Kinetics of subtilisin and thiolsubtilisin View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1983-03

AUTHORS

M. Philipp, M. L. Bender

ABSTRACT

Subtilisin is a bacterial serine protease with a broad specificity in the S1 subsite. It has been very extensively studied using a variety of kinetic and physical techniques. A chemical derivative, thiolsubtilisin, has been subjected to similar studies in order to analyze the effects of the OH to SH conversion on enzyme activity. The native structure of thiolsubtilisin is indicated by a variety of physical techniques. Oligopeptides bind nearly equally well to both enzymes, and a peptide chloromethylketone is much more reactive to thiolsubtilisin than to subtilisin. Both enzymes have a similar level of activity towards activated nonspecific amides and esters. However, thiolsubtilisin is inactive towards highly specific peptide amides and esters. Thiolsubtilisin also does not show good binding to boronic and arsonic acids. The observation that these transition state analog inhibitors bind poorly to thiolsubtilisin while other compounds bind nearly equally well to both enzymes suggests that thiolsubtilisin may not be able to stabilize the transition state during acylation by specific substrates. More... »

PAGES

5-32

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00215583

DOI

http://dx.doi.org/10.1007/bf00215583

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1020119678

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6343835


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0302", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Inorganic Chemistry", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Acylation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amides", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Imidazoles", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kinetics", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Substrate Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Subtilisins", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "name": [
            "Dept. of Chemistry, Lehman College of the City University of New York, and Dept. of Biochemistry, Graduate Center of CUNY, 60201, Evanston, IL, U.S.A."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Philipp", 
        "givenName": "M.", 
        "id": "sg:person.01000541074.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01000541074.97"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Northwestern University", 
          "id": "https://www.grid.ac/institutes/grid.16753.36", 
          "name": [
            "Depts. of Biochemistry and Chemistry, Northwestern University, 60201, Evanston, IL, U.S.A."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bender", 
        "givenName": "M. L.", 
        "id": "sg:person.0104401344.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0104401344.68"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0005-2744(72)90248-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000233710"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2744(72)90248-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000233710"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-87966-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001430690", 
          "https://doi.org/10.1007/978-3-642-87966-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-87966-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001430690", 
          "https://doi.org/10.1007/978-3-642-87966-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1260645", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001738859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1260645", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001738859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1976.tb11146.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002576403"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-291x(71)90107-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002775441"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2744(76)90171-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004638419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2744(76)90171-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004638419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-87966-1_66", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004867027", 
          "https://doi.org/10.1007/978-3-642-87966-1_66"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/p29720000272", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005056398"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-291x(76)91133-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005231584"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1010056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005244784"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1010056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005244784"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(72)90479-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005462235"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1979.tb04269.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007081526"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1971.tb01589.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007493123"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/bchm2.1980.361.2.1841", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008056228"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bit.260171208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009280678"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(81)80465-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009892541"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(78)80763-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010200131"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(70)90377-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011129418"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(75)90310-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011752684"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02906260", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011822303", 
          "https://doi.org/10.1007/bf02906260"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02906260", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011822303", 
          "https://doi.org/10.1007/bf02906260"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2744(77)90338-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011879647"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2744(77)90338-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011879647"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1930819", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014308882"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1930819", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014308882"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3011.1972.tb03394.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014772912"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3011.1972.tb03394.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014772912"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(77)80754-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015243925"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(73)80629-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015286584"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1470411", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015374430"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1470411", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015374430"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0305-0491(72)90319-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016673931"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0305-0491(72)90319-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016673931"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijch.197400039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016820404"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1170341", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017142306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1170341", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017142306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.bi.34.070165.000405", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018203828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/m64-122", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018213569"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-291x(71)90002-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019588878"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1972.tb01754.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019632595"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0031-9422(80)85105-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020113751"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/277447a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020540384", 
          "https://doi.org/10.1038/277447a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.70.2.517", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020657463"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(74)90179-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020812897"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1271/bbb1961.40.1479", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022020464"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1973.tb03140.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023806024"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.64.4.1335", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024832215"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(71)90362-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026309453"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.56.5.1606", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027331584"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(66)90073-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027366167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1977.tb11832.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027376969"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(72)90391-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027664796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1260659", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028295661"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1260659", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028295661"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2795(81)90201-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029078692"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2795(81)90201-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029078692"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.65.4.1120", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029523405"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(74)80746-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031919644"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.50.5.931", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032149936"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0003-9861(71)80067-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033288193"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/b978-0-12-211850-0.50019-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033425101"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2744(78)90178-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035339591"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2744(78)90178-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035339591"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2744(78)90238-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035421356"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2744(78)90238-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035421356"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/newbio241044a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037749760", 
          "https://doi.org/10.1038/newbio241044a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/newbio241044a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037749760", 
          "https://doi.org/10.1038/newbio241044a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/newbio241044a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037749760", 
          "https://doi.org/10.1038/newbio241044a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(73)80824-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039138990"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0305-0491(74)90132-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039364719"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0305-0491(74)90132-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039364719"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01384275", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039915656", 
          "https://doi.org/10.1007/bf01384275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01384275", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039915656", 
