema:CreativeWork
    131 https://app.dimensions.ai/details/publication/pub.1080434314 schema:CreativeWork
    132 https://app.dimensions.ai/details/publication/pub.1081682266 schema:CreativeWork
    133 https://doi.org/10.1016/0076-6879(83)01016-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030230624
    134 rdf:type schema:CreativeWork
    135 https://doi.org/10.1016/0076-6879(83)01017-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008079849
    136 rdf:type schema:CreativeWork
    137 https://doi.org/10.1016/0378-1119(79)90004-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039235741
    138 rdf:type schema:CreativeWork
    139 https://doi.org/10.1016/0378-1119(84)90172-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000917632
    140 rdf:type schema:CreativeWork
    141 https://doi.org/10.1073/pnas.76.1.386 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010513873
    142 rdf:type schema:CreativeWork
    143 https://www.grid.ac/institutes/grid.116068.8 schema:alternateName Massachusetts Institute of Technology
    144 schema:name Massachusetts Institute of Technology and Whitehead Institute for Biomedical Research, 02142, Cambridge, Massachusetts, USA
    145 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...