Deletion 14q(q24.3 to q32.1) syndrome: significance of peculiar facial appearance in its diagnosis, and deletion mapping of (α1-antitrypsin) View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1986-10

AUTHORS

Y. Yamamoto, R. Sawa, N. Okamoto, A. Matsui, M. Yanagisawa, S. Ikemoto

ABSTRACT

A 10-month-old Japanese boy who had interstitial deletion of the long arm of chromosome No. 14; 46,XY, del(14)(pter»q24.3::q32.1»qter) is reported. A peculiar facial appearance, including round face, frontal hypertrichosis with thick eyebrows, horizontal narrow palpebral fissures, a short bulbous nose with a flat nasal root, and mild micrognathia, appeared to be common with the two previously reported cases. We stress the significance of this peculiar facial appearance in the diagnosis of 14q-(q24.3 to q32.1) syndrome. The level of α1-antitrypsin in the patient was only about half of that of his parents and controls, and the Pi locus was tentatively assigned to band 14q32.1. More... »

PAGES

190-192

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00282092

DOI

http://dx.doi.org/10.1007/bf00282092

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010436076

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3490426


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