Zum Problem der in vitro-Sensibilitätstestung von Tumoren gegen Cyclophosphamid. 3H-Uridineinbau in Ribonucleinsäure menschlicher Tumorzellen nach Inkubation mit 4-Hydro-peroxy-Cyclophosphamid View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1976-01

AUTHORS

G. Bastert, G. Voelcker, G. Peter, H. Schmidt-Matthiesen, H. J. Hohorst

ABSTRACT

The utility of 4-hydro-peroxy-cyclophosphamide for testing the selectivity of human tumours cells against cyclophosphamide in vitro was studied. 4-hydro-peroxy-cyclophosphamide in aqueous solution spontaneously decomposes to 4-hydroxy-cyclophosphamide, the primary product of metabolic activation of cyclophosphamide thus representing a new form of "activated" cyclophosphamide. From 31 human tumours including 21 mammarian-, 4 ovarial-, 2 uterine-carcinomas, 2 seminomas, 1 hypernephroma and 1 rectum-carcinoma cell suspensions were made and the effect on the 3H-Uridine- and the 3H-Thymidine-incorporation into the nucleic acids after short time incubation with the effect of 4-hydro-peroxy-cyclophosphamide and 4-hydroxy-cyclophosphamide. 7 malignomas showed high sensitivity both against 4-hydro-peroxy-cyclophosphamide and against 4-hydroxy-cyclophosphamide. No additional inhibitory effect of the peroxyde function besides of that of the alkylating moiety of the molecule was found. Accordingly 4-hydro-peroxy-cyclophosphamide because of its better availibility and stability may be used as "activated" cyclophosphamide in screening tests for cyclophosphamide-sensivity of human tumours in vitro. More... »

