Ontology type: schema:ScholarlyArticle
1974-06
AUTHORSA. Czeizel, L. Csósz, Judit Gárdonyi, L. Remenár, P. Ruziscka
ABSTRACTChromosome studies in 12 children suffering from retinoblastoma revealed a significantly elevated frequency of aneuploids, chromatid-type aberrations and stable abnormalities of the chromosome type. A similar increase in the occurrence of chromosome abnormalities was found in cases of retinoblastoma not exposed to therapeutic irradiation. These findings indicate that an increased fragility of the chromosomes must be assumed in patients with retinoblastoma, which may be associated with a general increase in the predisposition to develop tumors. More... »
PAGES159-166
http://scigraph.springernature.com/pub.10.1007/bf00278455
DOIhttp://dx.doi.org/10.1007/bf00278455
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/4843909
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