Genetic analysis of two genes, dnaJ and dnaK, necessary for Escherichia coli and bacteriophage lambda DNA replication View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1978-01

AUTHORS

J. Yochem, H. Uchida, M. Sunshine, H. Saito, C. P. Georgopoulos, M. Feiss

ABSTRACT

We show that a collection of 93 E. coli mutations which map between thr and leu and which block phage lambda DNA replication define two closely linked cistrons. Work published in the accompanying paper shows that these mutations also affect host DNA replication, so we designate them dnaJ and dnaK; the gene order is thr-dnaK-dnaJ-leu. Demonstration of two cistrons was possible with the isolation of lambda transducing phages carrying one or the other or both of the dna genes. These phages were employed in phage vs bacterial complementation studies which unambiguously show that dnaK and dnaJ are different cistrons. More... »

PAGES

9-14

References to SciGraph publications

  • 1977-01. A new bacterial gene (groPC) which affects λ DNA replication in MOLECULAR GENETICS AND GENOMICS
  • 1978-01. Organization and expression of the dnaJ and dnaK genes of Escherichia coli K12 in MOLECULAR GENETICS AND GENOMICS
  • 1974-09. Mutational specificity of a conditional Escherichia coli mutator, mutD5 in MOLECULAR GENETICS AND GENOMICS
  • 1977-01. A new host gene (groPC) necessary for lambda DNA replication in MOLECULAR GENETICS AND GENOMICS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf00267593

    DOI

    http://dx.doi.org/10.1007/bf00267593

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1000460916

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/360041


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