PAGES

299-307

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00284088

DOI

http://dx.doi.org/10.1007/bf00284088

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013857956

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/131429


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cyclophosphamide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA, Neoplasm", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Evaluation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "In Vitro Techniques", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Peroxides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA, Neoplasm", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Goethe University Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.7839.5", 
          "name": [
            "Abteilung f\u00fcr Gyn\u00e4kologie und Onkologie des Zentrums der Frauenheilkunde und Geburtshilfe des Klinikums der Johann Wolfgang Goethe-Universit\u00e4t, Frankfurt am Main", 
            "Abteilung f\u00fcr Zellchemie des Gustav Emden-Zentrums der Biologischen Chemie der Johann Wolfgang Goethe-Universit\u00e4t, Frankfurt am Main"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bastert", 
        "givenName": "G.", 
        "id": "sg:person.0622753366.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622753366.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Goethe University Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.7839.5", 
          "name": [
            "Abteilung f\u00fcr Gyn\u00e4kologie und Onkologie des Zentrums der Frauenheilkunde und Geburtshilfe des Klinikums der Johann Wolfgang Goethe-Universit\u00e4t, Frankfurt am Main", 
            "Abteilung f\u00fcr Zellchemie des Gustav Emden-Zentrums der Biologischen Chemie der Johann Wolfgang Goethe-Universit\u00e4t, Frankfurt am Main"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Voelcker", 
        "givenName": "G.", 
        "id": "sg:person.072236252.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.072236252.36"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Goethe University Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.7839.5", 
          "name": [
            "Abteilung f\u00fcr Gyn\u00e4kologie und Onkologie des Zentrums der Frauenheilkunde und Geburtshilfe des Klinikums der Johann Wolfgang Goethe-Universit\u00e4t, Frankfurt am Main", 
            "Abteilung f\u00fcr Zellchemie des Gustav Emden-Zentrums der Biologischen Chemie der Johann Wolfgang Goethe-Universit\u00e4t, Frankfurt am Main"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Peter", 
        "givenName": "G.", 
        "id": "sg:person.076077352.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.076077352.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Goethe University Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.7839.5", 
          "name": [
            "Abteilung f\u00fcr Gyn\u00e4kologie und Onkologie des Zentrums der Frauenheilkunde und Geburtshilfe des Klinikums der Johann Wolfgang Goethe-Universit\u00e4t, Frankfurt am Main", 
            "Abteilung f\u00fcr Zellchemie des Gustav Emden-Zentrums der Biologischen Chemie der Johann Wolfgang Goethe-Universit\u00e4t, Frankfurt am Main"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schmidt-Matthiesen", 
        "givenName": "H.", 
        "id": "sg:person.072660461.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.072660461.04"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Goethe University Frankfurt", 
          "id": "https://www.grid.ac/institutes/grid.7839.5", 
          "name": [
            "Abteilung f\u00fcr Gyn\u00e4kologie und Onkologie des Zentrums der Frauenheilkunde und Geburtshilfe des Klinikums der Johann Wolfgang Goethe-Universit\u00e4t, Frankfurt am Main", 
            "Abteilung f\u00fcr Zellchemie des Gustav Emden-Zentrums der Biologischen Chemie der Johann Wolfgang Goethe-Universit\u00e4t, Frankfurt am Main"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hohorst", 
        "givenName": "H. J.", 
        "id": "sg:person.053543626.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.053543626.71"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/bf01191058", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000135012", 
          "https://doi.org/10.1007/bf01191058"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01191058", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000135012", 
          "https://doi.org/10.1007/bf01191058"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01191058", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000135012", 
          "https://doi.org/10.1007/bf01191058"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00305687", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004147226", 
          "https://doi.org/10.1007/bf00305687"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00305687", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004147226", 
          "https://doi.org/10.1007/bf00305687"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(197106)27:6<1512::aid-cncr2820270636>3.0.co;2-q", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004545840"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00525879", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027259241", 
          "https://doi.org/10.1007/bf00525879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00525879", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027259241", 
          "https://doi.org/10.1007/bf00525879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(1967)20:5<900::aid-cncr2820200552>3.0.co;2-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029444155"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00524766", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031685493", 
          "https://doi.org/10.1007/bf00524766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00524766", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031685493", 
          "https://doi.org/10.1007/bf00524766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/bchm2.1961.325.1.65", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051036486"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00602527", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053584461", 
          "https://doi.org/10.1007/bf00602527"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00602527", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053584461", 
          "https://doi.org/10.1007/bf00602527"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00602527", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053584461", 
          "https://doi.org/10.1007/bf00602527"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0028-1106497", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057122237"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0028-1107708", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057123338"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-0028-1113219", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057128733"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074772204", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080377434", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080534722", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080603362", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080696161", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080814339", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1976-01", 
    "datePublishedReg": "1976-01-01", 
    "description": "The utility of 4-hydro-peroxy-cyclophosphamide for testing the selectivity of human tumours cells against cyclophosphamide in vitro was studied. 4-hydro-peroxy-cyclophosphamide in aqueous solution spontaneously decomposes to 4-hydroxy-cyclophosphamide, the primary product of metabolic activation of cyclophosphamide thus representing a new form of \"activated\" cyclophosphamide. From 31 human tumours including 21 mammarian-, 4 ovarial-, 2 uterine-carcinomas, 2 seminomas, 1 hypernephroma and 1 rectum-carcinoma cell suspensions were made and the effect on the 3H-Uridine- and the 3H-Thymidine-incorporation into the nucleic acids after short time incubation with the effect of 4-hydro-peroxy-cyclophosphamide and 4-hydroxy-cyclophosphamide. 7 malignomas showed high sensitivity both against 4-hydro-peroxy-cyclophosphamide and against 4-hydroxy-cyclophosphamide. No additional inhibitory effect of the peroxyde function besides of that of the alkylating moiety of the molecule was found. Accordingly 4-hydro-peroxy-cyclophosphamide because of its better availibility and stability may be used as \"activated\" cyclophosphamide in screening tests for cyclophosphamide-sensivity of human tumours in vitro.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf00284088", 
    "inLanguage": [
      "de"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1319950", 
        "issn": [
          "0084-5353"
        ], 
        "name": "Zeitschrift f\u00fcr Krebsforschung und Klinische Onkologie", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "85"
      }
    ], 
    "name": "Zum Problem der in vitro-Sensibilit\u00e4tstestung von Tumoren gegen Cyclophosphamid. 3H-Uridineinbau in Ribonucleins\u00e4ure menschlicher Tumorzellen nach Inkubation mit 4-Hydro-peroxy-Cyclophosphamid", 
    "pagination": "299-307", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf00284088"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "420421a44898a878fb567723e838f09aba8be4d4d2cdcec408589f539defd77a"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1013857956"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "1276653"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "131429"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf00284088", 
      "https://app.dimensions.ai/details/publication/pub.1013857956"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T08:51", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000374_0000000374/records_119741_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF00284088"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00284088'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00284088'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00284088'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00284088'


 

This table displays all metadata directly associated to this object as RDF triples.