          "https://doi.org/10.1007/bf01384275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.59.3.996", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040176994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-291x(75)90860-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040698808"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1170333", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040838092"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1170333", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040838092"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2744(78)90335-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042734786"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2744(78)90335-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042734786"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-291x(69)90269-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042778413"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-291x(67)80055-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042897284"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/bchm2.1972.353.2.1646", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043065836"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/bchm2.1972.353.2.1646", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043065836"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.70.4.1132", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044007770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(77)90183-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044328649"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(79)90205-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047331759"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/9780470122709.ch1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047336202"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/o69-155", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047480793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(70)90376-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049687326"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(74)90143-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050400824"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(69)90223-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052034462"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-3002(55)90280-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052131120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-3002(55)90280-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052131120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-4165(66)90137-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052287479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-4165(66)90137-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052287479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2744(73)90207-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053003135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2744(73)90207-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053003135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.68.2.478", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053429841"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00525a013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055179447"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00572a030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055181226"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00584a019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055181671"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00584a020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055181672"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00627a007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055183182"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00699a006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055185701"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00712a019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055186140"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00729a008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055186664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00738a002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055186935"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00763a009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055187777"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00773a016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055188062"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00789a008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055188555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00826a003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055189638"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00829a019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055189732"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00833a039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055189985"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00854a032", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055191167"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00869a020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055191827"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00876a049", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055192177"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00882a021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055192350"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00885a018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055192451"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00911a022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055193372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ed044p84", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055444755"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja00768a029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055746255"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja00786a054", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055747787"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja00872a023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055754176"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja00965a060", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055757626"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja00976a034", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055758419"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja01059a049", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055764927"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja01072a015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055765868"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja01079a027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055766585"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja01492a058", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055801549"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jo00979a005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055994201"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/o59-157", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062892878"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3891/acta.chem.scand.08-0356", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071486955"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a132157", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074399355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a131303", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074424389"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074932665", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075205893", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075525105", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075795792", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075969784", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076611542", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a131660", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077900772"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a131580", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1077949088"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078443435", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a130777", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078763093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a130799", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078763130"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078793682", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079085234", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a132236", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079619135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080519462", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a130251", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080573759"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a130292", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080575217"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a130311", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080575226"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a132555", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080596745"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a130158", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080608223"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080611940", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080711661", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080713970", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080714763", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080716869", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080720473", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080721294", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080723340", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080723716", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080727910", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080731835", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081007329", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a130947", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1081064275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081247499", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081275765", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081549534", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081957980", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082025656", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a131036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1082408761"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a131800", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083127081"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a126856", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083479695"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a126894", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083479713"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a126948", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083479732"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1983-03", 
    "datePublishedReg": "1983-03-01", 
    "description": "Subtilisin is a bacterial serine protease with a broad specificity in the S1 subsite. It has been very extensively studied using a variety of kinetic and physical techniques. A chemical derivative, thiolsubtilisin, has been subjected to similar studies in order to analyze the effects of the OH to SH conversion on enzyme activity. The native structure of thiolsubtilisin is indicated by a variety of physical techniques. Oligopeptides bind nearly equally well to both enzymes, and a peptide chloromethylketone is much more reactive to thiolsubtilisin than to subtilisin. Both enzymes have a similar level of activity towards activated nonspecific amides and esters. However, thiolsubtilisin is inactive towards highly specific peptide amides and esters. Thiolsubtilisin also does not show good binding to boronic and arsonic acids. The observation that these transition state analog inhibitors bind poorly to thiolsubtilisin while other compounds bind nearly equally well to both enzymes suggests that thiolsubtilisin may not be able to stabilize the transition state during acylation by specific substrates.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1007/bf00215583", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2381527", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1016672", 
        "issn": [
          "0300-8177", 
          "1573-4919"
        ], 
        "name": "Molecular and Cellular Biochemistry", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "1", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "51"
      }
    ], 
    "name": "Kinetics of subtilisin and thiolsubtilisin", 
    "pagination": "5-32", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/bf00215583"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "5fdcef725185653f39fa74da3c0a5683a29b781460d5ec69c8e8f59258e7c8c3"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1020119678"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0364456"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "6343835"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1007/bf00215583", 
      "https://app.dimensions.ai/details/publication/pub.1020119678"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-15T08:58", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000375_0000000375/records_91428_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://link.springer.com/10.1007/BF00215583"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00215583'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00215583'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00215583'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00215583'


