Correlation between the serine sensitivity and the derepressibility of the ilv genes in Escherichia coli relA−mutants View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1978-01

AUTHORS

Marc Uzan, Antoine Danchin

ABSTRACT

Upon addition of excess one carbon metabolites (including serine) bacteria stop growing because of isoleucine starvation. After such treatment stringent bacteria rapidly resume normal growth whereas relaxed mutants remain unable for some time to grow. We show here that this is due to a lack of derepressibility of ilv genes after the starvation period. Results are also presented which show that RNA polymerase structural mutants may be selected among the clones resistant to a mixture of serine, methionine and glycine, in relA-strains. Finally circumstancial evidence suggests that the one carbon metabolism may be involved in a process controlling isoleucine metabolism. More... »

PAGES

21-30

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00270372

DOI

http://dx.doi.org/10.1007/bf00270372

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006537046

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/362163


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0605", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA-Directed RNA Polymerases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Enzyme Repression", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Escherichia coli", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glycine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Isoleucine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Methionine", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Serine", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Institut de Biologie Physico-Chimique, 13, rue Pierre et Marie Curie, F-75005, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.450875.b", 
          "name": [
            "Institut de Biologie Physico-Chimique, 13, rue Pierre et Marie Curie, F-75005, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Uzan", 
        "givenName": "Marc", 
        "id": "sg:person.0735575626.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735575626.40"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institut de Biologie Physico-Chimique, 13, rue Pierre et Marie Curie, F-75005, Paris, France", 
          "id": "http://www.grid.ac/institutes/grid.450875.b", 
          "name": [
            "Institut de Biologie Physico-Chimique, 13, rue Pierre et Marie Curie, F-75005, Paris, France"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Danchin", 
        "givenName": "Antoine", 
        "id": "sg:person.01156273074.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156273074.10"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/978-3-662-11691-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044989041", 
          "https://doi.org/10.1007/978-3-662-11691-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/253279a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049178383", 
          "https://doi.org/10.1038/253279a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00268308", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040743415", 
          "https://doi.org/10.1007/bf00268308"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00269400", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035745221", 
          "https://doi.org/10.1007/bf00269400"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/newbio238072a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038100946", 
          "https://doi.org/10.1038/newbio238072a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00268128", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050032529", 
          "https://doi.org/10.1007/bf00268128"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00894773", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012158793", 
          "https://doi.org/10.1007/bf00894773"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1978-01", 
    "datePublishedReg": "1978-01-01", 
    "description": "Upon addition of excess one carbon metabolites (including serine) bacteria stop growing because of isoleucine starvation. After such treatment stringent bacteria rapidly resume normal growth whereas relaxed mutants remain unable for some time to grow. We show here that this is due to a lack of derepressibility of ilv genes after the starvation period. Results are also presented which show that RNA polymerase structural mutants may be selected among the clones resistant to a mixture of serine, methionine and glycine, in relA-strains. Finally circumstancial evidence suggests that the one carbon metabolism may be involved in a process controlling isoleucine metabolism.", 
    "genre": "article", 
    "id": "sg:pub.10.1007/bf00270372", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1297380", 
        "issn": [
          "1617-4615", 
          "1432-1874"
        ], 
        "name": "Molecular Genetics and Genomics", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "165"
      }
    ], 
    "keywords": [
      "ilv genes", 
      "mixture of serine", 
      "carbon metabolism", 
      "serine sensitivity", 
      "structural mutants", 
      "relaxed mutants", 
      "isoleucine starvation", 
      "Escherichia coli", 
      "normal growth", 
      "mutants", 
      "genes", 
      "isoleucine metabolism", 
      "starvation period", 
      "circumstancial evidence", 
      "bacteria", 
      "metabolism", 
      "serine", 
      "starvation", 
      "clones", 
      "coli", 
      "methionine", 
      "growth", 
      "evidence", 
      "addition", 
      "process", 
      "lack", 
      "sensitivity", 
      "results", 
      "correlation", 
      "mixture", 
      "period", 
      "time"
    ], 
    "name": "Correlation between the serine sensitivity and the derepressibility of the ilv genes in Escherichia coli relA\u2212mutants", 
    "pagination": "21-30", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1006537046"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf00270372"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "362163"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf00270372", 
      "https://app.dimensions.ai/details/publication/pub.1006537046"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2022-06-01T21:56", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220601/entities/gbq_results/article/article_106.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1007/bf00270372"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00270372'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00270372'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00270372'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00270372'


 

This table displays all metadata directly associated to this object as RDF triples.