195 TRIPLES      21 PREDICATES      58 URIs      33 LITERALS      21 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf00284088 schema:about N20cd2dcbbfbb4ed788960bb797e3a297
2 N333851e18a0347b796d84eb057445040
3 N5ad7452d791a4f93bf3bfbdcc316531a
4 N68240f43bada4dd4852ae6d15d2c61a1
5 N7411133adcd948fb8c46bfffe70dafcc
6 N98d7415f3b8c45ce906a25c7cb3724fd
7 N9b14d3d84b3d4e8abc88b3c20a390db1
8 Ncc60e9caaae14db9ad21ab27c1938ed2
9 Ncd58fd420a8149eda4f3ce688e503a5e
10 Nd6ba5193a4ee4120880bef03ba70d3cc
11 Neadc87b7b3c248c2af02ce6fbc4acbe2
12 Nf3c0d69289cd499680459c4d906af498
13 anzsrc-for:06
14 anzsrc-for:0601
15 schema:author Ndc9fc734f6994f6d9edec54c1eb321cf
16 schema:citation sg:pub.10.1007/bf00305687
17 sg:pub.10.1007/bf00524766
18 sg:pub.10.1007/bf00525879
19 sg:pub.10.1007/bf00602527
20 sg:pub.10.1007/bf01191058
21 https://app.dimensions.ai/details/publication/pub.1074772204
22 https://app.dimensions.ai/details/publication/pub.1080377434
23 https://app.dimensions.ai/details/publication/pub.1080534722
24 https://app.dimensions.ai/details/publication/pub.1080603362
25 https://app.dimensions.ai/details/publication/pub.1080696161
26 https://app.dimensions.ai/details/publication/pub.1080814339
27 https://doi.org/10.1002/1097-0142(1967)20:5<900::aid-cncr2820200552>3.0.co;2-y
28 https://doi.org/10.1002/1097-0142(197106)27:6<1512::aid-cncr2820270636>3.0.co;2-q
29 https://doi.org/10.1055/s-0028-1106497
30 https://doi.org/10.1055/s-0028-1107708
31 https://doi.org/10.1055/s-0028-1113219
32 https://doi.org/10.1515/bchm2.1961.325.1.65
33 schema:datePublished 1976-01
34 schema:datePublishedReg 1976-01-01
35 schema:description The utility of 4-hydro-peroxy-cyclophosphamide for testing the selectivity of human tumours cells against cyclophosphamide in vitro was studied. 4-hydro-peroxy-cyclophosphamide in aqueous solution spontaneously decomposes to 4-hydroxy-cyclophosphamide, the primary product of metabolic activation of cyclophosphamide thus representing a new form of "activated" cyclophosphamide. From 31 human tumours including 21 mammarian-, 4 ovarial-, 2 uterine-carcinomas, 2 seminomas, 1 hypernephroma and 1 rectum-carcinoma cell suspensions were made and the effect on the 3H-Uridine- and the 3H-Thymidine-incorporation into the nucleic acids after short time incubation with the effect of 4-hydro-peroxy-cyclophosphamide and 4-hydroxy-cyclophosphamide. 7 malignomas showed high sensitivity both against 4-hydro-peroxy-cyclophosphamide and against 4-hydroxy-cyclophosphamide. No additional inhibitory effect of the peroxyde function besides of that of the alkylating moiety of the molecule was found. Accordingly 4-hydro-peroxy-cyclophosphamide because of its better availibility and stability may be used as "activated" cyclophosphamide in screening tests for cyclophosphamide-sensivity of human tumours in vitro.
36 schema:genre research_article
37 schema:inLanguage de
38 schema:isAccessibleForFree false
39 schema:isPartOf N1121fa73009c4e1c8655839a5fe1293f
40 Ncbd3ddee1d304ccbb5260a407d8fa366
41 sg:journal.1319950
42 schema:name Zum Problem der in vitro-Sensibilitätstestung von Tumoren gegen Cyclophosphamid. 3H-Uridineinbau in Ribonucleinsäure menschlicher Tumorzellen nach Inkubation mit 4-Hydro-peroxy-Cyclophosphamid
43 schema:pagination 299-307
44 schema:productId N4529aab81012496d995a61d290a06d6c
45 N48d25ceb932346e1b0f7fa64baa35a81
46 N7160bd45b1414d3d953523c6f7277f59
47 N8a2bd5c76b874f1da417cc4c43ac47d3
48 Nc89fc4e06cac4dd4a4d8acd17e033c94
49 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013857956
50 https://doi.org/10.1007/bf00284088
51 schema:sdDatePublished 2019-04-15T08:51
52 schema:sdLicense https://scigraph.springernature.com/explorer/license/
53 schema:sdPublisher N230530f4e8ca4304b2b1fda102a3647d
54 schema:url http://link.springer.com/10.1007/BF00284088
