Lipid composition of myelin in multiple sclerosis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1976-06

AUTHORS

Mona E. Fewster, H. Hirono, J. F. Mead

ABSTRACT

Myelin was isolated from histologically normal white matter and plaques from MS patients and from white matter of neurologically normal controls. No difference was found in the total lipid content. There were no detectable deficits in MS myelin of phosphoglycerides, plasmalogens or sphingolipids. Gangliosides and lysolecithin were not detected. Analysis of the fatty aldehyde composition of the phosphoglycerides and the fatty acid composition of the cholesteryl esters, phosphoglycerides and sphingolipids did not show any differences between the normal and MS myelin. More... »

PAGES

119-131

References to SciGraph publications

  • 1964-12. Analytical fractionation of complex lipid mixtures: DEAE cellulose column chromatography combined with quantitative thin layer chromatography in JOURNAL OF THE AMERICAN OIL CHEMISTS' SOCIETY
  • 1965-05. Lipid analysis by quantitative thin-layer chromatography in JOURNAL OF THE AMERICAN OIL CHEMISTS' SOCIETY
  • 1967-08. Aetiology of Multiple Sclerosis in NATURE
  • 1960-08. Fractionation of fats, oils, and waxes on thin layers of silicic acid in JOURNAL OF THE AMERICAN OIL CHEMISTS' SOCIETY
  • 1972. The Biochemistry of Demyelination and Demyelinating Diseases in BIOCHEMICAL ASPECTS OF NERVOUS DISEASES
  • Identifiers

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    http://scigraph.springernature.com/pub.10.1007/bf00313273

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    http://dx.doi.org/10.1007/bf00313273

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/60471


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