Lymphocyte subsets in urologic cancer patients View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1987-06

AUTHORS

M. Shaw, P. Ray, M. Rubenstein, P. Guinan

ABSTRACT

Peripheral blood T lymphocyte subsets were quantitated by monoclonal antibodies in 91 patients with urologic malignancies as well as eight age-matched controls. In general, the presence of cancer and increasing stage were associated with a relative decrease in helper and an increase in suppressor T-cell activity as well as a decreased T4/T8 cell ratio. Therapy in the form of androgen depletion reversed these trends and restored helper and suppressor levels as well as the T4/T8 ratio to control values. In a small subset of sixteen patients surgery had only modest immediate (prostate) and long term (kidney) effects on these parameters. More... »

PAGES

181-185

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00254434

DOI

http://dx.doi.org/10.1007/bf00254434

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040186815

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2957843


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