Correlation of islet cell antibodies and HLA-DR phenotypes with diabetes mellitus in adults View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1984-07

AUTHORS

H. Gleichmann, B. Zörcher, B. Greulich, F. A. Gries, H. R. Henrichs, J. Bertrams, H. Kolb

ABSTRACT

In a cross-sectional study, sera of 81 adult diabetic in-patients were tested for the presence of pancreatic islet cell antibodies (ICA), both IgG and complement-fixing. All patients had been well controlled initially with oral hypoglycaemic agents and therefore had been classified as having Type 2 (non-insulin-dependent) diabetes. However, 14 were subsequently classified as Type 1 (insulin-dependent) because they became insulin-dependent within 2 months of diagnosis. Ten of these patients (71%) were ICA-positive. Sixty-seven patients had been non-insulin-dependent for at least 1 year after diagnosis. Circulating ICA were present in 18 patients and 16 of these (89%) required insulin therapy. Secondary oral hypoglycaemic agent failure developed within a mean period of 3.7 years after diagnosis. In contrast, in the ICA-negative sub-group (n = 49) insulin treatment became necessary in 29 patients. Secondary oral hypoglycaemic agent failure of these patients had developed after a mean period of 8.4 years, which was significantly longer than in the ICA-positive patients (p less than 0.01). Complement-fixing-ICA were detected only in sera with an ICA-IgG titre of at least 8, and its prevalence was similar in the sub-groups tested, i.e., the Type 1 diabetic patients and the patients with secondary oral hypoglycaemic agent failure. With HLA-DR typing, a significant excess of the DR3 antigen and heterozygous DR3/DR4 phenotypes was found in ICA-positive patients with secondary oral hypoglycaemic agent failure and in the Type 1 diabetic patients, which was comparable with the frequencies reported in juvenile-onset Type 1 diabetes. More... »

