Serum lipids and lipoproteins in patients with primary gout View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1985-01

AUTHORS

A. Ulreich, G. M. Kostner, K. P. Pfeiffer, P. Sedlmayr, F. Rainer

ABSTRACT

Serum lipid and lipoprotein values of 32 male patients suffering from gout were quantitated and compared with corresponding values of a random control group which did not differ significantly with regard to age, body weight index and socio-economic status. All patients were on therapy with allopurinol which lasted on average for 6 years. The most striking differences between patients and controls were the increased triglyceride and apo B values and the decreased HDL-cholesterol (HDL-C) and HDL-phospholipid (HDL-PL) values in the patient group. The values of total cholesterol, LDL-cholesterol, apo A-I and Lp (a) were not significantly different between patients and controls. The great differences in the ratios of apo B/LDL-C, apo A-I/HDL-C and apo A-I/HDL-PL values suggest that gout is connected with changes in the chemical composition of the major lipoprotein classes. In three normolipemic individuals who were treated for 3 weeks with allopurinol no changes in lipoproteins and apolipoproteins were apparent. The results are discussed in view of the atherosclerosis risk of patients suffering from gout. More... »

PAGES

73-77

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00270300

DOI

http://dx.doi.org/10.1007/bf00270300

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1035338770

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3983533


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