Reactivation of a silent Ac following tissue culture is associated with heritable alterations in its methylation pattern View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1991-10

AUTHORS

Richard I.S. Brettell, Elizabeth S. Dennis

ABSTRACT

Tissue cultures were initiated from embryos with an inactive form of Ac in the wx-m9 Ds-cy allele. Plants regenerated from the cultures showed a high frequency of activation of Ac. That activation was shown to be associated with reduced methylation of cytosine residues at the 5′ end of the transposable element. An examination of Ac activity and methylation status of the Ac element in progenies of the regenerant plants demonstrated transmission of the altered epigenotype through two sexual generations. In these progenies no evidence for trans activation of inactive, partially methylated, Ac elements was obtained. These results confirm that in certain instances altered methylation patterns can be inherited through the germ line. More... »

PAGES

365-372

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00267457

DOI

http://dx.doi.org/10.1007/bf00267457

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034300351

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1658596


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