PAGES

90-92

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00275656

DOI

http://dx.doi.org/10.1007/bf00275656

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1031426260

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6383926


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Clinical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Adult", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antibodies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Autoantibodies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diabetes Mellitus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diabetes Mellitus, Type 1", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diabetes Mellitus, Type 2", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HLA-DR Antigens", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Histocompatibility Antigens Class II", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hypoglycemic Agents", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Islets of Langerhans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phenotype", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Heinrich Heine University D\u00fcsseldorf", 
          "id": "https://www.grid.ac/institutes/grid.411327.2", 
          "name": [
            "Diabetes Research Institute, University of D\u00fcsseldorf, D\u00fcsseldorf, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gleichmann", 
        "givenName": "H.", 
        "id": "sg:person.0111655462.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0111655462.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heinrich Heine University D\u00fcsseldorf", 
          "id": "https://www.grid.ac/institutes/grid.411327.2", 
          "name": [
            "Diabetes Research Institute, University of D\u00fcsseldorf, D\u00fcsseldorf, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Z\u00f6rcher", 
        "givenName": "B.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heinrich Heine University D\u00fcsseldorf", 
          "id": "https://www.grid.ac/institutes/grid.411327.2", 
          "name": [
            "Diabetes Research Institute, University of D\u00fcsseldorf, D\u00fcsseldorf, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Greulich", 
        "givenName": "B.", 
        "id": "sg:person.01315512375.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01315512375.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heinrich Heine University D\u00fcsseldorf", 
          "id": "https://www.grid.ac/institutes/grid.411327.2", 
          "name": [
            "Diabetes Research Institute, University of D\u00fcsseldorf, D\u00fcsseldorf, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gries", 
        "givenName": "F. A.", 
        "id": "sg:person.01320366574.43", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01320366574.43"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Diabetes Centre Quakenbr\u00fcck, Quakenbr\u00fcck, Essen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Henrichs", 
        "givenName": "H. R.", 
        "id": "sg:person.0604366274.42", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604366274.42"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Elisabeth-Hospital, Essen, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bertrams", 
        "givenName": "J.", 
        "id": "sg:person.01147653463.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01147653463.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Heinrich Heine University D\u00fcsseldorf", 
          "id": "https://www.grid.ac/institutes/grid.411327.2", 
          "name": [
            "Diabetes Research Institute, University of D\u00fcsseldorf, D\u00fcsseldorf, Germany"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kolb", 
        "givenName": "H.", 
        "id": "sg:person.01332010455.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332010455.05"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0140-6736(83)91481-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001348749"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(83)91481-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001348749"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(76)92033-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003477826"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(76)92033-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003477826"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00275267", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011036776", 
          "https://doi.org/10.1007/bf00275267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00275267", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011036776", 
          "https://doi.org/10.1007/bf00275267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00275267", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011036776", 
          "https://doi.org/10.1007/bf00275267"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00282516", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011393555", 
          "https://doi.org/10.1007/bf00282516"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00282516", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011393555", 
          "https://doi.org/10.1007/bf00282516"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00252258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022772619", 
          "https://doi.org/10.1007/bf00252258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00252258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022772619", 
          "https://doi.org/10.1007/bf00252258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00252258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022772619", 
          "https://doi.org/10.1007/bf00252258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(74)90140-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033242317"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00282704", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041591620", 
          "https://doi.org/10.1007/bf00282704"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00282704", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041591620", 
          "https://doi.org/10.1007/bf00282704"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(80)92825-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045820507"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diab.32.8.743", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070734411"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083258223", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1984-07", 
    "datePublishedReg": "1984-07-01", 
    "description": "In a cross-sectional study, sera of 81 adult diabetic in-patients were tested for the presence of pancreatic islet cell antibodies (ICA), both IgG and complement-fixing. All patients had been well controlled initially with oral hypoglycaemic agents and therefore had been classified as having Type 2 (non-insulin-dependent) diabetes. However, 14 were subsequently classified as Type 1 (insulin-dependent) because they became insulin-dependent within 2 months of diagnosis. Ten of these patients (71%) were ICA-positive. Sixty-seven patients had been non-insulin-dependent for at least 1 year after diagnosis. Circulating ICA were present in 18 patients and 16 of these (89%) required insulin therapy. Secondary oral hypoglycaemic agent failure developed within a mean period of 3.7 years after diagnosis. In contrast, in the ICA-negative sub-group (n = 49) insulin treatment became necessary in 29 patients. Secondary oral hypoglycaemic agent failure of these patients had developed after a mean period of 8.4 years, which was significantly longer than in the ICA-positive patients (p less than 0.01). Complement-fixing-ICA were detected only in sera with an ICA-IgG titre of at least 8, and its prevalence was similar in the sub-groups tested, i.e., the Type 1 diabetic patients and the patients with secondary oral hypoglycaemic agent failure. With HLA-DR typing, a significant excess of the DR3 antigen and heterozygous DR3/DR4 phenotypes was found in ICA-positive patients with secondary oral hypoglycaemic agent failure and in the Type 1 diabetic patients, which was comparable with the frequencies reported in juvenile-onset Type 1 diabetes.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf00275656", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isPartOf": [
      {
        "id": "sg:journal.1001482", 
        "issn": [
          "0012-186X", 
          "1432-0428"
        ], 
        "name": "Diabetologia", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "Suppl 1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "27"
      }
    ], 
    "name": "Correlation of islet cell antibodies and HLA-DR phenotypes with diabetes mellitus in adults", 
    "pagination": "90-92", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "95b54d81baf25cb529f4e11a72f5e75604c27ea52f87ad9d3998f5c9043ea719"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "6383926"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0006777"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf00275656"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1031426260"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf00275656", 
      "https://app.dimensions.ai/details/publication/pub.1031426260"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:50", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000371_0000000371/records_130797_00000002.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://link.springer.com/10.1007%2FBF00275656"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00275656'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00275656'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00275656'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00275656'


 

This table displays all metadata directly associated to this object as RDF triples.