 

This table displays all metadata directly associated to this object as RDF triples.

555 TRIPLES      21 PREDICATES      192 URIs      28 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/bf00215583 schema:about N0e8e6b5118834c3b823a319dd44b8692
2 N47cb90a4571c4bdaac8eb949ae2f0d9a
3 N742d16d3391645b9831854324a8b6287
4 N91a5e0f91e6c4d0b95f455c15f9d91ef
5 Nac25b148a9ca4b5bb8ad57439faaff97
6 Nd7b4c46aa1224ab68d937377c2e45a87
7 Nf93d494e1baa4df088cd38a2c7069cc4
8 anzsrc-for:03
9 anzsrc-for:0302
10 schema:author Na210fd11c15b4ce3b7a86b27c740559c
11 schema:citation sg:pub.10.1007/978-3-642-87966-1
12 sg:pub.10.1007/978-3-642-87966-1_66
13 sg:pub.10.1007/bf01384275
14 sg:pub.10.1007/bf02906260
15 sg:pub.10.1038/277447a0
16 sg:pub.10.1038/newbio241044a0
17 https://app.dimensions.ai/details/publication/pub.1074932665
18 https://app.dimensions.ai/details/publication/pub.1075205893
19 https://app.dimensions.ai/details/publication/pub.1075525105
20 https://app.dimensions.ai/details/publication/pub.1075795792
21 https://app.dimensions.ai/details/publication/pub.1075969784
22 https://app.dimensions.ai/details/publication/pub.1076611542
23 https://app.dimensions.ai/details/publication/pub.1078443435
24 https://app.dimensions.ai/details/publication/pub.1078793682
25 https://app.dimensions.ai/details/publication/pub.1079085234
26 https://app.dimensions.ai/details/publication/pub.1080519462
27 https://app.dimensions.ai/details/publication/pub.1080611940
28 https://app.dimensions.ai/details/publication/pub.1080711661
29 https://app.dimensions.ai/details/publication/pub.1080713970
30 https://app.dimensions.ai/details/publication/pub.1080714763
31 https://app.dimensions.ai/details/publication/pub.1080716869
32 https://app.dimensions.ai/details/publication/pub.1080720473
33 https://app.dimensions.ai/details/publication/pub.1080721294
34 https://app.dimensions.ai/details/publication/pub.1080723340
35 https://app.dimensions.ai/details/publication/pub.1080723716
36 https://app.dimensions.ai/details/publication/pub.1080727910
37 https://app.dimensions.ai/details/publication/pub.1080731835
38 https://app.dimensions.ai/details/publication/pub.1081007329
39 https://app.dimensions.ai/details/publication/pub.1081247499
40 https://app.dimensions.ai/details/publication/pub.1081275765
41 https://app.dimensions.ai/details/publication/pub.1081549534
42 https://app.dimensions.ai/details/publication/pub.1081957980
43 https://app.dimensions.ai/details/publication/pub.1082025656
44 https://doi.org/10.1002/9780470122709.ch1
45 https://doi.org/10.1002/bit.260171208
46 https://doi.org/10.1002/ijch.197400039
47 https://doi.org/10.1016/0003-9861(66)90073-7
48 https://doi.org/10.1016/0003-9861(69)90223-9
49 https://doi.org/10.1016/0003-9861(70)90376-0
50 https://doi.org/10.1016/0003-9861(70)90377-2
51 https://doi.org/10.1016/0003-9861(71)90362-6
52 https://doi.org/10.1016/0003-9861(74)90143-x
53 https://doi.org/10.1016/0003-9861(75)90310-0
54 https://doi.org/10.1016/0003-9861(77)90183-7
55 https://doi.org/10.1016/0005-2744(72)90248-3
