Urinary pepsinogen isozymes: A highly polymorphic locus in man View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1979-11

AUTHORS

R. T. Taggart, R. C. Karn, A. D. Merritt, P. L. Yu, P. M. Conneally

ABSTRACT

A genetic analysis of human urinary pepsinogen isozymes is presented. Nine discrete phenotypes were identified in a population survey of 215 unrelated Caucasian individuals. The phenotypes were characterized by differences among the staining intensities of the activated group I pepsinogens, Pg 5, Pg 4, Pg 3, and Pg 2. The genetic studies demonstrated that the codominant expression of four alleles, PgA, PgB, PgC and PgD, at a single genetic locus determined the nine phenotypes identified. Linkage analysis excluded close linkage of the Pg locus with the chromosome 6 markers HLA, GLO1, and Bf. More... »

PAGES

227-238

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00271578

DOI

http://dx.doi.org/10.1007/bf00271578

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1080815614

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/511179


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