The ras-related ral gene maps to chromosome 7p15-22 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1988-06

AUTHORS

Marie-Françoise Rousseau-Merck, Alain Bernheim, Pierre Chardin, Roger Miglierina, Armand Tavitian, Roland Berger

ABSTRACT

Human cDNAs coding for the new protein ral that shares 50% homology with the ras proteins have been recently isolated. A 600-bp fragment carrying mainly the coding region was used to localize the ral gene by hybridization with sorted chromosomes and in situ hybridization. Direct molecular hybridization on sorted chromosomes using a single laser illumination allowed the assignment of the ral gene to a region of the flow karyotype containing chromosomes 7, 8 and X. With dual laser analysis ral was assigned to the fraction containing chromosome 7. In the 331 human metaphases hybridized with the 3H-labelled insert, the silver grain distribution showed a unique major signal on chromosome 7p15-22. More... »

PAGES

132-136

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00280551

DOI

http://dx.doi.org/10.1007/bf00280551

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1044814045

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3292391


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