Immunoreactive ACTH/β-endorphin neurons in the tubero-infundibular hypothalamus of rats View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1982-05

AUTHORS

Setsuji Hisano, Hitoshi Kawano, Tohru Nishiyama, Shigeo Daikoku

ABSTRACT

In the preinfundibular portion of male rat hypothalamus, the arcuate-median eminence region was examined after staining with anti-porcine ACTH 1-39 serum. In several cases, anti-β-endorphin serum was also employed. Both sera stain the same cell bodies. The cell bodies of the immunoreactive neurons are scattered in the subependymal layer, arcuate nucleus and lateral tuberal region. Fibers originating from these cell bodies are distributed extensively throughout these regions. They make synaptic contacts on immunonegative fibers in the arcuate nuclei, or terminate directly in the perivascular space in the internal layer of the median eminence. The fibers, however, are very scarce in the external layer of the median eminence, and do not directly terminate on the neurovascular contact surface. These findings suggest that the ACTH/β-endorphin neuronal system may serve neuronally and humorally as an intrahypothalamic constituent of the hypothalamic pituitary regulation system. More... »

PAGES

303-314

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00216875

DOI

http://dx.doi.org/10.1007/bf00216875

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1037058316

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6286129


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