Estimation, variance and optimal sampling of gene diversity II. Diploid locus View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1995-07

AUTHORS

O. Pons, K. Chaouche

ABSTRACT

Nei's analysis of diversity at a diploid locus is extended to a population subdivided into a large number of subpopulations. The diversities and the heterozygotes frequency are defined with respect to the total population and unbiasedly estimated in a two-stage random cluster sampling. The fixation indices F IS, F IT andF ST are derived, then inter- and intra-population variances of the estimated parameters are studied. We show that there is a unique sample size per population which yields the best accuracy in estimatingF ST and F IS, respectively, at a given locus. These results are illustrated with an analysis of DNA diversity in a forest tree and compared to those obtained under the Hardy-Weinberg assumption. More... »

PAGES

122-130

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00220868

DOI

http://dx.doi.org/10.1007/bf00220868

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006375477

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24169677


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