Cone cells fail to develop normally in transgenic mice showing ablation of rod photoreceptor cells View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1994-01

AUTHORS

Jiro Usukura, Wilson Khoo, Thoru Abe, Martin L. Breitman, Toshimichi Shinohara

ABSTRACT

Transgenic mice were derived containing the cytotoxic dt-alpha gene driven by opsin promoter sequences. Mice expressing this construct showed progressive degeneration of rod photoreceptor cells commencing at birth, with obvious depletion of such cells by postnatal day 7. Ablation of rod photoreceptor cells in the transgenic retina was accompanied by the failure of developing cone cells to elaborate outer segments, although all other aspects of cone cell cytodifferentiation appeared normal. The results suggest that the 1.0-kb opsin promoter segment contains rod cell type specificity and that cone cells require maturation of rod cells to complete the late stages of their terminal differentiation and for their maintenance and cellular integrity. More... »

PAGES

79-90

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00305377

DOI

http://dx.doi.org/10.1007/bf00305377

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018288908

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8118849


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1109", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Neurosciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Differentiation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diphtheria Toxin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Eye Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Transgenic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Microscopy, Electron", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Promoter Regions, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recombinant Fusion Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retina", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retinal Cone Photoreceptor Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retinal Degeneration", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retinal Rod Photoreceptor Cells", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rod Opsins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Synapses", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Nagoya University", 
          "id": "https://www.grid.ac/institutes/grid.27476.30", 
          "name": [
            "Department of Anatomy, Nagoya University School of Medicine, Tsurumai, Nagoya, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Usukura", 
        "givenName": "Jiro", 
        "id": "sg:person.07653424461.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07653424461.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Division of Molecular and Developmental Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, M5G 1X5, Toronto, Ontario, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Khoo", 
        "givenName": "Wilson", 
        "id": "sg:person.01062373470.30", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062373470.30"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, National Institute of Health, Bg. 6, Rm. 327, Bethesda, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Abe", 
        "givenName": "Thoru", 
        "id": "sg:person.01130506670.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130506670.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Toronto", 
          "id": "https://www.grid.ac/institutes/grid.17063.33", 
          "name": [
            "Division of Molecular and Developmental Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, M5G 1X5, Toronto, Ontario, Canada", 
            "Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario, Canada"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Breitman", 
        "givenName": "Martin L.", 
        "id": "sg:person.0675152442.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675152442.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, National Institute of Health, Bg. 6, Rm. 327, Bethesda, Maryland, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shinohara", 
        "givenName": "Toshimichi", 
        "id": "sg:person.014507043522.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014507043522.12"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1002/jez.1401890309", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000966474"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jez.1401890309", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000966474"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0012-1606(86)90319-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003815587"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cne.901880205", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007977039"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0896-6273(91)90355-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008343408"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/328131a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010770970", 
          "https://doi.org/10.1038/328131a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.81.15.4851", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016622112"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00519723", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016667250", 
          "https://doi.org/10.1007/bf00519723"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00519723", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016667250", 
          "https://doi.org/10.1007/bf00519723"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0896-6273(90)90136-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017413193"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0014-4835(87)80061-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017492287"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0278-4327(87)90017-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017683611"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0278-4327(87)90017-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017683611"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4684-4685-2_4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020980191", 
          "https://doi.org/10.1007/978-1-4684-4685-2_4"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4899-6726-8_2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023163309", 
          "https://doi.org/10.1007/978-1-4899-6726-8_2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cne.901560108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025613564"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-2836(75)80083-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033296365"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/347677a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033528083", 
          "https://doi.org/10.1038/347677a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1989.tb14549.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034478820"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.8.4.1570", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046163457"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0896-6273(91)90356-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046660821"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/aja.1001330205", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048101472"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-065x.1987.tb00527.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052486107"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.88.19.8322", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052593101"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.3685993", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062620745"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079762076", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1994-01", 
    "datePublishedReg": "1994-01-01", 
    "description": "Transgenic mice were derived containing the cytotoxic dt-alpha gene driven by opsin promoter sequences. Mice expressing this construct showed progressive degeneration of rod photoreceptor cells commencing at birth, with obvious depletion of such cells by postnatal day 7. Ablation of rod photoreceptor cells in the transgenic retina was accompanied by the failure of developing cone cells to elaborate outer segments, although all other aspects of cone cell cytodifferentiation appeared normal. The results suggest that the 1.0-kb opsin promoter segment contains rod cell type specificity and that cone cells require maturation of rod cells to complete the late stages of their terminal differentiation and for their maintenance and cellular integrity.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf00305377", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1019675", 
        "issn": [
          "0302-766X", 
          "1432-0878"
        ], 
        "name": "Cell and Tissue Research", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "275"
      }
    ], 
    "name": "Cone cells fail to develop normally in transgenic mice showing ablation of rod photoreceptor cells", 
    "pagination": "79-90", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf00305377"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "5723a97db4d72091d7185de662455e90343b7b626adee1413949db838af7da8a"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1018288908"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0417625"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8118849"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf00305377", 
      "https://app.dimensions.ai/details/publication/pub.1018288908"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T08:50", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000374_0000000374/records_119732_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF00305377"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00305377'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00305377'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00305377'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00305377'


 

This table displays all metadata directly associated to this object as RDF triples.