203 TRIPLES      21 PREDICATES      53 URIs      35 LITERALS      23 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf00275656 schema:about N1fcac22510be4b1ca8c8b8fdc11b3269
2 N3fcd3c5178d9482c952b6864c75ca4c5
3 N598d8ccc7b1a462b9d044c50cd42c906
4 N5f059d0757af4919a7d00d2d75a1495d
5 N7fdabff7cf6345c7b41f2ce580693d60
6 N841ed2cc328442fdbdbe33af49b3accc
7 N9167b147ec644c98b7405769e3d9048f
8 Na45cab82678a4a2da5c3b3325036c591
9 Nbc1e9738fabe44d9ba6143e63a1a8791
10 Nc20c1ade82cb4d82978d038c6b6da579
11 Nc5bced8db7154377a50cd0289c4a27b8
12 Nd481d4c1213f4c988a88083912a53128
13 Nd8505910235744fe861314467bb542bf
14 Ne86c0fc538da41f6853c0264f463a55c
15 anzsrc-for:11
16 anzsrc-for:1103
17 schema:author Nf1e446842c5e402ba60903647832a2d2
18 schema:citation sg:pub.10.1007/bf00252258
19 sg:pub.10.1007/bf00275267
20 sg:pub.10.1007/bf00282516
21 sg:pub.10.1007/bf00282704
22 https://app.dimensions.ai/details/publication/pub.1083258223
23 https://doi.org/10.1016/s0140-6736(74)90140-8
24 https://doi.org/10.1016/s0140-6736(76)92033-x
25 https://doi.org/10.1016/s0140-6736(80)92825-1
26 https://doi.org/10.1016/s0140-6736(83)91481-2
27 https://doi.org/10.2337/diab.32.8.743
28 schema:datePublished 1984-07
29 schema:datePublishedReg 1984-07-01
30 schema:description In a cross-sectional study, sera of 81 adult diabetic in-patients were tested for the presence of pancreatic islet cell antibodies (ICA), both IgG and complement-fixing. All patients had been well controlled initially with oral hypoglycaemic agents and therefore had been classified as having Type 2 (non-insulin-dependent) diabetes. However, 14 were subsequently classified as Type 1 (insulin-dependent) because they became insulin-dependent within 2 months of diagnosis. Ten of these patients (71%) were ICA-positive. Sixty-seven patients had been non-insulin-dependent for at least 1 year after diagnosis. Circulating ICA were present in 18 patients and 16 of these (89%) required insulin therapy. Secondary oral hypoglycaemic agent failure developed within a mean period of 3.7 years after diagnosis. In contrast, in the ICA-negative sub-group (n = 49) insulin treatment became necessary in 29 patients. Secondary oral hypoglycaemic agent failure of these patients had developed after a mean period of 8.4 years, which was significantly longer than in the ICA-positive patients (p less than 0.01). Complement-fixing-ICA were detected only in sera with an ICA-IgG titre of at least 8, and its prevalence was similar in the sub-groups tested, i.e., the Type 1 diabetic patients and the patients with secondary oral hypoglycaemic agent failure. With HLA-DR typing, a significant excess of the DR3 antigen and heterozygous DR3/DR4 phenotypes was found in ICA-positive patients with secondary oral hypoglycaemic agent failure and in the Type 1 diabetic patients, which was comparable with the frequencies reported in juvenile-onset Type 1 diabetes.
31 schema:genre research_article
32 schema:inLanguage en
33 schema:isAccessibleForFree true
34 schema:isPartOf Nb1ea5e83f0704c78ae9f8745a4c348f4
35 Nd863618e4b074de8b6d1b35f8d74bed1
36 sg:journal.1001482
37 schema:name Correlation of islet cell antibodies and HLA-DR phenotypes with diabetes mellitus in adults
38 schema:pagination 90-92
39 schema:productId N1eb85766f77d4e71816b9a523f5f50a6
40 N787af23415304d2d8caccf18acdbcb3c
41 N95c4de1327634684860f188e24502762
42 N98bdf9eaa70449cdb615178b60b59c74
43 Nbf3750b226814ba699e586f32678eabc
44 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031426260
45 https://doi.org/10.1007/bf00275656
46 schema:sdDatePublished 2019-04-11T13:50
47 schema:sdLicense https://scigraph.springernature.com/explorer/license/
48 schema:sdPublisher N1b9374fa9a0a44a2ad3206794cdab1c9
49 schema:url https://link.springer.com/10.1007%2FBF00275656
50 sgo:license sg:explorer/license/
51 sgo:sdDataset articles
52 rdf:type schema:ScholarlyArticle