165 TRIPLES      22 PREDICATES      75 URIs      60 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf00270372 schema:about N0a371732d9474e659e278cd737317087
2 N0d4e22956cb8461ba93996d4b79294c8
3 N648bf6a14c4840c187848cb663207a80
4 N8c3ecc7de1654779a12dd6917d249fb4
5 N8e1250e0390b423fa308296b0dd73f28
6 N94cc4a50f9df41c3a8cb315a379040a9
7 N9ddf9ef082a14b4cb9c791692eb1d5ac
8 Ncad020020ae54828902d7e9a122520b7
9 Ne21c0bb27b124d7983b788fda8846497
10 anzsrc-for:06
11 anzsrc-for:0605
12 schema:author N26febad9b8d4442fbeccc3e10f3258a7
13 schema:citation sg:pub.10.1007/978-3-662-11691-3
14 sg:pub.10.1007/bf00268128
15 sg:pub.10.1007/bf00268308
16 sg:pub.10.1007/bf00269400
17 sg:pub.10.1007/bf00894773
18 sg:pub.10.1038/253279a0
19 sg:pub.10.1038/newbio238072a0
20 schema:datePublished 1978-01
21 schema:datePublishedReg 1978-01-01
22 schema:description Upon addition of excess one carbon metabolites (including serine) bacteria stop growing because of isoleucine starvation. After such treatment stringent bacteria rapidly resume normal growth whereas relaxed mutants remain unable for some time to grow. We show here that this is due to a lack of derepressibility of ilv genes after the starvation period. Results are also presented which show that RNA polymerase structural mutants may be selected among the clones resistant to a mixture of serine, methionine and glycine, in relA-strains. Finally circumstancial evidence suggests that the one carbon metabolism may be involved in a process controlling isoleucine metabolism.
23 schema:genre article
24 schema:inLanguage en
25 schema:isAccessibleForFree false
26 schema:isPartOf N23d30b9a0e6f418da2755d5c183ecae7
27 Na3f4e737dabe47578c3b96a4dd12cb91
28 sg:journal.1297380
29 schema:keywords Escherichia coli
30 addition
31 bacteria
32 carbon metabolism
33 circumstancial evidence
34 clones
35 coli
36 correlation
37 evidence
38 genes
39 growth
40 ilv genes
41 isoleucine metabolism
42 isoleucine starvation
43 lack
44 metabolism
45 methionine
46 mixture
47 mixture of serine
48 mutants
49 normal growth
50 period
51 process
52 relaxed mutants
53 results
54 sensitivity
55 serine
56 serine sensitivity
57 starvation
58 starvation period
59 structural mutants
60 time
61 schema:name Correlation between the serine sensitivity and the derepressibility of the ilv genes in Escherichia coli relA−mutants
62 schema:pagination 21-30
63 schema:productId N134451d7f34649328b83946d99e55957
64 N583ffba2f6384fa9b1b483d7490f2663
65 N6741d747e1064dfb98641b53bedf59a7
66 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006537046
67 https://doi.org/10.1007/bf00270372
68 schema:sdDatePublished 2022-06-01T21:56
69 schema:sdLicense https://scigraph.springernature.com/explorer/license/
70 schema:sdPublisher N8894662c67e847c8986faeffe25747df
71 schema:url https://doi.org/10.1007/bf00270372
72 sgo:license sg:explorer/license/
73 sgo:sdDataset articles
74 rdf:type schema:ScholarlyArticle
75 N0a371732d9474e659e278cd737317087 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Mutation
77 rdf:type schema:DefinedTerm
78 N0d4e22956cb8461ba93996d4b79294c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
79 schema:name Glycine
80 rdf:type schema:DefinedTerm
81 N134451d7f34649328b83946d99e55957 schema:name dimensions_id
82 schema:value pub.1006537046
83 rdf:type schema:PropertyValue
84 N23d30b9a0e6f418da2755d5c183ecae7 schema:issueNumber 1
85 rdf:type schema:PublicationIssue
86 N26febad9b8d4442fbeccc3e10f3258a7 rdf:first sg:person.0735575626.40
87 rdf:rest Nc7ece010ce13411788d062d22d84a000
88 N583ffba2f6384fa9b1b483d7490f2663 schema:name doi
89 schema:value 10.1007/bf00270372
90 rdf:type schema:PropertyValue
91 N648bf6a14c4840c187848cb663207a80 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Serine
