Changes in T-DNA methylation and expression are associated with phenotypic variation and plant regeneration in a crown gall tumor line View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1984-11

AUTHORS

Richard M. Amasino, Ann L. T. Powell, Milton P. Gordon

ABSTRACT

Phenotypic variation of an octopine-type crown gall tumor line resulting from changes in the pattern of T-DNA methylation and expression is described. Variants that grow as unorganized callus always express T-DNA transcripts 1 and 2. In shoot-forming variants (teratomas) only T-DNA transcript 4 is expressed. This line also regenerates normal-appearing, rooted plants in which all T-DNA expression is suppressed. Tissues from these plants require phytohormones for growth in vitro. These plants are selffertile and transmit T-DNA through meiosis, and T-DNA suppression is maintained in the next generation. After treatment of regenerated plant tissue with 5-azacytidine, an inhibitor of DNA methylation, T-DNA transcription and phytohormone-independent tumorous growth resume. The T-DNA of cell lines in which T-DNA is not expressed is highly methylated, whereas the level of T-DNA methylation is reduced in 5-azacytidine treated cells that resume T-DNA expression and phytohormone-independent growth. The correlation between the degree of T-DNA methylation and the level of T-DNA expression indicates that hypermethylation is responsible for the suppression of T-DNA transcription. More... »

PAGES

437-446

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00329940

DOI

http://dx.doi.org/10.1007/bf00329940

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1037063138

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6084805


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0607", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Plant Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Azacitidine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Line", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression Regulation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Variation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Meiosis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Methylation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phenotype", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Plant Tumors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recombination, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rhizobium", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Microbiology, SC-42, University of Washington, 98195, Seattle, WA, USA", 
          "id": "http://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "Department of Microbiology, SC-42, University of Washington, 98195, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Amasino", 
        "givenName": "Richard M.", 
        "id": "sg:person.01125456525.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125456525.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biochemistry, SJ-70, University of Washington, 98195, Seattle, WA, USA", 
          "id": "http://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "Department of Biochemistry, SJ-70, University of Washington, 98195, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Powell", 
        "givenName": "Ann L. T.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Biochemistry, SJ-70, University of Washington, 98195, Seattle, WA, USA", 
          "id": "http://www.grid.ac/institutes/grid.34477.33", 
          "name": [
            "Department of Biochemistry, SJ-70, University of Washington, 98195, Seattle, WA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gordon", 
        "givenName": "Milton P.", 
        "id": "sg:person.0625643767.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625643767.99"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/292860a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024461091", 
          "https://doi.org/10.1038/292860a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4684-4493-3_16", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024795187", 
          "https://doi.org/10.1007/978-1-4684-4493-3_16"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00383526", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002496075", 
          "https://doi.org/10.1007/bf00383526"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00331085", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044783076", 
          "https://doi.org/10.1007/bf00331085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/304275a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052931975", 
          "https://doi.org/10.1038/304275a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01578595", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046059264", 
          "https://doi.org/10.1007/bf01578595"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/287359a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043453845", 
          "https://doi.org/10.1038/287359a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01075264", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022214242", 
          "https://doi.org/10.1007/bf01075264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/300752a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008470291", 
          "https://doi.org/10.1038/300752a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1984-11", 
    "datePublishedReg": "1984-11-01", 
    "description": "Phenotypic variation of an octopine-type crown gall tumor line resulting from changes in the pattern of T-DNA methylation and expression is described. Variants that grow as unorganized callus always express T-DNA transcripts 1 and 2. In shoot-forming variants (teratomas) only T-DNA transcript 4 is expressed. This line also regenerates normal-appearing, rooted plants in which all T-DNA expression is suppressed. Tissues from these plants require phytohormones for growth in vitro. These plants are selffertile and transmit T-DNA through meiosis, and T-DNA suppression is maintained in the next generation. After treatment of regenerated plant tissue with 5-azacytidine, an inhibitor of DNA methylation, T-DNA transcription and phytohormone-independent tumorous growth resume. The T-DNA of cell lines in which T-DNA is not expressed is highly methylated, whereas the level of T-DNA methylation is reduced in 5-azacytidine treated cells that resume T-DNA expression and phytohormone-independent growth. The correlation between the degree of T-DNA methylation and the level of T-DNA expression indicates that hypermethylation is responsible for the suppression of T-DNA transcription.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/bf00329940", 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2371635", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1297380", 
        "issn": [
          "1617-4615", 
          "1432-1874"
        ], 
        "name": "Molecular Genetics and Genomics", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "197"
      }
    ], 
    "keywords": [
      "T-DNA expression", 
      "T-DNA", 
      "phenotypic variation", 
      "phytohormone-independent growth", 
      "plant regeneration", 
      "DNA methylation", 
      "unorganized callus", 
      "plant tissues", 
      "methylation", 
      "transcript 4", 
      "plants", 
      "tumor lines", 
      "cell lines", 
      "growth resumes", 
      "transcript 1", 
      "transcription", 
      "expression", 
      "phytohormones", 
      "meiosis", 
      "variants", 
      "hypermethylation", 
      "growth", 
      "lines", 
      "callus", 
      "tissue", 
      "suppression", 
      "cells", 
      "inhibitors", 
      "variation", 
      "regeneration", 
      "next generation", 
      "levels", 
      "changes", 
      "patterns", 
      "generation", 
      "resume", 
      "treatment", 
      "correlation", 
      "degree"
    ], 
    "name": "Changes in T-DNA methylation and expression are associated with phenotypic variation and plant regeneration in a crown gall tumor line", 
    "pagination": "437-446", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1037063138"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf00329940"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "6084805"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf00329940", 
      "https://app.dimensions.ai/details/publication/pub.1037063138"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-10-01T06:27", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_153.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/bf00329940"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00329940'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00329940'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00329940'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00329940'