55 sgo:license sg:explorer/license/
56 sgo:sdDataset articles
57 rdf:type schema:ScholarlyArticle
58 N1121fa73009c4e1c8655839a5fe1293f schema:issueNumber 3
59 rdf:type schema:PublicationIssue
60 N20cd2dcbbfbb4ed788960bb797e3a297 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
61 schema:name Female
62 rdf:type schema:DefinedTerm
63 N230530f4e8ca4304b2b1fda102a3647d schema:name Springer Nature - SN SciGraph project
64 rdf:type schema:Organization
65 N333851e18a0347b796d84eb057445040 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
66 schema:name In Vitro Techniques
67 rdf:type schema:DefinedTerm
68 N4529aab81012496d995a61d290a06d6c schema:name readcube_id
69 schema:value 420421a44898a878fb567723e838f09aba8be4d4d2cdcec408589f539defd77a
70 rdf:type schema:PropertyValue
71 N48d25ceb932346e1b0f7fa64baa35a81 schema:name doi
72 schema:value 10.1007/bf00284088
73 rdf:type schema:PropertyValue
74 N51378d12d1b143338ec2d9c676966020 rdf:first sg:person.072236252.36
75 rdf:rest N87c76797a67c4031a7b60368623a133e
76 N5ad7452d791a4f93bf3bfbdcc316531a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
77 schema:name Neoplasms
78 rdf:type schema:DefinedTerm
79 N68240f43bada4dd4852ae6d15d2c61a1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Middle Aged
81 rdf:type schema:DefinedTerm
82 N7160bd45b1414d3d953523c6f7277f59 schema:name nlm_unique_id
83 schema:value 1276653
84 rdf:type schema:PropertyValue
85 N7411133adcd948fb8c46bfffe70dafcc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name RNA, Neoplasm
87 rdf:type schema:DefinedTerm
88 N7b6195d7db9a45619066c5fffccc78ff rdf:first sg:person.053543626.71
89 rdf:rest rdf:nil
90 N87c76797a67c4031a7b60368623a133e rdf:first sg:person.076077352.01
91 rdf:rest N9442198540214099a311dff346c58394
92 N8a2bd5c76b874f1da417cc4c43ac47d3 schema:name pubmed_id
93 schema:value 131429
94 rdf:type schema:PropertyValue
95 N9442198540214099a311dff346c58394 rdf:first sg:person.072660461.04
96 rdf:rest N7b6195d7db9a45619066c5fffccc78ff
97 N98d7415f3b8c45ce906a25c7cb3724fd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Humans
99 rdf:type schema:DefinedTerm
100 N9b14d3d84b3d4e8abc88b3c20a390db1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Drug Evaluation
102 rdf:type schema:DefinedTerm
103 Nc89fc4e06cac4dd4a4d8acd17e033c94 schema:name dimensions_id
104 schema:value pub.1013857956
105 rdf:type schema:PropertyValue
106 Ncbd3ddee1d304ccbb5260a407d8fa366 schema:volumeNumber 85
107 rdf:type schema:PublicationVolume
108 Ncc60e9caaae14db9ad21ab27c1938ed2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Cyclophosphamide
110 rdf:type schema:DefinedTerm
111 Ncd58fd420a8149eda4f3ce688e503a5e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Peroxides
113 rdf:type schema:DefinedTerm
114 Nd6ba5193a4ee4120880bef03ba70d3cc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name DNA, Neoplasm
116 rdf:type schema:DefinedTerm
117 Ndc9fc734f6994f6d9edec54c1eb321cf rdf:first sg:person.0622753366.33
118 rdf:rest N51378d12d1b143338ec2d9c676966020
119 Neadc87b7b3c248c2af02ce6fbc4acbe2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Aged
121 rdf:type schema:DefinedTerm
122 Nf3c0d69289cd499680459c4d906af498 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Adult
124 rdf:type schema:DefinedTerm
125 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
126 schema:name Biological Sciences
127 rdf:type schema:DefinedTerm
128 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
129 schema:name Biochemistry and Cell Biology
130 rdf:type schema:DefinedTerm
131 sg:journal.1319950 schema:issn 0084-5353
132 schema:name Zeitschrift für Krebsforschung und Klinische Onkologie
133 rdf:type schema:Periodical
134 sg:person.053543626.71 schema:affiliation https://www.grid.ac/institutes/grid.7839.5
135 schema:familyName Hohorst
