Ontology type: schema:ScholarlyArticle
1988-04
AUTHORSWei-Jen Shih, John J. Coupal, Marcus L. Dillon, Hank F. Kung
ABSTRACTN,N,N'-Trimethyl-N'-(2-Hydroxyl-3-Methyl-5-123I Iodobenzyl)-1,3-Propanediamine.Hcl (123I-HIPDM) has been used for diagnosis of patients with strokes and dementias. Since this radiopharmaceutical is also accumulated in the lung, we routinely performed a lung image or images immediately prior to cerebral planar and SPECT images after a 3-5 mCi 123I-HIPDM injection. During the past 14 months, we obtained 78 (age from 41 to 92 years, average 66.7 +/- 8.9 years; 64 males, 14 females) suspected stroke or dementia patients' lung images. All lung images were correlated to chest X-ray (CXR) or CT and other clinical data. Sixty five of 78 patients had normal lungs showing homogeneous distribution of activity throughout the lungs which correlated well to normal CXR and/or CT studies. Abnormal scintigraphic patterns of the 13 patients included lung defect (5 bronchogenic carcinoma with or without atelectasis) and decreased uptake in apices (8 chronic obstructive pulmonary disease). The findings of pulmonary intrathoracic pathologies on lung images with 123I-HIPDM suggests further evaluation of the agent for detection of localized pulmonary diseases and pulmonary physiological studies relating to amine metabolism. More... »
PAGES21-24
http://scigraph.springernature.com/pub.10.1007/bf00252612
DOIhttp://dx.doi.org/10.1007/bf00252612
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1035296506
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/3383904
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1102",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Cardiorespiratory Medicine and Haematology",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adult",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Aged, 80 and over",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Carcinoma, Bronchogenic",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Female",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Iodobenzenes",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Lung",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Lung Diseases, Obstructive",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Lung Neoplasms",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Male",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Middle Aged",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Radionuclide Imaging",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University of Kentucky",
"id": "https://www.grid.ac/institutes/grid.266539.d",
"name": [
"VA and University of Kentucky Medical Centers, 40536, Lexington, KY, USA"
],
"type": "Organization"
},
"familyName": "Shih",
"givenName": "Wei-Jen",
"id": "sg:person.011766530162.55",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011766530162.55"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Kentucky",
"id": "https://www.grid.ac/institutes/grid.266539.d",
"name": [
"VA and University of Kentucky Medical Centers, 40536, Lexington, KY, USA"
],
"type": "Organization"
},
"familyName": "Coupal",
"givenName": "John J.",
"id": "sg:person.01051513007.20",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051513007.20"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Kentucky",
"id": "https://www.grid.ac/institutes/grid.266539.d",
"name": [
"VA and University of Kentucky Medical Centers, 40536, Lexington, KY, USA"
],
"type": "Organization"
},
"familyName": "Dillon",
"givenName": "Marcus L.",
"id": "sg:person.07643324152.99",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07643324152.99"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Penn Presbyterian Medical Center",
"id": "https://www.grid.ac/institutes/grid.412713.2",
"name": [
"Division of Nuclear Medicine, University of Pennsylvania Medical Center, 19104, Philadelphia, PA, USA"
],
"type": "Organization"
},
"familyName": "Kung",
"givenName": "Hank F.",
"id": "sg:person.0615735606.55",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0615735606.55"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1146/annurev.pa.26.040186.001151",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008951253"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1001/archneur.1984.04050210058015",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015567536"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1146/annurev.pa.25.040185.000525",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043098858"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1146/annurev.ph.44.030182.001413",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053409808"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1055/s-2007-1011432",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057484193"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1148/radiology.158.3.3484833",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1079778519"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1080104693",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081708326",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081725474",
"type": "CreativeWork"
}
],
"datePublished": "1988-04",
"datePublishedReg": "1988-04-01",
"description": "N,N,N'-Trimethyl-N'-(2-Hydroxyl-3-Methyl-5-123I Iodobenzyl)-1,3-Propanediamine.Hcl (123I-HIPDM) has been used for diagnosis of patients with strokes and dementias. Since this radiopharmaceutical is also accumulated in the lung, we routinely performed a lung image or images immediately prior to cerebral planar and SPECT images after a 3-5 mCi 123I-HIPDM injection. During the past 14 months, we obtained 78 (age from 41 to 92 years, average 66.7 +/- 8.9 years; 64 males, 14 females) suspected stroke or dementia patients' lung images. All lung images were correlated to chest X-ray (CXR) or CT and other clinical data. Sixty five of 78 patients had normal lungs showing homogeneous distribution of activity throughout the lungs which correlated well to normal CXR and/or CT studies. Abnormal scintigraphic patterns of the 13 patients included lung defect (5 bronchogenic carcinoma with or without atelectasis) and decreased uptake in apices (8 chronic obstructive pulmonary disease). The findings of pulmonary intrathoracic pathologies on lung images with 123I-HIPDM suggests further evaluation of the agent for detection of localized pulmonary diseases and pulmonary physiological studies relating to amine metabolism.",
"genre": "research_article",
"id": "sg:pub.10.1007/bf00252612",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isFundedItemOf": [
{
"id": "sg:grant.2670550",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1297401",
"issn": [
"1619-7070",
"1619-7089"
],
"name": "European Journal of Nuclear Medicine and Molecular Imaging",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "14"
}
],
"name": "Application of I-123 HIPDM as a lung imaging agent",
"pagination": "21-24",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"a822f6f20722076108870637a790487dce887ab4cb8b86e7dfd838b9ae1b8499"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"3383904"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"7606882"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/bf00252612"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1035296506"
]
}
],
"sameAs": [
"https://doi.org/10.1007/bf00252612",
"https://app.dimensions.ai/details/publication/pub.1035296506"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T14:00",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000371_0000000371/records_130829_00000003.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007/BF00252612"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00252612'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00252612'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00252612'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00252612'
This table displays all metadata directly associated to this object as RDF triples.
171 TRIPLES
21 PREDICATES
51 URIs
34 LITERALS
22 BLANK NODES