 

This table displays all metadata directly associated to this object as RDF triples.

201 TRIPLES      21 PREDICATES      86 URIs      68 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf00329940 schema:about N06862cb292af43fabf57e4baf07f4367
2 N1345f30729634a94a4eb03c73a03ea64
3 N2a44ccc4c7fe420da665218a534a9e7b
4 N49377a71953e46de8a7edf4c6d5e4284
5 N4d332bc14332444c94fc0adeb83dff55
6 N5fce2df98e1f46acb676105b2b408ca4
7 N67f4c2a85f4d41b3ac45f69655b90825
8 N7dd17eff334c470ab97639b407eca9e7
9 N907d0949fc6346f1b10c9c6d6b04a033
10 N91b9bcd723d842a2b01b3057b6237073
11 Nd07a11603d92425cad175aa98eeb67ff
12 anzsrc-for:06
13 anzsrc-for:0604
14 anzsrc-for:0607
15 schema:author N18e52d245438421e9d3cf4939f159832
16 schema:citation sg:pub.10.1007/978-1-4684-4493-3_16
17 sg:pub.10.1007/bf00331085
18 sg:pub.10.1007/bf00383526
19 sg:pub.10.1007/bf01075264
20 sg:pub.10.1007/bf01578595
21 sg:pub.10.1038/287359a0
22 sg:pub.10.1038/292860a0
23 sg:pub.10.1038/300752a0
24 sg:pub.10.1038/304275a0
25 schema:datePublished 1984-11
26 schema:datePublishedReg 1984-11-01
27 schema:description Phenotypic variation of an octopine-type crown gall tumor line resulting from changes in the pattern of T-DNA methylation and expression is described. Variants that grow as unorganized callus always express T-DNA transcripts 1 and 2. In shoot-forming variants (teratomas) only T-DNA transcript 4 is expressed. This line also regenerates normal-appearing, rooted plants in which all T-DNA expression is suppressed. Tissues from these plants require phytohormones for growth in vitro. These plants are selffertile and transmit T-DNA through meiosis, and T-DNA suppression is maintained in the next generation. After treatment of regenerated plant tissue with 5-azacytidine, an inhibitor of DNA methylation, T-DNA transcription and phytohormone-independent tumorous growth resume. The T-DNA of cell lines in which T-DNA is not expressed is highly methylated, whereas the level of T-DNA methylation is reduced in 5-azacytidine treated cells that resume T-DNA expression and phytohormone-independent growth. The correlation between the degree of T-DNA methylation and the level of T-DNA expression indicates that hypermethylation is responsible for the suppression of T-DNA transcription.
28 schema:genre article
29 schema:isAccessibleForFree false
30 schema:isPartOf N319084bf1abe405abf3ed6eb94630a95
31 N6f60bd1f2ab14a62a1eec5dfc79a74e6
32 sg:journal.1297380
33 schema:keywords DNA methylation
34 T-DNA
35 T-DNA expression
36 callus
37 cell lines
38 cells
39 changes
40 correlation
41 degree
42 expression
43 generation
44 growth
45 growth resumes
46 hypermethylation
47 inhibitors
48 levels
49 lines
50 meiosis
51 methylation
52 next generation
53 patterns
54 phenotypic variation
55 phytohormone-independent growth
56 phytohormones
57 plant regeneration
58 plant tissues
59 plants
60 regeneration
61 resume
62 suppression
63 tissue
64 transcript 1
65 transcript 4
66 transcription
67 treatment
68 tumor lines
69 unorganized callus
70 variants
71 variation
72 schema:name Changes in T-DNA methylation and expression are associated with phenotypic variation and plant regeneration in a crown gall tumor line
