Ontology type: schema:ScholarlyArticle
1990-07
AUTHORS ABSTRACTIn the testis of the trout, while no changes are apparent in myoid cells at any stage of maturation, Leydig cells display striking structural alterations when observed at different periods of the reproductive cycle. Spermiating testes contain fully differentiated Leydig cells. In regressed testes and those involved in spermatogenesis, poorly differentiated Leydig cells are mixed with cells ranging structurally from normal Leydig cells to fibroblast-like elements. After 3–4 days in culture the myoid cells/fibroblasts progressively acquire the ability to proliferate and then show a positive reaction for 3β-hydroxysteroid dehydrogenase. During the same period they undergo structural changes reflecting the emergence of a steroidogenic activity. These changes occur concomitantly with an increase in progestagen secretion. These data suggest that, in vivo, Leydig cells degenerate at the end of a cycle, being then replaced by fibroblastic precursor cells capable of division and differentiation into steroidogenic cells. More... »
PAGES133-144
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DOIhttp://dx.doi.org/10.1007/bf00329446
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