Protease production by Bacillus subtilis in oxygen-controlled, glucose fed-batch fermentations View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1988-06

AUTHORS

Manoj M. Kole, Indira Draper, Donald F. Gerson

ABSTRACT

An open-loop, on-off control system using the dissolved oxygen level to control a glucose feed was used in a study of growth and production of protease by Bacillus subtilis CNIB 8054. With this system, both glucose and oxygen were controlled at low concentrations. In batch fermentations, protease activity in the fermentation broth was maximum when growth had stopped. During oxygen-controlled, glucose fed-batch fermentations, growth and the production of protease activity continued during glucose feeding. Oxygen-controlled, glucose fed-batch fermentations produced more protease activity than batch fermentations, depending upon the set point for dissolved oxygen. These results indicate that control of glucose and oxygen concentrations can result in improvements in protease production. More... »

PAGES

404-408

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00268204

DOI

http://dx.doi.org/10.1007/bf00268204

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1002608861


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