73 schema:pagination 437-446
74 schema:productId N59ccb59d26bd4d3a88a03cb189e441c6
75 N8a2ce7d42ddb4a0dbe939a23b69b2d61
76 Nce4c9fe2a3fe4f068318ad286a35792f
77 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037063138
78 https://doi.org/10.1007/bf00329940
79 schema:sdDatePublished 2022-10-01T06:27
80 schema:sdLicense https://scigraph.springernature.com/explorer/license/
81 schema:sdPublisher N3065528ed3574ea2bc0e1d1d055137a5
82 schema:url https://doi.org/10.1007/bf00329940
83 sgo:license sg:explorer/license/
84 sgo:sdDataset articles
85 rdf:type schema:ScholarlyArticle
86 N06862cb292af43fabf57e4baf07f4367 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Phenotype
88 rdf:type schema:DefinedTerm
89 N1345f30729634a94a4eb03c73a03ea64 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Gene Expression Regulation
91 rdf:type schema:DefinedTerm
92 N18e52d245438421e9d3cf4939f159832 rdf:first sg:person.01125456525.97
93 rdf:rest Ne31ea92d6444444e8d0b6e49c4096743
94 N1fb04e2ed5c940198afd1be4269b004f rdf:first sg:person.0625643767.99
95 rdf:rest rdf:nil
96 N2a44ccc4c7fe420da665218a534a9e7b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Meiosis
98 rdf:type schema:DefinedTerm
99 N3065528ed3574ea2bc0e1d1d055137a5 schema:name Springer Nature - SN SciGraph project
100 rdf:type schema:Organization
101 N319084bf1abe405abf3ed6eb94630a95 schema:issueNumber 3
102 rdf:type schema:PublicationIssue
103 N49377a71953e46de8a7edf4c6d5e4284 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Plant Tumors
105 rdf:type schema:DefinedTerm
106 N4d332bc14332444c94fc0adeb83dff55 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name DNA
108 rdf:type schema:DefinedTerm
109 N59ccb59d26bd4d3a88a03cb189e441c6 schema:name pubmed_id
110 schema:value 6084805
111 rdf:type schema:PropertyValue
112 N5fce2df98e1f46acb676105b2b408ca4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Recombination, Genetic
114 rdf:type schema:DefinedTerm
115 N67f4c2a85f4d41b3ac45f69655b90825 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Cell Line
117 rdf:type schema:DefinedTerm
118 N6f60bd1f2ab14a62a1eec5dfc79a74e6 schema:volumeNumber 197
119 rdf:type schema:PublicationVolume
120 N7dd17eff334c470ab97639b407eca9e7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
121 schema:name Genetic Variation
122 rdf:type schema:DefinedTerm
123 N8a2ce7d42ddb4a0dbe939a23b69b2d61 schema:name doi
124 schema:value 10.1007/bf00329940
125 rdf:type schema:PropertyValue
126 N907d0949fc6346f1b10c9c6d6b04a033 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Methylation
128 rdf:type schema:DefinedTerm
129 N91b9bcd723d842a2b01b3057b6237073 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Rhizobium
131 rdf:type schema:DefinedTerm
132 Nc595920a618d48e983acb685b085f5a3 schema:affiliation grid-institutes:grid.34477.33
133 schema:familyName Powell
134 schema:givenName Ann L. T.
135 rdf:type schema:Person
136 Nce4c9fe2a3fe4f068318ad286a35792f schema:name dimensions_id
137 schema:value pub.1037063138
138 rdf:type schema:PropertyValue
139 Nd07a11603d92425cad175aa98eeb67ff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Azacitidine
141 rdf:type schema:DefinedTerm