56 https://doi.org/10.1016/0005-2744(73)90207-6
57 https://doi.org/10.1016/0005-2744(76)90171-6
58 https://doi.org/10.1016/0005-2744(77)90338-2
59 https://doi.org/10.1016/0005-2744(78)90178-x
60 https://doi.org/10.1016/0005-2744(78)90238-3
61 https://doi.org/10.1016/0005-2744(78)90335-2
62 https://doi.org/10.1016/0005-2795(81)90201-4
63 https://doi.org/10.1016/0006-291x(69)90269-1
64 https://doi.org/10.1016/0006-291x(71)90002-7
65 https://doi.org/10.1016/0006-291x(71)90107-0
66 https://doi.org/10.1016/0006-291x(75)90860-8
67 https://doi.org/10.1016/0006-291x(76)91133-5
68 https://doi.org/10.1016/0006-3002(55)90280-8
69 https://doi.org/10.1016/0014-5793(73)80629-5
70 https://doi.org/10.1016/0014-5793(73)80824-5
71 https://doi.org/10.1016/0014-5793(74)80746-5
72 https://doi.org/10.1016/0014-5793(77)80754-0
73 https://doi.org/10.1016/0014-5793(78)80763-7
74 https://doi.org/10.1016/0014-5793(81)80465-6
75 https://doi.org/10.1016/0022-2836(72)90391-9
76 https://doi.org/10.1016/0022-2836(72)90479-2
77 https://doi.org/10.1016/0022-2836(74)90179-x
78 https://doi.org/10.1016/0022-2836(79)90205-5
79 https://doi.org/10.1016/0031-9422(80)85105-3
80 https://doi.org/10.1016/0304-4165(66)90137-1
81 https://doi.org/10.1016/0305-0491(72)90319-7
82 https://doi.org/10.1016/0305-0491(74)90132-1
83 https://doi.org/10.1016/b978-0-12-211850-0.50019-7
84 https://doi.org/10.1016/s0003-9861(71)80067-x
85 https://doi.org/10.1016/s0006-291x(67)80055-x
86 https://doi.org/10.1021/bi00525a013
87 https://doi.org/10.1021/bi00572a030
88 https://doi.org/10.1021/bi00584a019
89 https://doi.org/10.1021/bi00584a020
90 https://doi.org/10.1021/bi00627a007
91 https://doi.org/10.1021/bi00699a006
92 https://doi.org/10.1021/bi00712a019
93 https://doi.org/10.1021/bi00729a008
94 https://doi.org/10.1021/bi00738a002
95 https://doi.org/10.1021/bi00763a009
96 https://doi.org/10.1021/bi00773a016
97 https://doi.org/10.1021/bi00789a008
98 https://doi.org/10.1021/bi00826a003
99 https://doi.org/10.1021/bi00829a019
100 https://doi.org/10.1021/bi00833a039
101 https://doi.org/10.1021/bi00854a032
102 https://doi.org/10.1021/bi00869a020
103 https://doi.org/10.1021/bi00876a049
104 https://doi.org/10.1021/bi00882a021
105 https://doi.org/10.1021/bi00885a018
106 https://doi.org/10.1021/bi00911a022
107 https://doi.org/10.1021/ed044p84
108 https://doi.org/10.1021/ja00768a029
109 https://doi.org/10.1021/ja00786a054
110 https://doi.org/10.1021/ja00872a023
111 https://doi.org/10.1021/ja00965a060
112 https://doi.org/10.1021/ja00976a034
113 https://doi.org/10.1021/ja01059a049
114 https://doi.org/10.1021/ja01072a015
115 https://doi.org/10.1021/ja01079a027
116 https://doi.org/10.1021/ja01492a058
117 https://doi.org/10.1021/jo00979a005
118 https://doi.org/10.1039/p29720000272
119 https://doi.org/10.1042/bj1010056
120 https://doi.org/10.1042/bj1170333
121 https://doi.org/10.1042/bj1170341
122 https://doi.org/10.1042/bj1260645
123 https://doi.org/10.1042/bj1260659
124 https://doi.org/10.1042/bj1470411
125 https://doi.org/10.1042/bj1930819
126 https://doi.org/10.1073/pnas.50.5.931
127 https://doi.org/10.1073/pnas.56.5.1606