93 rdf:type schema:DefinedTerm
94 N6741d747e1064dfb98641b53bedf59a7 schema:name pubmed_id
95 schema:value 362163
96 rdf:type schema:PropertyValue
97 N8894662c67e847c8986faeffe25747df schema:name Springer Nature - SN SciGraph project
98 rdf:type schema:Organization
99 N8c3ecc7de1654779a12dd6917d249fb4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name DNA-Directed RNA Polymerases
101 rdf:type schema:DefinedTerm
102 N8e1250e0390b423fa308296b0dd73f28 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Enzyme Repression
104 rdf:type schema:DefinedTerm
105 N94cc4a50f9df41c3a8cb315a379040a9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Genes
107 rdf:type schema:DefinedTerm
108 N9ddf9ef082a14b4cb9c791692eb1d5ac schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Escherichia coli
110 rdf:type schema:DefinedTerm
111 Na3f4e737dabe47578c3b96a4dd12cb91 schema:volumeNumber 165
112 rdf:type schema:PublicationVolume
113 Nc7ece010ce13411788d062d22d84a000 rdf:first sg:person.01156273074.10
114 rdf:rest rdf:nil
115 Ncad020020ae54828902d7e9a122520b7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
116 schema:name Methionine
117 rdf:type schema:DefinedTerm
118 Ne21c0bb27b124d7983b788fda8846497 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Isoleucine
120 rdf:type schema:DefinedTerm
121 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
122 schema:name Biological Sciences
123 rdf:type schema:DefinedTerm
124 anzsrc-for:0605 schema:inDefinedTermSet anzsrc-for:
125 schema:name Microbiology
126 rdf:type schema:DefinedTerm
127 sg:journal.1297380 schema:issn 1432-1874
128 1617-4615
129 schema:name Molecular Genetics and Genomics
130 schema:publisher Springer Nature
131 rdf:type schema:Periodical
132 sg:person.01156273074.10 schema:affiliation grid-institutes:grid.450875.b
133 schema:familyName Danchin
134 schema:givenName Antoine
135 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01156273074.10
136 rdf:type schema:Person
137 sg:person.0735575626.40 schema:affiliation grid-institutes:grid.450875.b
138 schema:familyName Uzan
139 schema:givenName Marc
140 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735575626.40
141 rdf:type schema:Person
142 sg:pub.10.1007/978-3-662-11691-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044989041
143 https://doi.org/10.1007/978-3-662-11691-3
144 rdf:type schema:CreativeWork
145 sg:pub.10.1007/bf00268128 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050032529
146 https://doi.org/10.1007/bf00268128
147 rdf:type schema:CreativeWork
148 sg:pub.10.1007/bf00268308 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040743415
149 https://doi.org/10.1007/bf00268308
150 rdf:type schema:CreativeWork
151 sg:pub.10.1007/bf00269400 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035745221
152 https://doi.org/10.1007/bf00269400
153 rdf:type schema:CreativeWork
154 sg:pub.10.1007/bf00894773 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012158793
155 https://doi.org/10.1007/bf00894773
156 rdf:type schema:CreativeWork
157 sg:pub.10.1038/253279a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049178383
158 https://doi.org/10.1038/253279a0
159 rdf:type schema:CreativeWork
160 sg:pub.10.1038/newbio238072a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038100946
161 https://doi.org/10.1038/newbio238072a0
162 rdf:type schema:CreativeWork
163 grid-institutes:grid.450875.b schema:alternateName Institut de Biologie Physico-Chimique, 13, rue Pierre et Marie Curie, F-75005, Paris, France
164 schema:name Institut de Biologie Physico-Chimique, 13, rue Pierre et Marie Curie, F-75005, Paris, France
165 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...