240 TRIPLES      21 PREDICATES      67 URIs      36 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf00305377 schema:about N04c9f6a0876f47aa87859dba49ca70b7
2 N1a67bfe517f047a3b8add44a17b481c5
3 N1bc407d65e6e48f28aaf3abeca507998
4 N2547206436cd4f599a19a4d2e44e0f48
5 N498d121d3cc14a2980971b7b4b2415b6
6 N51a5831988364467b8baf0d7c222518c
7 N5c110cddcc8041a9a1e3597ced2c27c9
8 N9fd93c8078de4e6c8069db2c17274ba8
9 Na945b66cbd634de397ed2ef2ea05c1dd
10 Nb89a7bfbdfe44aefaf0bc48d20fc3f58
11 Nb8ff1f11473b43a2bf6a3fd2cbc25f6c
12 Nba65354e46704c129cdf331e3f0e1e67
13 Nbf16ccc2858441f29f1899264bfd04f0
14 Ne37653f9a61e4362b57c82a50c7290b8
15 Nf020de760d4247eca44e36dc6d14a6bf
16 anzsrc-for:11
17 anzsrc-for:1109
18 schema:author Nbf4b641002474a7284638ca88c118487
19 schema:citation sg:pub.10.1007/978-1-4684-4685-2_4
20 sg:pub.10.1007/978-1-4899-6726-8_2
21 sg:pub.10.1007/bf00519723
22 sg:pub.10.1038/328131a0
23 sg:pub.10.1038/347677a0
24 https://app.dimensions.ai/details/publication/pub.1079762076
25 https://doi.org/10.1002/aja.1001330205
26 https://doi.org/10.1002/cne.901560108
27 https://doi.org/10.1002/cne.901880205
28 https://doi.org/10.1002/jez.1401890309
29 https://doi.org/10.1016/0012-1606(86)90319-2
30 https://doi.org/10.1016/0278-4327(87)90017-4
31 https://doi.org/10.1016/0896-6273(90)90136-4
32 https://doi.org/10.1016/0896-6273(91)90355-4
33 https://doi.org/10.1016/0896-6273(91)90356-5
34 https://doi.org/10.1016/s0014-4835(87)80061-1
35 https://doi.org/10.1016/s0022-2836(75)80083-0
36 https://doi.org/10.1073/pnas.81.15.4851
37 https://doi.org/10.1073/pnas.88.19.8322
38 https://doi.org/10.1111/j.1432-1033.1989.tb14549.x
39 https://doi.org/10.1111/j.1600-065x.1987.tb00527.x
40 https://doi.org/10.1126/science.3685993
41 https://doi.org/10.1128/mcb.8.4.1570
42 schema:datePublished 1994-01
43 schema:datePublishedReg 1994-01-01
44 schema:description Transgenic mice were derived containing the cytotoxic dt-alpha gene driven by opsin promoter sequences. Mice expressing this construct showed progressive degeneration of rod photoreceptor cells commencing at birth, with obvious depletion of such cells by postnatal day 7. Ablation of rod photoreceptor cells in the transgenic retina was accompanied by the failure of developing cone cells to elaborate outer segments, although all other aspects of cone cell cytodifferentiation appeared normal. The results suggest that the 1.0-kb opsin promoter segment contains rod cell type specificity and that cone cells require maturation of rod cells to complete the late stages of their terminal differentiation and for their maintenance and cellular integrity.
45 schema:genre research_article
46 schema:inLanguage en
47 schema:isAccessibleForFree false
48 schema:isPartOf N59830ebe94f446019b0f12f150146d6e
49 N5b80bd3457a2454d8ebc492be3477d5b
50 sg:journal.1019675
51 schema:name Cone cells fail to develop normally in transgenic mice showing ablation of rod photoreceptor cells
52 schema:pagination 79-90
53 schema:productId N14defe9f8c22417c91cf478665355c3b
54 N272a85af50e54473a73142b634f34d0e
55 N56a262119a9445ca94b91f61edccfbaf
56 Nbb7cd89521b840c0b98dece0ef3fdcb0
57 Nfb07b4219e56451a8464882b33783cfc
58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018288908
59 https://doi.org/10.1007/bf00305377
60 schema:sdDatePublished 2019-04-15T08:50
61 schema:sdLicense https://scigraph.springernature.com/explorer/license/
62 schema:sdPublisher N5e0e22f516284000918eb1b655206123
63 schema:url http://link.springer.com/10.1007/BF00305377
64 sgo:license sg:explorer/license/
65 sgo:sdDataset articles
66 rdf:type schema:ScholarlyArticle
67 N04c9f6a0876f47aa87859dba49ca70b7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
68 schema:name Cell Differentiation
69 rdf:type schema:DefinedTerm
70 N0c14e84050d840d49ba91a4b7b697dd5 schema:name Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, National Institute of Health, Bg. 6, Rm. 327, Bethesda, Maryland, USA
71 rdf:type schema:Organization
72 N0c449609dcb7490d8a2bfb6f8252d20f schema:name Division of Molecular and Developmental Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, M5G 1X5, Toronto, Ontario, Canada
73 rdf:type schema:Organization
74 N14defe9f8c22417c91cf478665355c3b schema:name readcube_id
75 schema:value 5723a97db4d72091d7185de662455e90343b7b626adee1413949db838af7da8a
76 rdf:type schema:PropertyValue
77 N17ca5d1e521740e284b38c6d1a77fff5 rdf:first sg:person.01062373470.30
78 rdf:rest Nf051352e1e00466991c9264a619a142e