128 https://doi.org/10.1073/pnas.59.3.996
129 https://doi.org/10.1073/pnas.64.4.1335
130 https://doi.org/10.1073/pnas.65.4.1120
131 https://doi.org/10.1073/pnas.68.2.478
132 https://doi.org/10.1073/pnas.70.2.517
133 https://doi.org/10.1073/pnas.70.4.1132
134 https://doi.org/10.1093/oxfordjournals.jbchem.a126856
135 https://doi.org/10.1093/oxfordjournals.jbchem.a126894
136 https://doi.org/10.1093/oxfordjournals.jbchem.a126948
137 https://doi.org/10.1093/oxfordjournals.jbchem.a130158
138 https://doi.org/10.1093/oxfordjournals.jbchem.a130251
139 https://doi.org/10.1093/oxfordjournals.jbchem.a130292
140 https://doi.org/10.1093/oxfordjournals.jbchem.a130311
141 https://doi.org/10.1093/oxfordjournals.jbchem.a130777
142 https://doi.org/10.1093/oxfordjournals.jbchem.a130799
143 https://doi.org/10.1093/oxfordjournals.jbchem.a130947
144 https://doi.org/10.1093/oxfordjournals.jbchem.a131036
145 https://doi.org/10.1093/oxfordjournals.jbchem.a131303
146 https://doi.org/10.1093/oxfordjournals.jbchem.a131580
147 https://doi.org/10.1093/oxfordjournals.jbchem.a131660
148 https://doi.org/10.1093/oxfordjournals.jbchem.a131800
149 https://doi.org/10.1093/oxfordjournals.jbchem.a132157
150 https://doi.org/10.1093/oxfordjournals.jbchem.a132236
151 https://doi.org/10.1093/oxfordjournals.jbchem.a132555
152 https://doi.org/10.1111/j.1399-3011.1972.tb03394.x
153 https://doi.org/10.1111/j.1432-1033.1971.tb01589.x
154 https://doi.org/10.1111/j.1432-1033.1972.tb01754.x
155 https://doi.org/10.1111/j.1432-1033.1973.tb03140.x
156 https://doi.org/10.1111/j.1432-1033.1976.tb11146.x
157 https://doi.org/10.1111/j.1432-1033.1977.tb11832.x
158 https://doi.org/10.1111/j.1432-1033.1979.tb04269.x
159 https://doi.org/10.1139/m64-122
160 https://doi.org/10.1139/o59-157
161 https://doi.org/10.1139/o69-155
162 https://doi.org/10.1146/annurev.bi.34.070165.000405
163 https://doi.org/10.1271/bbb1961.40.1479
164 https://doi.org/10.1515/bchm2.1972.353.2.1646
165 https://doi.org/10.1515/bchm2.1980.361.2.1841
166 https://doi.org/10.3891/acta.chem.scand.08-0356
167 schema:datePublished 1983-03
168 schema:datePublishedReg 1983-03-01
169 schema:description Subtilisin is a bacterial serine protease with a broad specificity in the S1 subsite. It has been very extensively studied using a variety of kinetic and physical techniques. A chemical derivative, thiolsubtilisin, has been subjected to similar studies in order to analyze the effects of the OH to SH conversion on enzyme activity. The native structure of thiolsubtilisin is indicated by a variety of physical techniques. Oligopeptides bind nearly equally well to both enzymes, and a peptide chloromethylketone is much more reactive to thiolsubtilisin than to subtilisin. Both enzymes have a similar level of activity towards activated nonspecific amides and esters. However, thiolsubtilisin is inactive towards highly specific peptide amides and esters. Thiolsubtilisin also does not show good binding to boronic and arsonic acids. The observation that these transition state analog inhibitors bind poorly to thiolsubtilisin while other compounds bind nearly equally well to both enzymes suggests that thiolsubtilisin may not be able to stabilize the transition state during acylation by specific substrates.
