The genetics of dopa decarboxylase in Drosophila melanogaster View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-06

AUTHORS

Theodore R. F. Wright, Wolfgang Beermann, J. Lawrence Marsh, Clifton P. Bishop, Ruth Steward, Bruce C. Black, Anne D. Tomsett, Eileen Y. Wright

ABSTRACT

Of 204 mutations located in the 8-12 band Df(2L)130 region, 37B9-C1,2;37D1-2, 199 have been assigned to twelve lethal genes and one visible gene (hook). The 13 genes are not evenly distributed. Twelve, (possibly all thirteen) are in the seven band region 37B10-C4 giving a gene-to-band ratio of almost two. Only one gene, 1(2)37Cf, may be in the four band region 37C5-7, and none are localized in band 37D1. In situ hybridization places the dopa decarboxylase structural gene, Ddc, in or very close to band 37C1,2 (Hirsh and Davidson, 1981). The chi methyl dopa hypersensitive gene, 1(2) and, is 0.002 map units distal to Ddc. Df(2L)VA17, 37C1,2; 37F5-38A1 may actually break in the 37C1,2 singlet. It places six genes, hook, 1(2) and, and four lethal genes, in a maximum of five bands, 37B10, 11, 12, 13 and perhaps part of the 37C1,2 singlet and localizes six genes, Ddc plus five lethal genes, in a maximum of three bands; probably part of the 37C1,2 singlet plus bands, C3, and C4. Wild type activity of five of twelve lethal genes is necessary for female fertility. --Band 37C5 puffs at the time of pupariation; Puff Stages 8-10. Twelve of eighteen alleles of 1(2)37Cf have been examined as heterozygotes over CyO and none affect the appearance of a homozygous 37C5 puff. --Of the 204 mutations considered here only one Ddcpl, affects the function of more than one gene. It eliminates Ddc+ and 1(2)37Ca+ function and at 30 degrees C reduces 1(2)37Ce+ function. It is not a deficiency but could be a polar mutant. More... »

