Triterpenoid biosynthesis in tissue cultures of Glycyrrhiza glabra var. glandulifera View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1990-08

AUTHORS

S. Ayabe, H. Takano, T. Fujita, T. Furuya, H. Hirota, T. Takahashi

ABSTRACT

The incorporation of [1-(14)C]acetate and [2(14) C]mevalonate into free and esterified triterpen-3-ols was examined in original plant organs and tissue cultures of Glycyrrhiza glabra var. glandulifera. Both substrates labeled β-amyrin, an oleanane-type triterpene, and cycloartenol and 24-methylenecycloartanol, both of which are intermediates of phytosterol biosynthesis. The label in esterified triterpenes was distributed mainly in phytosterol intermediates, but not in β-amyrin. The ratio of βamyrin formation among the three triterpenes from [2-(14)C]mevalonate was relatively high in stolon segments and in root cultures, but negligible in callus cultures. Administration of a specific inhibitor of squalene-2, 3-epoxide:cycloartenol (lanosterol) cyclase caused a marked increase of β-amyrin synthesis in root suspension cultures, and of 24-methylenecycloartanol synthesis in cell suspension cultures, from [2-(14)C]mevalonate. More... »

PAGES

181-184

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00232175

DOI

http://dx.doi.org/10.1007/bf00232175

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1015819069

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24226698


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