Reversion of a streptomycin-dependent strain ofEscherichia coli View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1970-12

AUTHORS

E. A. Birge, C. G. Kuriland

ABSTRACT

A streptomycin dependent, spectinomycin resistant mutant ofEscherichia coli was used to select spontaneous phenotypic revertants to non-dependence on streptomycin. The ribosomes from one such revertant, which is inhibited by both streptomycin and spectinomycin, were analyzedin vitro. The altered protein responsible for the suppression of the streptomycin dependent phenotype was identified; this protein is 30S-10. The genetic locus for this mutation is a newly identified locus and it has been positioned close to thestr locus. The identification of the altered component responsible for the suppression of the spectinomycin resistant phenotype may be the same as that for the streptomycin dependent phenotype, but this is unproven. More... »

PAGES

356-369

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00267704

DOI

http://dx.doi.org/10.1007/bf00267704

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1027112856

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4925047


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