170 schema:genre research_article
171 schema:inLanguage en
172 schema:isAccessibleForFree false
173 schema:isPartOf Ncbbc1efdef8c4fdfadd18e971b4f83ee
174 Nf40bf674d5fa473da980c12702d0f5b0
175 sg:journal.1016672
176 schema:name Kinetics of subtilisin and thiolsubtilisin
177 schema:pagination 5-32
178 schema:productId N373aa262a5214d94b96d4b1ea3e1fff7
179 N484d03a9e7284937b3ea0d9e10d2181c
180 N57e2e62663914be798a8fd758a7a48a4
181 Nae8caaa977344dff988424f81196b319
182 Nfde88ee4ebda411e93f22dff6890369d
183 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020119678
184 https://doi.org/10.1007/bf00215583
185 schema:sdDatePublished 2019-04-15T08:58
186 schema:sdLicense https://scigraph.springernature.com/explorer/license/
187 schema:sdPublisher Nbccc3f9b23124c01829d853cc39697db
188 schema:url http://link.springer.com/10.1007/BF00215583
189 sgo:license sg:explorer/license/
190 sgo:sdDataset articles
191 rdf:type schema:ScholarlyArticle
192 N0e8e6b5118834c3b823a319dd44b8692 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
193 schema:name Substrate Specificity
194 rdf:type schema:DefinedTerm
195 N373aa262a5214d94b96d4b1ea3e1fff7 schema:name dimensions_id
196 schema:value pub.1020119678
197 rdf:type schema:PropertyValue
198 N47cb90a4571c4bdaac8eb949ae2f0d9a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
199 schema:name Animals
200 rdf:type schema:DefinedTerm
201 N484d03a9e7284937b3ea0d9e10d2181c schema:name readcube_id
202 schema:value 5fdcef725185653f39fa74da3c0a5683a29b781460d5ec69c8e8f59258e7c8c3
203 rdf:type schema:PropertyValue
204 N57e2e62663914be798a8fd758a7a48a4 schema:name pubmed_id
205 schema:value 6343835
206 rdf:type schema:PropertyValue
207 N742d16d3391645b9831854324a8b6287 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
208 schema:name Subtilisins
209 rdf:type schema:DefinedTerm
210 N91a5e0f91e6c4d0b95f455c15f9d91ef schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
211 schema:name Kinetics
212 rdf:type schema:DefinedTerm
213 N9c7b3e12247e4cffa1a8b72b0adeca08 schema:name Dept. of Chemistry, Lehman College of the City University of New York, and Dept. of Biochemistry, Graduate Center of CUNY, 60201, Evanston, IL, U.S.A.
214 rdf:type schema:Organization
215 Na210fd11c15b4ce3b7a86b27c740559c rdf:first sg:person.01000541074.97
216 rdf:rest Nf0baa17724e34f9dac0ac47587d5f3d3
217 Nac25b148a9ca4b5bb8ad57439faaff97 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
218 schema:name Amides
219 rdf:type schema:DefinedTerm
220 Nae8caaa977344dff988424f81196b319 schema:name doi
221 schema:value 10.1007/bf00215583
222 rdf:type schema:PropertyValue
223 Nbccc3f9b23124c01829d853cc39697db schema:name Springer Nature - SN SciGraph project
224 rdf:type schema:Organization
225 Ncbbc1efdef8c4fdfadd18e971b4f83ee schema:issueNumber 1
226 rdf:type schema:PublicationIssue