142 Ne31ea92d6444444e8d0b6e49c4096743 rdf:first Nc595920a618d48e983acb685b085f5a3
143 rdf:rest N1fb04e2ed5c940198afd1be4269b004f
144 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
145 schema:name Biological Sciences
146 rdf:type schema:DefinedTerm
147 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
148 schema:name Genetics
149 rdf:type schema:DefinedTerm
150 anzsrc-for:0607 schema:inDefinedTermSet anzsrc-for:
151 schema:name Plant Biology
152 rdf:type schema:DefinedTerm
153 sg:grant.2371635 http://pending.schema.org/fundedItem sg:pub.10.1007/bf00329940
154 rdf:type schema:MonetaryGrant
155 sg:journal.1297380 schema:issn 1432-1874
156 1617-4615
157 schema:name Molecular Genetics and Genomics
158 schema:publisher Springer Nature
159 rdf:type schema:Periodical
160 sg:person.01125456525.97 schema:affiliation grid-institutes:grid.34477.33
161 schema:familyName Amasino
162 schema:givenName Richard M.
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01125456525.97
164 rdf:type schema:Person
165 sg:person.0625643767.99 schema:affiliation grid-institutes:grid.34477.33
166 schema:familyName Gordon
167 schema:givenName Milton P.
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625643767.99
169 rdf:type schema:Person
170 sg:pub.10.1007/978-1-4684-4493-3_16 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024795187
171 https://doi.org/10.1007/978-1-4684-4493-3_16
172 rdf:type schema:CreativeWork
173 sg:pub.10.1007/bf00331085 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044783076
174 https://doi.org/10.1007/bf00331085
175 rdf:type schema:CreativeWork
176 sg:pub.10.1007/bf00383526 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002496075
177 https://doi.org/10.1007/bf00383526
178 rdf:type schema:CreativeWork
179 sg:pub.10.1007/bf01075264 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022214242
180 https://doi.org/10.1007/bf01075264
181 rdf:type schema:CreativeWork
182 sg:pub.10.1007/bf01578595 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046059264
183 https://doi.org/10.1007/bf01578595
184 rdf:type schema:CreativeWork
185 sg:pub.10.1038/287359a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043453845
186 https://doi.org/10.1038/287359a0
187 rdf:type schema:CreativeWork
188 sg:pub.10.1038/292860a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024461091
189 https://doi.org/10.1038/292860a0
190 rdf:type schema:CreativeWork
191 sg:pub.10.1038/300752a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008470291
192 https://doi.org/10.1038/300752a0
193 rdf:type schema:CreativeWork
194 sg:pub.10.1038/304275a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052931975
195 https://doi.org/10.1038/304275a0
196 rdf:type schema:CreativeWork
197 grid-institutes:grid.34477.33 schema:alternateName Department of Biochemistry, SJ-70, University of Washington, 98195, Seattle, WA, USA
198 Department of Microbiology, SC-42, University of Washington, 98195, Seattle, WA, USA
199 schema:name Department of Biochemistry, SJ-70, University of Washington, 98195, Seattle, WA, USA
200 Department of Microbiology, SC-42, University of Washington, 98195, Seattle, WA, USA
201 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...