Electron microscopical analysis of Drosophila polytene chromosomes View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1989-03

AUTHORS

V. F. Semeshin, S. A. Demakov, M. Perez Alonso, E. S. Belyaeva, J. J. Bonner, I. F. Zhimulev

ABSTRACT

An electron microscopical (EM) analysis was performed on regions of polytene chromosomes which contained DNA segments of different genetic composition, inserted by P element-mediated transformation into the Drosophila melanogaster genome. In seven of ten regions examined, containing insertions of the hsp28-ry, hsp70-Adh, ryhsp 70-beta-gal genes and of the ry gene tetramer, new bands appeared. Lack of new bands in three other strains is apparently connected with the fusion of the inserted material to preexisting bands. The new bands do not differ morphologically from the usual bands of polytene chromosomes, and their formation is likely due to predominant insertion of DNA segments into interbands. Among the constructs examined, the minimal length of a DNA segment which appears as a new band is about 5 kb; the DNA packing ratio in the new bands varies from 30 to 50. Activation of the inserted genes by heat shock has enabled us to observe the puffing characteristics of new bands. A sequence of some one kb forms a large interband, or micropuff; the puff size is correlated with the length of the genes being activated. If a DNA segment contains a single gene, then its activation causes the decompaction of the whole band; however, when a DNA segment consists of two genes and the promoter element of the activated gene is positioned in the middle of the sequence, the band splits and only part is decompacted and puffed. The DNA packing ratio in the puffs is 1.4-3.5. The subsequent deletion of the hsp70 promoter but retention of 23, 59, and 73 by from the transcription start points leads to failure of puff formation. In all the transformed sites an increase in the total length of the interbands adjacent to the insert as compared with the initial interband was observed. This increase appears to be due to decompaction of the P element DAN flanking the inserted segments. It is shown that a DNA segment, consisting of four tandemly repeated ry gene copies and interspersed by material which includes P DNA, forms a complex of loose chromatin in which, however, four bands can be resolved. We also observed a lengthening of interband regions containing only the P element sequence itself. Insertion of the complete 2.9 kb P element into the large single 10A1-2 bound of the X chromosome (an insertion in the region approximately 10 kb to the right of the v gene) causes splitting of the band into two parts and formation of a new interband.(ABSTRACT TRUNCATED AT 400 WORDS) More... »

PAGES

396-412

References to SciGraph publications

  • 1975. The Puffing Activities of the Salivary Gland Chromosomes in INVERTEBRATES OF GENETIC INTEREST
  • 1984-11. The arrangement of transposable elements in the polytene chromosomes of Drosophila melanogaster in CHROMOSOMA
  • 1974-01. Proposals to the problem of structural and functional organization of polytene chromosomes in THEORETICAL AND APPLIED GENETICS
  • 1973-09. Cytogenetic Fine Structure and Chromosomal Localization of the White Gene in Drosophila melanogaster in NATURE
  • 1974-03. Comparative study of the function of polytene chromosomes in laboratory stocks of Drosophila melanogaster and the l(3)tl mutant (lethal tumorous larvae) in CHROMOSOMA
  • 1980-03. Electron microscopic analysis of the banding pattern in the salivary gland chromosomes of Drosophila melanogaster. Division 1 and 2 of X in HEREDITAS
  • 1979-01. Electron microscope autoradiographic study on transcriptional activity of Drosophila melanogaster polytene chromosomes in CHROMOSOMA
  • 1971-11. General Model for the Chromosomes of Higher Organisms in NATURE
  • 1982-09. Volume of chromatin fibers in interbands and bands of polytene chromosomes in HEREDITAS
  • 1984-09. Electron microscopic map of divisions 61, 62, and 63 of the salivary gland 3L chromosome in Drosophila melanogaster in CHROMOSOMA
  • 1985-01. Electron microscopical analysis of Drosophila polytene chromosomes in CHROMOSOMA
  • 1985-01. Electron microscopical analysis of Drosophila polytene chromosomes in CHROMOSOMA
  • 1987-07. Cytogenetic analysis of region 2B3-4-2B11 of the X-chromosome of Drosophila melanogaster in CHROMOSOMA
  • 1970-03. Polytene chromosome structure at the submicroscopic level in CHROMOSOMA
  • 1981-03. Fine cytogenetical analysis of the band 10a1-2 and the adjoining regions in the Drosophila melanogaster X chromosome in CHROMOSOMA
  • 1986-06. Electron microscopical analysis of Drosophila polytene chromosomes in CHROMOSOMA
  • 1983-06. Electron microscopic analysis of the banding pattern in the salivary gland chromosomes of Drosophila melanogaster. Divisions 6 through 10 of X in HEREDITAS
  • 1981-03. Fine cytogenetical analysis of the band 10A1-2 and the adjoining regions in the Drosophila melanogaster X chromosome in CHROMOSOMA
  • 1982-12. Electron microscopical analysis of Drosophila polytene chromosomes in CHROMOSOMA
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf00292767

    DOI

    http://dx.doi.org/10.1007/bf00292767

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1036451963

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/2541983


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