Structural variability in the genome of phage ϕH of Halobacterium halobium View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1982-12

AUTHORS

Heinke Schnabel, Edgar Schramm, Ralf Schnabel, Wolfram Zillig

ABSTRACT

The partially circularly permuted, terminally redundant structure of the DNA of phage ϕH has been confirmed by a cleavage map for the restriction enzymes PstI, ClaI, BglII, HindIII, and, partially, BamHI. Six variants of phage ϕH have been isolated from 71 single plaques. Their genomes differ by several insertions, a deletion, and an inversion of a DNA segment with a minimal length of 11 kb. The inversion occurs with high frequency in variants carrying at the flanks of the invertible DNA in verted repeats of a 1.8 kb DNA element which shares sequence homology with the DNA of H. halobium and may be involved in the extreme variability of its genome. More... »

PAGES

370-377

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00330036

DOI

http://dx.doi.org/10.1007/bf00330036

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1032881945


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