A further survey of the chromosomes in the Japanese View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1962-03

AUTHORS

Sajiro Makino, Yasumoto Kikuchi, Masao S. Sasaki, Motomichi Sasaki, Michihiro Yoshida

ABSTRACT

In the present study, information was obtained on the chromosomes in somatic cells derived from various organs of 135 foetuses, 1 to 7 months of age, and in germ-cells of two adult males. The chromosome counts were carried out on 2633 cells in primary cultures, on 3933 cells in subcultures and on 30 cells from directly squashed organs. In this total of 6596 cells studied, 6344 cells, or 96.18 per cent contained the normal complement of 46 chromosomes, regardless of sex, age, organ or experimental procedure. No evidence was detected for a chromosomal polymorphism in either somatic or germ-cells. In primary cultures from 127 foetuses two chromosomally abnormal individuals have been found. One contained in the majority of cells studied an obnormal complement of 45 chromosomes, a new, unusual karyotype of XY sex-chromosome constitution. The other showed cells with chromosome aberrations involving chromosome breaks, translocations and fragments in relatively high frequency. The sex-ratio (100 × N♂♂/N♀♀), observed on the basis of chromosomal diagnosis, was 96.67. More... »

PAGES

148-162

References to SciGraph publications

  • 1961-09. Distribution of Human Chromosome Counts in Relation to Age in NATURE
  • 1959-04. A Presumptive Human XXY/XX Mosaic in NATURE
  • 1956-11. The Chromosomes of Man in NATURE
  • 1959-12. THE HUMAN IDIOGRAM in HEREDITAS
  • 1956-05. THE CHROMOSOME NUMBER OF MAN in HEREDITAS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf00326568

    DOI

    http://dx.doi.org/10.1007/bf00326568

    DIMENSIONS

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    PUBMED

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