53 N0eda1398165741148a82eeae33182cea rdf:first sg:person.01320366574.43
54 rdf:rest N8db045dcfeba49ada9616fdef3cd539f
55 N1b9374fa9a0a44a2ad3206794cdab1c9 schema:name Springer Nature - SN SciGraph project
56 rdf:type schema:Organization
57 N1eb85766f77d4e71816b9a523f5f50a6 schema:name doi
58 schema:value 10.1007/bf00275656
59 rdf:type schema:PropertyValue
60 N1fcac22510be4b1ca8c8b8fdc11b3269 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
61 schema:name Histocompatibility Antigens Class II
62 rdf:type schema:DefinedTerm
63 N20bf4b1a4f274c1b9884ff2b4b17f260 schema:name Elisabeth-Hospital, Essen, Germany
64 rdf:type schema:Organization
65 N3f23a190dfb6412cae290d3aba55e2db rdf:first Na13f6725b3b64731a6b2fbee303e4955
66 rdf:rest N9f6b36a225b14083a86705fcb2e1cd29
67 N3fcd3c5178d9482c952b6864c75ca4c5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
68 schema:name Antibodies
69 rdf:type schema:DefinedTerm
70 N598d8ccc7b1a462b9d044c50cd42c906 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
71 schema:name Autoantibodies
72 rdf:type schema:DefinedTerm
73 N5f059d0757af4919a7d00d2d75a1495d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
74 schema:name Aged
75 rdf:type schema:DefinedTerm
76 N787af23415304d2d8caccf18acdbcb3c schema:name pubmed_id
77 schema:value 6383926
78 rdf:type schema:PropertyValue
79 N7fdabff7cf6345c7b41f2ce580693d60 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Diabetes Mellitus
81 rdf:type schema:DefinedTerm
82 N841ed2cc328442fdbdbe33af49b3accc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
83 schema:name Diabetes Mellitus, Type 1
84 rdf:type schema:DefinedTerm
85 N8db045dcfeba49ada9616fdef3cd539f rdf:first sg:person.0604366274.42
86 rdf:rest N922c86df712241a68fb9c91ffb5ee9c1
87 N9167b147ec644c98b7405769e3d9048f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Hypoglycemic Agents
89 rdf:type schema:DefinedTerm
90 N922c86df712241a68fb9c91ffb5ee9c1 rdf:first sg:person.01147653463.13
91 rdf:rest Nea783d7a5be34e6b885b0c8eea322c24
92 N95c4de1327634684860f188e24502762 schema:name dimensions_id
93 schema:value pub.1031426260
94 rdf:type schema:PropertyValue
95 N98bdf9eaa70449cdb615178b60b59c74 schema:name readcube_id
96 schema:value 95b54d81baf25cb529f4e11a72f5e75604c27ea52f87ad9d3998f5c9043ea719
97 rdf:type schema:PropertyValue
98 N9f6b36a225b14083a86705fcb2e1cd29 rdf:first sg:person.01315512375.68
99 rdf:rest N0eda1398165741148a82eeae33182cea
100 Na13f6725b3b64731a6b2fbee303e4955 schema:affiliation https://www.grid.ac/institutes/grid.411327.2
101 schema:familyName Zörcher
102 schema:givenName B.
103 rdf:type schema:Person
104 Na45cab82678a4a2da5c3b3325036c591 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Phenotype
106 rdf:type schema:DefinedTerm
107 Nb1ea5e83f0704c78ae9f8745a4c348f4 schema:issueNumber Suppl 1
108 rdf:type schema:PublicationIssue
109 Nbc1e9738fabe44d9ba6143e63a1a8791 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Middle Aged
111 rdf:type schema:DefinedTerm
112 Nbf3750b226814ba699e586f32678eabc schema:name nlm_unique_id
113 schema:value 0006777
114 rdf:type schema:PropertyValue
115 Nc20c1ade82cb4d82978d038c6b6da579 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Islets of Langerhans
117 rdf:type schema:DefinedTerm
118 Nc5bced8db7154377a50cd0289c4a27b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name HLA-DR Antigens
120 rdf:type schema:DefinedTerm
121 Nd481d4c1213f4c988a88083912a53128 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
122 schema:name Adult
123 rdf:type schema:DefinedTerm
124 Nd8505910235744fe861314467bb542bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Humans
126 rdf:type schema:DefinedTerm
127 Nd863618e4b074de8b6d1b35f8d74bed1 schema:volumeNumber 27
128 rdf:type schema:PublicationVolume
129 Ne86c0fc538da41f6853c0264f463a55c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
130 schema:name Diabetes Mellitus, Type 2
131 rdf:type schema:DefinedTerm
