The interaction between calcium and the activation of Na+, K+-ATPase by noradrenaline View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1985-03

AUTHORS

Marianne Haaga, Wieland Gevers, Reinhard G. Böhmer

ABSTRACT

The interaction of noradrenaline, various cation chelators and calcium on Na+, K+-ATPase from rat cerebral cortex plasma membranes was studied. It was shown that chelation of inhibitory cations by EGTA, EDTA and dipyridyl activated Na+, K+-ATPase to the same extent as noradrenaline but at higher concentrations; increasing concentrations of EGTA depressed the activation by noradrenaline; calcium in the form of a calcium-EGTA buffer depressed Na+, K+-ATPase at physiological concentrations; the inhibition of Na+, K+-ATPase by calcium is dependent on the magnesium concentration in the assay and the inhibition by calcium was partially reversed by noradrenaline. More... »

PAGES

111-116

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00220778

DOI

http://dx.doi.org/10.1007/bf00220778

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1023098920

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2984541


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