Localisation du gène phosphoglycolate phosphatase (PGP) sur le chromosome 16 par l'hybridation cellulaire interspecifique View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1979-10

AUTHORS

Dominique Weil, Nguyen Van Cong, Catherine Finaz, Marie-Sylvie Gross, Chantal Cochet, J. de Grouchy, J. Frézal

ABSTRACT

Eight primary man-mouse (C11D/TK-) hybrids, twenty three primary and seven secondary man-hamster (CH/HGPRT-) were analyzed for human phosphoglycolate phosphatase (PGP) and for human chromosomes. The following results were obtained: 1. A positive correlation is observed between the chromosome 16 and PGP. 15 hybrids are chr.16+PGP+, 14 hybrids are chr.16-PGP- and 4 hybrids are chr.16-PGP+. 2. The percentage of dissociation between PGP and the chr.16 is low (12%) in comparison with the high percentage of dissociation between PGP and the other autosomes (between 37% and 65%). 3. Excepted the chromosome 16, the other autosomes are observed in hybrids PGP-. These different results indicate the localization of the gene for human PGP on the chromosome 16. The dissociation results chr.16-PGP+ are explained by the breakage of the chr.16 in the hybrids. More... »

PAGES

139-145

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00287167

DOI

http://dx.doi.org/10.1007/bf00287167

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1047837930

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/229074


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