The ten-year follow-up of the Bedford Survey (1962–1972): Glucose tolerance and diabetes View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1982-02

AUTHORS

H. Keen, R. J. Jarrett, P. McCartney

ABSTRACT

In a 10-year prospective study of 241 people with ‘borderline diabetes” (impaired glucose tolerance) identified by screening of the Bedford adult population, 36 (15%) worsened to diabetes and 128 (53%) substantially improved their glucose tolerance. The major predictor of worsening to diabetes was the level of blood glucose at baseline. This was statistically significant (p < 0.05), independent of other factors, both for deterioration in the first and in the second five years of observation. Body mass index, a measure of adiposity, did not predict worsening to diabetes during the first five years, but was an independent and significant predictor of worsening during the second five years (p < 0.05). The apparent effect of adiposity was complex, for it was also significantly related to improvement in glucose tolerance during the 10-year follow-up. Persons with impaired glucose tolerance are a heterogeneous group and with present knowledge the ability to predict metabolic deterioration is limited. More... »

PAGES

73-78

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00254832

DOI

http://dx.doi.org/10.1007/bf00254832

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1043782894

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/7060852


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