Acquired idiopathic generalized anhidrosis: a distinctive clinical syndrome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1988-09

AUTHORS

K. Murakami, G. Sobue, S. Terao, T. Mitsuma

ABSTRACT

The present study concerns a 28-year-old Japanese man with acquired generalized anhidrosis. The patient's ability to perspire was investigated in an artificial climate room maintained at 40 degrees C and 40% humidity. Although the body temperature rose to 38 degrees C, the patient did not sweat. Neither did sweating occur when the patient was given an intradermal injection of pilocarpine or nicotine. The serum IgE level was elevated. Atrophy and degeneration of the sweat glands, as well as infiltration by lymphocytes and mast cells around the sweat glands, were observed in skin biopsies. Anhidrosis in this patient was suggested to be the result of reduced function of the sweat glands themselves with possible underlying immune-mediated basis. More... »

PAGES

428-431

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00314488

DOI

http://dx.doi.org/10.1007/bf00314488

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034745784

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3065466


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