136 schema:givenName H. J.
137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.053543626.71
138 rdf:type schema:Person
139 sg:person.0622753366.33 schema:affiliation https://www.grid.ac/institutes/grid.7839.5
140 schema:familyName Bastert
141 schema:givenName G.
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622753366.33
143 rdf:type schema:Person
144 sg:person.072236252.36 schema:affiliation https://www.grid.ac/institutes/grid.7839.5
145 schema:familyName Voelcker
146 schema:givenName G.
147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.072236252.36
148 rdf:type schema:Person
149 sg:person.072660461.04 schema:affiliation https://www.grid.ac/institutes/grid.7839.5
150 schema:familyName Schmidt-Matthiesen
151 schema:givenName H.
152 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.072660461.04
153 rdf:type schema:Person
154 sg:person.076077352.01 schema:affiliation https://www.grid.ac/institutes/grid.7839.5
155 schema:familyName Peter
156 schema:givenName G.
157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.076077352.01
158 rdf:type schema:Person
159 sg:pub.10.1007/bf00305687 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004147226
160 https://doi.org/10.1007/bf00305687
161 rdf:type schema:CreativeWork
162 sg:pub.10.1007/bf00524766 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031685493
163 https://doi.org/10.1007/bf00524766
164 rdf:type schema:CreativeWork
165 sg:pub.10.1007/bf00525879 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027259241
166 https://doi.org/10.1007/bf00525879
167 rdf:type schema:CreativeWork
168 sg:pub.10.1007/bf00602527 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053584461
169 https://doi.org/10.1007/bf00602527
170 rdf:type schema:CreativeWork
171 sg:pub.10.1007/bf01191058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000135012
172 https://doi.org/10.1007/bf01191058
173 rdf:type schema:CreativeWork
174 https://app.dimensions.ai/details/publication/pub.1074772204 schema:CreativeWork
175 https://app.dimensions.ai/details/publication/pub.1080377434 schema:CreativeWork
176 https://app.dimensions.ai/details/publication/pub.1080534722 schema:CreativeWork
177 https://app.dimensions.ai/details/publication/pub.1080603362 schema:CreativeWork
178 https://app.dimensions.ai/details/publication/pub.1080696161 schema:CreativeWork
179 https://app.dimensions.ai/details/publication/pub.1080814339 schema:CreativeWork
180 https://doi.org/10.1002/1097-0142(1967)20:5<900::aid-cncr2820200552>3.0.co;2-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1029444155
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1002/1097-0142(197106)27:6<1512::aid-cncr2820270636>3.0.co;2-q schema:sameAs https://app.dimensions.ai/details/publication/pub.1004545840
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1055/s-0028-1106497 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057122237
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1055/s-0028-1107708 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057123338
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1055/s-0028-1113219 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057128733
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1515/bchm2.1961.325.1.65 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051036486
191 rdf:type schema:CreativeWork
192 https://www.grid.ac/institutes/grid.7839.5 schema:alternateName Goethe University Frankfurt
193 schema:name Abteilung für Gynäkologie und Onkologie des Zentrums der Frauenheilkunde und Geburtshilfe des Klinikums der Johann Wolfgang Goethe-Universität, Frankfurt am Main
194 Abteilung für Zellchemie des Gustav Emden-Zentrums der Biologischen Chemie der Johann Wolfgang Goethe-Universität, Frankfurt am Main
195 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...