PAGES

45-58

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00286015

DOI

http://dx.doi.org/10.1007/bf00286015

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003463670

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6790250


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aromatic-L-Amino-Acid Decarboxylases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosome Mapping", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dopa Decarboxylase", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drosophila melanogaster", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ethyl Methanesulfonate", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes, Lethal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infertility, Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutagens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Virginia", 
          "id": "https://www.grid.ac/institutes/grid.27755.32", 
          "name": [
            "Department of Biology, University of Virginia, 22903, Charlottesville, VA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wright", 
        "givenName": "Theodore R. F.", 
        "id": "sg:person.063415164.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.063415164.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Max Planck Institute for Biology", 
          "id": "https://www.grid.ac/institutes/grid.419580.1", 
          "name": [
            "Max Planck Institut f\u00fcr Biologie, T\u00fcbingen, Federal Republic of Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Beermann", 
        "givenName": "Wolfgang", 
        "id": "sg:person.075355426.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.075355426.22"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Virginia", 
          "id": "https://www.grid.ac/institutes/grid.27755.32", 
          "name": [
            "Department of Biology, University of Virginia, 22903, Charlottesville, VA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Marsh", 
        "givenName": "J. Lawrence", 
        "id": "sg:person.010150652252.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010150652252.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Virginia", 
          "id": "https://www.grid.ac/institutes/grid.27755.32", 
          "name": [
            "Department of Biology, University of Virginia, 22903, Charlottesville, VA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bishop", 
        "givenName": "Clifton P.", 
        "id": "sg:person.01142563167.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142563167.91"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Virginia", 
          "id": "https://www.grid.ac/institutes/grid.27755.32", 
          "name": [
            "Department of Biology, University of Virginia, 22903, Charlottesville, VA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Steward", 
        "givenName": "Ruth", 
        "id": "sg:person.014541275651.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014541275651.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Virginia", 
          "id": "https://www.grid.ac/institutes/grid.27755.32", 
          "name": [
            "Department of Biology, University of Virginia, 22903, Charlottesville, VA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Black", 
        "givenName": "Bruce C.", 
        "id": "sg:person.0625443547.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625443547.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Virginia", 
          "id": "https://www.grid.ac/institutes/grid.27755.32", 
          "name": [
            "Department of Biology, University of Virginia, 22903, Charlottesville, VA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tomsett", 
        "givenName": "Anne D.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Virginia", 
          "id": "https://www.grid.ac/institutes/grid.27755.32", 
          "name": [
            "Department of Biology, University of Virginia, 22903, Charlottesville, VA, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wright", 
        "givenName": "Eileen Y.", 
        "id": "sg:person.0601520667.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601520667.38"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf00269084", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005381898", 
          "https://doi.org/10.1007/bf00269084"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00269084", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005381898", 
          "https://doi.org/10.1007/bf00269084"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.77.7.4175", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006530737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0091-679x(08)60727-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008933776"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.1.6.475", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015124687"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00308501", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016404862", 
          "https://doi.org/10.1007/bf00308501"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00308501", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016404862", 
          "https://doi.org/10.1007/bf00308501"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00268674", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017196477", 
          "https://doi.org/10.1007/bf00268674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00268674", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017196477", 
          "https://doi.org/10.1007/bf00268674"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/287795a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017279186", 
          "https://doi.org/10.1038/287795a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1601-5223.1979.tb01635.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018731393", 
          "https://doi.org/10.1111/j.1601-5223.1979.tb01635.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0305-0491(72)90241-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020597364"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0305-0491(72)90241-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020597364"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-540-37164-9_5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026333918", 
          "https://doi.org/10.1007/978-3-540-37164-9_5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/dvg.1020020302", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027147433"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/dvg.1020020302", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027147433"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00332339", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036627089", 
          "https://doi.org/10.1007/bf00332339"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00332339", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036627089", 
          "https://doi.org/10.1007/bf00332339"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/2141159b0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041317461", 
          "https://doi.org/10.1038/2141159b0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/2141159b0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041317461", 
          "https://doi.org/10.1038/2141159b0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/b978-0-12-068350-5.50023-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041976776"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00484734", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045527525", 
          "https://doi.org/10.1007/bf00484734"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00484734", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045527525", 
          "https://doi.org/10.1007/bf00484734"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0012-1606(80)90412-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047941710"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00292637", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050513478", 
          "https://doi.org/10.1007/bf00292637"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00292637", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050513478", 
          "https://doi.org/10.1007/bf00292637"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081470708", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081557428", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082728636", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082728647", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jhered.a105104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083483929"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1981-06", 
    "datePublishedReg": "1981-06-01", 
    "description": "Of 204 mutations located in the 8-12 band Df(2L)130 region, 37B9-C1,2;37D1-2, 199 have been assigned to twelve lethal genes and one visible gene (hook). The 13 genes are not evenly distributed. Twelve, (possibly all thirteen) are in the seven band region 37B10-C4 giving a gene-to-band ratio of almost two. Only one gene, 1(2)37Cf, may be in the four band region 37C5-7, and none are localized in band 37D1. In situ hybridization places the dopa decarboxylase structural gene, Ddc, in or very close to band 37C1,2 (Hirsh and Davidson, 1981). The chi methyl dopa hypersensitive gene, 1(2) and, is 0.002 map units distal to Ddc. Df(2L)VA17, 37C1,2; 37F5-38A1 may actually break in the 37C1,2 singlet. It places six genes, hook, 1(2) and, and four lethal genes, in a maximum of five bands, 37B10, 11, 12, 13 and perhaps part of the 37C1,2 singlet and localizes six genes, Ddc plus five lethal genes, in a maximum of three bands; probably part of the 37C1,2 singlet plus bands, C3, and C4. Wild type activity of five of twelve lethal genes is necessary for female fertility. --Band 37C5 puffs at the time of pupariation; Puff Stages 8-10. Twelve of eighteen alleles of 1(2)37Cf have been examined as heterozygotes over CyO and none affect the appearance of a homozygous 37C5 puff. --Of the 204 mutations considered here only one Ddcpl, affects the function of more than one gene. It eliminates Ddc+ and 1(2)37Ca+ function and at 30 degrees C reduces 1(2)37Ce+ function. It is not a deficiency but could be a polar mutant.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf00286015", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2508739", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1312277", 
        "issn": [
          "0009-5915", 
          "1432-0886"
        ], 
        "name": "Chromosoma", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "83"
      }
    ], 
    "name": "The genetics of dopa decarboxylase in Drosophila melanogaster", 
    "pagination": "45-58", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf00286015"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "107ff559411d9f8c07ad33f8688a62fe3268ca66b1f0f63d6603f867f729f85d"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1003463670"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "2985138R"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "6790250"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf00286015", 
      "https://app.dimensions.ai/details/publication/pub.1003463670"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T08:52", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000374_0000000374/records_119746_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF00286015"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00286015'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00286015'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00286015'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00286015'