79 N1a67bfe517f047a3b8add44a17b481c5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Mice
81 rdf:type schema:DefinedTerm
82 N1bc407d65e6e48f28aaf3abeca507998 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Rod Opsins
84 rdf:type schema:DefinedTerm
85 N2547206436cd4f599a19a4d2e44e0f48 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Mice, Transgenic
87 rdf:type schema:DefinedTerm
88 N272a85af50e54473a73142b634f34d0e schema:name nlm_unique_id
89 schema:value 0417625
90 rdf:type schema:PropertyValue
91 N498d121d3cc14a2980971b7b4b2415b6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Animals
93 rdf:type schema:DefinedTerm
94 N51a5831988364467b8baf0d7c222518c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Synapses
96 rdf:type schema:DefinedTerm
97 N56a262119a9445ca94b91f61edccfbaf schema:name dimensions_id
98 schema:value pub.1018288908
99 rdf:type schema:PropertyValue
100 N59830ebe94f446019b0f12f150146d6e schema:issueNumber 1
101 rdf:type schema:PublicationIssue
102 N5b80bd3457a2454d8ebc492be3477d5b schema:volumeNumber 275
103 rdf:type schema:PublicationVolume
104 N5c110cddcc8041a9a1e3597ced2c27c9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Diphtheria Toxin
106 rdf:type schema:DefinedTerm
107 N5e0e22f516284000918eb1b655206123 schema:name Springer Nature - SN SciGraph project
108 rdf:type schema:Organization
109 N72a20a8dd2464883878ae1ff649761c2 rdf:first sg:person.0675152442.48
110 rdf:rest Nb51bea1f9ef64bb48d08c4961503847a
111 N9fd93c8078de4e6c8069db2c17274ba8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Microscopy, Electron
113 rdf:type schema:DefinedTerm
114 Na945b66cbd634de397ed2ef2ea05c1dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Retinal Rod Photoreceptor Cells
116 rdf:type schema:DefinedTerm
117 Nab03d173ed8b4acab682066684a30042 schema:name Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, National Institute of Health, Bg. 6, Rm. 327, Bethesda, Maryland, USA
118 rdf:type schema:Organization
119 Nb51bea1f9ef64bb48d08c4961503847a rdf:first sg:person.014507043522.12
120 rdf:rest rdf:nil
121 Nb89a7bfbdfe44aefaf0bc48d20fc3f58 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Recombinant Fusion Proteins
123 rdf:type schema:DefinedTerm
124 Nb8ff1f11473b43a2bf6a3fd2cbc25f6c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Retinal Cone Photoreceptor Cells
126 rdf:type schema:DefinedTerm
127 Nba65354e46704c129cdf331e3f0e1e67 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Retina
129 rdf:type schema:DefinedTerm
130 Nbb7cd89521b840c0b98dece0ef3fdcb0 schema:name doi
131 schema:value 10.1007/bf00305377
132 rdf:type schema:PropertyValue
133 Nbf16ccc2858441f29f1899264bfd04f0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
134 schema:name Promoter Regions, Genetic
135 rdf:type schema:DefinedTerm
136 Nbf4b641002474a7284638ca88c118487 rdf:first sg:person.07653424461.17
137 rdf:rest N17ca5d1e521740e284b38c6d1a77fff5
138 Ne37653f9a61e4362b57c82a50c7290b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
139 schema:name Retinal Degeneration
140 rdf:type schema:DefinedTerm
141 Nf020de760d4247eca44e36dc6d14a6bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Eye Proteins
143 rdf:type schema:DefinedTerm
144 Nf051352e1e00466991c9264a619a142e rdf:first sg:person.01130506670.12
145 rdf:rest N72a20a8dd2464883878ae1ff649761c2
146 Nfb07b4219e56451a8464882b33783cfc schema:name pubmed_id
147 schema:value 8118849
148 rdf:type schema:PropertyValue
149 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
150 schema:name Medical and Health Sciences
151 rdf:type schema:DefinedTerm
152 anzsrc-for:1109 schema:inDefinedTermSet anzsrc-for:
153 schema:name Neurosciences
154 rdf:type schema:DefinedTerm
155 sg:journal.1019675 schema:issn 0302-766X
156 1432-0878
157 schema:name Cell and Tissue Research
158 rdf:type schema:Periodical
159 sg:person.01062373470.30 schema:affiliation N0c449609dcb7490d8a2bfb6f8252d20f
160 schema:familyName Khoo
161 schema:givenName Wilson
162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01062373470.30
163 rdf:type schema:Person
164 sg:person.01130506670.12 schema:affiliation N0c14e84050d840d49ba91a4b7b697dd5
165 schema:familyName Abe
166 schema:givenName Thoru
167 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01130506670.12
168 rdf:type schema:Person
169 sg:person.014507043522.12 schema:affiliation Nab03d173ed8b4acab682066684a30042
170 schema:familyName Shinohara
171 schema:givenName Toshimichi
