Monoclonal antibody VC1.1 selectively stains a population of GABAergic neurons containing the calcium-binding protein parvalbumin in the rat cerebral cortex View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1989-11

AUTHORS

T. Kosaka, C. W. Heizmann, C. J. Barnstable

ABSTRACT

Monoclonal antibody VC1.1 is shown to stain selectively a subpopulation of GABAergic neurons in the rat cerebral cortex. Almost all VC1.1 immunoreactive cells were also GABA-like immunoreactive (GABA-LI) and parvalbumin (PV) immunoreactive, whereas they were about 30% and 65% of GABA-LI and PV-positive cells in the parietal cortex and about 13% and 32% in the occipital cortex, respectively. Although a few VC1.1 positive cells showed somatostatin-like and/or cholecystokinin-like immunoreactivities, they were exceptional (less than 1% of VC1.1 positive cells). Furthermore about 90% of VC1.1 positive cells were also stained with a lectin, Vicia villosa agglutinin, with a specific affinity for terminal N-acetylgalactosamine. More... »

PAGES

43-50

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00230685

DOI

http://dx.doi.org/10.1007/bf00230685

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018231558

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2591517


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