 

This table displays all metadata directly associated to this object as RDF triples.

246 TRIPLES      21 PREDICATES      64 URIs      34 LITERALS      22 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf00286015 schema:about N5ec78d68692d4f4593e06d5b721d943d
2 N601586e0b255470c8638316493493c11
3 N64c6e483bfdd4a75a9ad6541e73366c1
4 N743b6b33cf32496d8536fd9d5aeee6ec
5 N98be27b3fc414ccba299dbc57a9394ad
6 Na2a5f73e361a4445bfb70fe1c25e2b2e
7 Nb2cbb297aa43472282cc4fec0ba9db1b
8 Nc6f6a3c1708f43edb78f3fd397832caf
9 Ndbfae577d5a242c89bb01006e7417b6c
10 Ndd679f46a07a40b4aa5225e8af6651ee
11 Ne3d7f3e958c04c7ca06f001a526c3c8a
12 Nf598fdb7c3094bfc9d3dfd735142bd1e
13 Nf9484a66fbfa4ccfb41f1cb7b617688a
14 anzsrc-for:06
15 anzsrc-for:0604
16 schema:author N1b6276d07c0d45049c260ab1f0edcfd9
17 schema:citation sg:pub.10.1007/978-3-540-37164-9_5
18 sg:pub.10.1007/bf00268674
19 sg:pub.10.1007/bf00269084
20 sg:pub.10.1007/bf00292637
21 sg:pub.10.1007/bf00308501
22 sg:pub.10.1007/bf00332339
23 sg:pub.10.1007/bf00484734
24 sg:pub.10.1038/2141159b0
25 sg:pub.10.1038/287795a0
26 sg:pub.10.1111/j.1601-5223.1979.tb01635.x
27 https://app.dimensions.ai/details/publication/pub.1081470708
28 https://app.dimensions.ai/details/publication/pub.1081557428
29 https://app.dimensions.ai/details/publication/pub.1082728636
30 https://app.dimensions.ai/details/publication/pub.1082728647
31 https://doi.org/10.1002/dvg.1020020302
32 https://doi.org/10.1016/0012-1606(80)90412-1
33 https://doi.org/10.1016/0305-0491(72)90241-6
34 https://doi.org/10.1016/b978-0-12-068350-5.50023-5
35 https://doi.org/10.1016/s0091-679x(08)60727-x
36 https://doi.org/10.1073/pnas.77.7.4175
37 https://doi.org/10.1093/oxfordjournals.jhered.a105104
38 https://doi.org/10.1128/mcb.1.6.475
39 schema:datePublished 1981-06
40 schema:datePublishedReg 1981-06-01
41 schema:description Of 204 mutations located in the 8-12 band Df(2L)130 region, 37B9-C1,2;37D1-2, 199 have been assigned to twelve lethal genes and one visible gene (hook). The 13 genes are not evenly distributed. Twelve, (possibly all thirteen) are in the seven band region 37B10-C4 giving a gene-to-band ratio of almost two. Only one gene, 1(2)37Cf, may be in the four band region 37C5-7, and none are localized in band 37D1. In situ hybridization places the dopa decarboxylase structural gene, Ddc, in or very close to band 37C1,2 (Hirsh and Davidson, 1981). The chi methyl dopa hypersensitive gene, 1(2) and, is 0.002 map units distal to Ddc. Df(2L)VA17, 37C1,2; 37F5-38A1 may actually break in the 37C1,2 singlet. It places six genes, hook, 1(2) and, and four lethal genes, in a maximum of five bands, 37B10, 11, 12, 13 and perhaps part of the 37C1,2 singlet and localizes six genes, Ddc plus five lethal genes, in a maximum of three bands; probably part of the 37C1,2 singlet plus bands, C3, and C4. Wild type activity of five of twelve lethal genes is necessary for female fertility. --Band 37C5 puffs at the time of pupariation; Puff Stages 8-10. Twelve of eighteen alleles of 1(2)37Cf have been examined as heterozygotes over CyO and none affect the appearance of a homozygous 37C5 puff. --Of the 204 mutations considered here only one Ddcpl, affects the function of more than one gene. It eliminates Ddc+ and 1(2)37Ca+ function and at 30 degrees C reduces 1(2)37Ce+ function. It is not a deficiency but could be a polar mutant.
42 schema:genre research_article
43 schema:inLanguage en
44 schema:isAccessibleForFree false
45 schema:isPartOf N0d3d66f741a94a688edd9b4f780784fd