132 Nea783d7a5be34e6b885b0c8eea322c24 rdf:first sg:person.01332010455.05
133 rdf:rest rdf:nil
134 Nef96bb92b207439aadfc74f7edfcfd1e schema:name Diabetes Centre Quakenbrück, Quakenbrück, Essen, Germany
135 rdf:type schema:Organization
136 Nf1e446842c5e402ba60903647832a2d2 rdf:first sg:person.0111655462.17
137 rdf:rest N3f23a190dfb6412cae290d3aba55e2db
138 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
139 schema:name Medical and Health Sciences
140 rdf:type schema:DefinedTerm
141 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
142 schema:name Clinical Sciences
143 rdf:type schema:DefinedTerm
144 sg:journal.1001482 schema:issn 0012-186X
145 1432-0428
146 schema:name Diabetologia
147 rdf:type schema:Periodical
148 sg:person.0111655462.17 schema:affiliation https://www.grid.ac/institutes/grid.411327.2
149 schema:familyName Gleichmann
150 schema:givenName H.
151 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0111655462.17
152 rdf:type schema:Person
153 sg:person.01147653463.13 schema:affiliation N20bf4b1a4f274c1b9884ff2b4b17f260
154 schema:familyName Bertrams
155 schema:givenName J.
156 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01147653463.13
157 rdf:type schema:Person
158 sg:person.01315512375.68 schema:affiliation https://www.grid.ac/institutes/grid.411327.2
159 schema:familyName Greulich
160 schema:givenName B.
161 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01315512375.68
162 rdf:type schema:Person
163 sg:person.01320366574.43 schema:affiliation https://www.grid.ac/institutes/grid.411327.2
164 schema:familyName Gries
165 schema:givenName F. A.
166 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01320366574.43
167 rdf:type schema:Person
168 sg:person.01332010455.05 schema:affiliation https://www.grid.ac/institutes/grid.411327.2
169 schema:familyName Kolb
170 schema:givenName H.
171 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01332010455.05
172 rdf:type schema:Person
173 sg:person.0604366274.42 schema:affiliation Nef96bb92b207439aadfc74f7edfcfd1e
174 schema:familyName Henrichs
175 schema:givenName H. R.
176 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0604366274.42
177 rdf:type schema:Person
178 sg:pub.10.1007/bf00252258 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022772619
179 https://doi.org/10.1007/bf00252258
180 rdf:type schema:CreativeWork
181 sg:pub.10.1007/bf00275267 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011036776
182 https://doi.org/10.1007/bf00275267
183 rdf:type schema:CreativeWork
184 sg:pub.10.1007/bf00282516 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011393555
185 https://doi.org/10.1007/bf00282516
186 rdf:type schema:CreativeWork
187 sg:pub.10.1007/bf00282704 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041591620
188 https://doi.org/10.1007/bf00282704
189 rdf:type schema:CreativeWork
190 https://app.dimensions.ai/details/publication/pub.1083258223 schema:CreativeWork
191 https://doi.org/10.1016/s0140-6736(74)90140-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033242317
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1016/s0140-6736(76)92033-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1003477826
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1016/s0140-6736(80)92825-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045820507
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1016/s0140-6736(83)91481-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001348749
198 rdf:type schema:CreativeWork
199 https://doi.org/10.2337/diab.32.8.743 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070734411
200 rdf:type schema:CreativeWork
201 https://www.grid.ac/institutes/grid.411327.2 schema:alternateName Heinrich Heine University Düsseldorf
202 schema:name Diabetes Research Institute, University of Düsseldorf, Düsseldorf, Germany
203 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...