172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014507043522.12
173 rdf:type schema:Person
174 sg:person.0675152442.48 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
175 schema:familyName Breitman
176 schema:givenName Martin L.
177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0675152442.48
178 rdf:type schema:Person
179 sg:person.07653424461.17 schema:affiliation https://www.grid.ac/institutes/grid.27476.30
180 schema:familyName Usukura
181 schema:givenName Jiro
182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07653424461.17
183 rdf:type schema:Person
184 sg:pub.10.1007/978-1-4684-4685-2_4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020980191
185 https://doi.org/10.1007/978-1-4684-4685-2_4
186 rdf:type schema:CreativeWork
187 sg:pub.10.1007/978-1-4899-6726-8_2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023163309
188 https://doi.org/10.1007/978-1-4899-6726-8_2
189 rdf:type schema:CreativeWork
190 sg:pub.10.1007/bf00519723 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016667250
191 https://doi.org/10.1007/bf00519723
192 rdf:type schema:CreativeWork
193 sg:pub.10.1038/328131a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010770970
194 https://doi.org/10.1038/328131a0
195 rdf:type schema:CreativeWork
196 sg:pub.10.1038/347677a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033528083
197 https://doi.org/10.1038/347677a0
198 rdf:type schema:CreativeWork
199 https://app.dimensions.ai/details/publication/pub.1079762076 schema:CreativeWork
200 https://doi.org/10.1002/aja.1001330205 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048101472
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1002/cne.901560108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025613564
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1002/cne.901880205 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007977039
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1002/jez.1401890309 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000966474
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1016/0012-1606(86)90319-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003815587
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/0278-4327(87)90017-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017683611
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1016/0896-6273(90)90136-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017413193
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1016/0896-6273(91)90355-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008343408
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1016/0896-6273(91)90356-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046660821
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1016/s0014-4835(87)80061-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017492287
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1016/s0022-2836(75)80083-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033296365
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1073/pnas.81.15.4851 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016622112
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1073/pnas.88.19.8322 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052593101
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1111/j.1432-1033.1989.tb14549.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034478820
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1111/j.1600-065x.1987.tb00527.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1052486107
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1126/science.3685993 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062620745
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1128/mcb.8.4.1570 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046163457
233 rdf:type schema:CreativeWork
234 https://www.grid.ac/institutes/grid.17063.33 schema:alternateName University of Toronto
235 schema:name Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario, Canada
236 Division of Molecular and Developmental Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, M5G 1X5, Toronto, Ontario, Canada
237 rdf:type schema:Organization
238 https://www.grid.ac/institutes/grid.27476.30 schema:alternateName Nagoya University
239 schema:name Department of Anatomy, Nagoya University School of Medicine, Tsurumai, Nagoya, Japan
240 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...