Ontology type: schema:ScholarlyArticle
1974-06
AUTHORSJeffrey N. Davidson, Maureen R. Hanson, Lawrence Bogorad
ABSTRACTA unified biochemical and genetic study has led to the location of the gene for erythromycin resistance in 4 mutants of Chalamydomonas reinhardi and the identification of the chloroplast ribosomal protein altered in these strains. Tetrad analyses of crosses involving the Mendelian mutants ery-M1a, ery-M1b, ery-M1c, and ery-M1d indicate that they are closely-linked alleles which map to nuclear linkage group XI. The proteins of the 52s subunits of wild-type and the 4 ery-M1 mutants were compared by one-and two-dimensional gel electrophoresis. Protein LC6 from wild-type differs in net charge at pH 5 from the homologous component found in each of the mutants. The LC6 in ery-M1b is also 30% smaller in molecular weight than the wild-type protein. The variety of altered forms of LC6 observed and the allelic nature of the genetic determinants strongly support the view that the nuclear locus for erythromycin resistance of the ery-M1 group is the structural gene for the chloroplast ribosomal protein LC6. More... »
PAGES119-129
http://scigraph.springernature.com/pub.10.1007/bf00272177
DOIhttp://dx.doi.org/10.1007/bf00272177
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1080334764
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/4421915
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Genetics",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biological Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Alleles",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Bacterial Proteins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Chlamydomonas",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Chloroplasts",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Drug Resistance, Microbial",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Erythromycin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Genes",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Genetic Linkage",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Genetics, Microbial",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hydrogen-Ion Concentration",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Molecular Biology",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Molecular Weight",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Mutation",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Harvard University",
"id": "https://www.grid.ac/institutes/grid.38142.3c",
"name": [
"The Biological Laboratories, Harvard University, Cambridge, Massachusetts"
],
"type": "Organization"
},
"familyName": "Davidson",
"givenName": "Jeffrey N.",
"id": "sg:person.050775131.02",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.050775131.02"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Harvard University",
"id": "https://www.grid.ac/institutes/grid.38142.3c",
"name": [
"The Biological Laboratories, Harvard University, Cambridge, Massachusetts"
],
"type": "Organization"
},
"familyName": "Hanson",
"givenName": "Maureen R.",
"id": "sg:person.01034441601.87",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01034441601.87"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Harvard University",
"id": "https://www.grid.ac/institutes/grid.38142.3c",
"name": [
"The Biological Laboratories, Harvard University, Cambridge, Massachusetts"
],
"type": "Organization"
},
"familyName": "Bogorad",
"givenName": "Lawrence",
"id": "sg:person.01154236031.60",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154236031.60"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1016/s0065-2660(08)60127-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001103649"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0022-2836(70)90061-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004723706"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00267699",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009655825",
"https://doi.org/10.1007/bf00267699"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00267699",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009655825",
"https://doi.org/10.1007/bf00267699"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0005-2787(66)90301-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011561416"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0005-2787(66)90301-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011561416"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0022-2836(68)90391-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1013109814"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.69.12.3779",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016347421"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0006-291x(73)90872-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016546750"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/222333a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016924231",
"https://doi.org/10.1038/222333a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00569785",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020640288",
"https://doi.org/10.1007/bf00569785"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00267704",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027112856",
"https://doi.org/10.1007/bf00267704"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00267704",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027112856",
"https://doi.org/10.1007/bf00267704"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00268742",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029149044",
"https://doi.org/10.1007/bf00268742"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00268742",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029149044",
"https://doi.org/10.1007/bf00268742"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.46.1.83",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033287370"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00269648",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034721941",
"https://doi.org/10.1007/bf00269648"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00269648",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034721941",
"https://doi.org/10.1007/bf00269648"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00337473",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041858933",
"https://doi.org/10.1007/bf00337473"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1146/annurev.ge.04.120170.002145",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042333832"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1146/annurev.mi.14.100160.001213",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044552029"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf02981648",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050236213",
"https://doi.org/10.1007/bf02981648"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf02981648",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050236213",
"https://doi.org/10.1007/bf02981648"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0003-2697(74)90065-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052976643"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.162.3853.576",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062495607"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.166.3910.1282",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062498501"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.174.4010.707",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062503827"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1076094121",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1077357543",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1080231265",
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00272176",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1080331867",
"https://doi.org/10.1007/bf00272176"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00269175",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1086027077",
"https://doi.org/10.1007/bf00269175"
],
"type": "CreativeWork"
}
],
"datePublished": "1974-06",
"datePublishedReg": "1974-06-01",
"description": "A unified biochemical and genetic study has led to the location of the gene for erythromycin resistance in 4 mutants of Chalamydomonas reinhardi and the identification of the chloroplast ribosomal protein altered in these strains. Tetrad analyses of crosses involving the Mendelian mutants ery-M1a, ery-M1b, ery-M1c, and ery-M1d indicate that they are closely-linked alleles which map to nuclear linkage group XI. The proteins of the 52s subunits of wild-type and the 4 ery-M1 mutants were compared by one-and two-dimensional gel electrophoresis. Protein LC6 from wild-type differs in net charge at pH 5 from the homologous component found in each of the mutants. The LC6 in ery-M1b is also 30% smaller in molecular weight than the wild-type protein. The variety of altered forms of LC6 observed and the allelic nature of the genetic determinants strongly support the view that the nuclear locus for erythromycin resistance of the ery-M1 group is the structural gene for the chloroplast ribosomal protein LC6.",
"genre": "research_article",
"id": "sg:pub.10.1007/bf00272177",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1297380",
"issn": [
"1617-4615",
"1432-1874"
],
"name": "Molecular Genetics and Genomics",
"type": "Periodical"
},
{
"issueNumber": "2",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "132"
}
],
"name": "An altered chloroplast ribosomal protein in ery-M1 mutants of Chlamydomonas reinhardi",
"pagination": "119-129",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"14c141e60ccf80d792a534730c1d2a64e8bf88771c95557ca0898ea7708ac711"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"4421915"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"0125036"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/bf00272177"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1080334764"
]
}
],
"sameAs": [
"https://doi.org/10.1007/bf00272177",
"https://app.dimensions.ai/details/publication/pub.1080334764"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T00:11",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8695_00000492.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007/BF00272177"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00272177'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00272177'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00272177'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00272177'
This table displays all metadata directly associated to this object as RDF triples.
220 TRIPLES
21 PREDICATES
68 URIs
34 LITERALS
22 BLANK NODES