46 Nceed1b4ba6444a0eb1f1290bd22a1055
47 sg:journal.1312277
48 schema:name The genetics of dopa decarboxylase in Drosophila melanogaster
49 schema:pagination 45-58
50 schema:productId N165d1c5f4dec4ab4aad381d627fc08e7
51 N2f3855bc646b4eb1a1464f677864fc27
52 N4d0be9ab95344351889e595adda6b220
53 Ne75a53d804cf4d6391b7e22ac9f43860
54 Nf6c245132c0c4bbebed800757d6a8e1a
55 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003463670
56 https://doi.org/10.1007/bf00286015
57 schema:sdDatePublished 2019-04-15T08:52
58 schema:sdLicense https://scigraph.springernature.com/explorer/license/
59 schema:sdPublisher Ndd3ff60035e648cb88a5ebf13e11d007
60 schema:url http://link.springer.com/10.1007/BF00286015
61 sgo:license sg:explorer/license/
62 sgo:sdDataset articles
63 rdf:type schema:ScholarlyArticle
64 N086c73fa120d41a796dfdac9e6907076 rdf:first sg:person.0601520667.38
65 rdf:rest rdf:nil
66 N0d3d66f741a94a688edd9b4f780784fd schema:volumeNumber 83
67 rdf:type schema:PublicationVolume
68 N0f09401fc2ca4d2ea52c5dec73508428 rdf:first sg:person.01142563167.91
69 rdf:rest Nec46d32ea93c4107a943ea7b0c5a4394
70 N165d1c5f4dec4ab4aad381d627fc08e7 schema:name pubmed_id
71 schema:value 6790250
72 rdf:type schema:PropertyValue
73 N1b6276d07c0d45049c260ab1f0edcfd9 rdf:first sg:person.063415164.38
74 rdf:rest N8758a2eada154413b615f2ca4a4ee2e4
75 N21205f69c42f4bf6afdbfe5211f90384 rdf:first N440d5f1e7b524cd6a02e15538c573c60
76 rdf:rest N086c73fa120d41a796dfdac9e6907076
77 N2f3855bc646b4eb1a1464f677864fc27 schema:name doi
78 schema:value 10.1007/bf00286015
79 rdf:type schema:PropertyValue
80 N440d5f1e7b524cd6a02e15538c573c60 schema:affiliation https://www.grid.ac/institutes/grid.27755.32
81 schema:familyName Tomsett
82 schema:givenName Anne D.
83 rdf:type schema:Person
84 N4d0be9ab95344351889e595adda6b220 schema:name readcube_id
85 schema:value 107ff559411d9f8c07ad33f8688a62fe3268ca66b1f0f63d6603f867f729f85d
86 rdf:type schema:PropertyValue
87 N5ec78d68692d4f4593e06d5b721d943d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Ethyl Methanesulfonate
89 rdf:type schema:DefinedTerm
90 N601586e0b255470c8638316493493c11 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Female
92 rdf:type schema:DefinedTerm
93 N64c6e483bfdd4a75a9ad6541e73366c1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Dopa Decarboxylase
95 rdf:type schema:DefinedTerm
96 N743b6b33cf32496d8536fd9d5aeee6ec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Genes, Lethal
98 rdf:type schema:DefinedTerm
99 N8758a2eada154413b615f2ca4a4ee2e4 rdf:first sg:person.075355426.22
100 rdf:rest Ne34e6f7ef7db45c69eedd5e354bd87c1
101 N98be27b3fc414ccba299dbc57a9394ad schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Chromosome Mapping
103 rdf:type schema:DefinedTerm
104 Na2a5f73e361a4445bfb70fe1c25e2b2e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Genes
106 rdf:type schema:DefinedTerm
107 Nb2cbb297aa43472282cc4fec0ba9db1b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name Aromatic-L-Amino-Acid Decarboxylases
109 rdf:type schema:DefinedTerm
110 Nc6f6a3c1708f43edb78f3fd397832caf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name Chromosomes
112 rdf:type schema:DefinedTerm
113 Ncacf5856d4664a178dca5ea80f426da1 rdf:first sg:person.0625443547.21
114 rdf:rest N21205f69c42f4bf6afdbfe5211f90384
115 Nceed1b4ba6444a0eb1f1290bd22a1055 schema:issueNumber 1
116 rdf:type schema:PublicationIssue
117 Ndbfae577d5a242c89bb01006e7417b6c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
118 schema:name Mutagens
119 rdf:type schema:DefinedTerm
120 Ndd3ff60035e648cb88a5ebf13e11d007 schema:name Springer Nature - SN SciGraph project
121 rdf:type schema:Organization
122 Ndd679f46a07a40b4aa5225e8af6651ee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Drosophila melanogaster
124 rdf:type schema:DefinedTerm
125 Ne34e6f7ef7db45c69eedd5e354bd87c1 rdf:first sg:person.010150652252.29
126 rdf:rest N0f09401fc2ca4d2ea52c5dec73508428
127 Ne3d7f3e958c04c7ca06f001a526c3c8a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Mutation
129 rdf:type schema:DefinedTerm
130 Ne75a53d804cf4d6391b7e22ac9f43860 schema:name dimensions_id
131 schema:value pub.1003463670
132 rdf:type schema:PropertyValue
133 Nec46d32ea93c4107a943ea7b0c5a4394 rdf:first sg:person.014541275651.71
134 rdf:rest Ncacf5856d4664a178dca5ea80f426da1
135 Nf598fdb7c3094bfc9d3dfd735142bd1e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
136 schema:name Infertility, Female
137 rdf:type schema:DefinedTerm
138 Nf6c245132c0c4bbebed800757d6a8e1a schema:name nlm_unique_id
139 schema:value 2985138R
140 rdf:type schema:PropertyValue
141 Nf9484a66fbfa4ccfb41f1cb7b617688a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Animals
143 rdf:type schema:DefinedTerm
144 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
145 schema:name Biological Sciences
146 rdf:type schema:DefinedTerm
147 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
148 schema:name Genetics
149 rdf:type schema:DefinedTerm
150 sg:grant.2508739 http://pending.schema.org/fundedItem sg:pub.10.1007/bf00286015
151 rdf:type schema:MonetaryGrant
152 sg:journal.1312277 schema:issn 0009-5915
153 1432-0886
154 schema:name Chromosoma
155 rdf:type schema:Periodical
156 sg:person.010150652252.29 schema:affiliation https://www.grid.ac/institutes/grid.27755.32
157 schema:familyName Marsh
158 schema:givenName J. Lawrence
159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010150652252.29
160 rdf:type schema:Person
161 sg:person.01142563167.91 schema:affiliation https://www.grid.ac/institutes/grid.27755.32
162 schema:familyName Bishop
163 schema:givenName Clifton P.
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142563167.91
165 rdf:type schema:Person
166 sg:person.014541275651.71 schema:affiliation https://www.grid.ac/institutes/grid.27755.32
167 schema:familyName Steward
168 schema:givenName Ruth
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014541275651.71
170 rdf:type schema:Person
171 sg:person.0601520667.38 schema:affiliation https://www.grid.ac/institutes/grid.27755.32
172 schema:familyName Wright
173 schema:givenName Eileen Y.
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0601520667.38
175 rdf:type schema:Person
176 sg:person.0625443547.21 schema:affiliation https://www.grid.ac/institutes/grid.27755.32
177 schema:familyName Black
178 schema:givenName Bruce C.
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625443547.21
180 rdf:type schema:Person
181 sg:person.063415164.38 schema:affiliation https://www.grid.ac/institutes/grid.27755.32
182 schema:familyName Wright
183 schema:givenName Theodore R. F.
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.063415164.38
185 rdf:type schema:Person
186 sg:person.075355426.22 schema:affiliation https://www.grid.ac/institutes/grid.419580.1
187 schema:familyName Beermann
188 schema:givenName Wolfgang
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.075355426.22
190 rdf:type schema:Person
191 sg:pub.10.1007/978-3-540-37164-9_5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026333918
192 https://doi.org/10.1007/978-3-540-37164-9_5
193 rdf:type schema:CreativeWork
194 sg:pub.10.1007/bf00268674 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017196477
195 https://doi.org/10.1007/bf00268674
196 rdf:type schema:CreativeWork
197 sg:pub.10.1007/bf00269084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005381898
198 https://doi.org/10.1007/bf00269084
199 rdf:type schema:CreativeWork
200 sg:pub.10.1007/bf00292637 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050513478
201 https://doi.org/10.1007/bf00292637
202 rdf:type schema:CreativeWork
203 sg:pub.10.1007/bf00308501 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016404862
204 https://doi.org/10.1007/bf00308501
205 rdf:type schema:CreativeWork
206 sg:pub.10.1007/bf00332339 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036627089
207 https://doi.org/10.1007/bf00332339
208 rdf:type schema:CreativeWork
209 sg:pub.10.1007/bf00484734 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045527525
210 https://doi.org/10.1007/bf00484734
211 rdf:type schema:CreativeWork
212 sg:pub.10.1038/2141159b0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041317461
213 https://doi.org/10.1038/2141159b0
214 rdf:type schema:CreativeWork
215 sg:pub.10.1038/287795a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017279186
216 https://doi.org/10.1038/287795a0
217 rdf:type schema:CreativeWork
218 sg:pub.10.1111/j.1601-5223.1979.tb01635.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1018731393
219 https://doi.org/10.1111/j.1601-5223.1979.tb01635.x
220 rdf:type schema:CreativeWork
221 https://app.dimensions.ai/details/publication/pub.1081470708 schema:CreativeWork
222 https://app.dimensions.ai/details/publication/pub.1081557428 schema:CreativeWork
223 https://app.dimensions.ai/details/publication/pub.1082728636 schema:CreativeWork
224 https://app.dimensions.ai/details/publication/pub.1082728647 schema:CreativeWork
225 https://doi.org/10.1002/dvg.1020020302 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027147433
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1016/0012-1606(80)90412-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047941710
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1016/0305-0491(72)90241-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020597364
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1016/b978-0-12-068350-5.50023-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041976776
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1016/s0091-679x(08)60727-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1008933776
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1073/pnas.77.7.4175 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006530737
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1093/oxfordjournals.jhered.a105104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083483929
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1128/mcb.1.6.475 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015124687
240 rdf:type schema:CreativeWork
241 https://www.grid.ac/institutes/grid.27755.32 schema:alternateName University of Virginia
242 schema:name Department of Biology, University of Virginia, 22903, Charlottesville, VA, USA
243 rdf:type schema:Organization
244 https://www.grid.ac/institutes/grid.419580.1 schema:alternateName Max Planck Institute for Biology
245 schema:name Max Planck Institut für Biologie, Tübingen, Federal Republic of Germany
246 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...