227 Nd7b4c46aa1224ab68d937377c2e45a87 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
228 schema:name Acylation
229 rdf:type schema:DefinedTerm
230 Nf0baa17724e34f9dac0ac47587d5f3d3 rdf:first sg:person.0104401344.68
231 rdf:rest rdf:nil
232 Nf40bf674d5fa473da980c12702d0f5b0 schema:volumeNumber 51
233 rdf:type schema:PublicationVolume
234 Nf93d494e1baa4df088cd38a2c7069cc4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
235 schema:name Imidazoles
236 rdf:type schema:DefinedTerm
237 Nfde88ee4ebda411e93f22dff6890369d schema:name nlm_unique_id
238 schema:value 0364456
239 rdf:type schema:PropertyValue
240 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
241 schema:name Chemical Sciences
242 rdf:type schema:DefinedTerm
243 anzsrc-for:0302 schema:inDefinedTermSet anzsrc-for:
244 schema:name Inorganic Chemistry
245 rdf:type schema:DefinedTerm
246 sg:grant.2381527 http://pending.schema.org/fundedItem sg:pub.10.1007/bf00215583
247 rdf:type schema:MonetaryGrant
248 sg:journal.1016672 schema:issn 0300-8177
249 1573-4919
250 schema:name Molecular and Cellular Biochemistry
251 rdf:type schema:Periodical
252 sg:person.01000541074.97 schema:affiliation N9c7b3e12247e4cffa1a8b72b0adeca08
253 schema:familyName Philipp
254 schema:givenName M.
255 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01000541074.97
256 rdf:type schema:Person
257 sg:person.0104401344.68 schema:affiliation https://www.grid.ac/institutes/grid.16753.36
258 schema:familyName Bender
259 schema:givenName M. L.
260 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0104401344.68
261 rdf:type schema:Person
262 sg:pub.10.1007/978-3-642-87966-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001430690
263 https://doi.org/10.1007/978-3-642-87966-1
264 rdf:type schema:CreativeWork
265 sg:pub.10.1007/978-3-642-87966-1_66 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004867027
266 https://doi.org/10.1007/978-3-642-87966-1_66
267 rdf:type schema:CreativeWork
268 sg:pub.10.1007/bf01384275 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039915656
269 https://doi.org/10.1007/bf01384275
270 rdf:type schema:CreativeWork
271 sg:pub.10.1007/bf02906260 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011822303
272 https://doi.org/10.1007/bf02906260
273 rdf:type schema:CreativeWork
274 sg:pub.10.1038/277447a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020540384
275 https://doi.org/10.1038/277447a0
276 rdf:type schema:CreativeWork
277 sg:pub.10.1038/newbio241044a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037749760
278 https://doi.org/10.1038/newbio241044a0
279 rdf:type schema:CreativeWork
280 https://app.dimensions.ai/details/publication/pub.1074932665 schema:CreativeWork
281 https://app.dimensions.ai/details/publication/pub.1075205893 schema:CreativeWork
282 https://app.dimensions.ai/details/publication/pub.1075525105 schema:CreativeWork
283 https://app.dimensions.ai/details/publication/pub.1075795792 schema:CreativeWork
284 https://app.dimensions.ai/details/publication/pub.1075969784 schema:CreativeWork
285 https://app.dimensions.ai/details/publication/pub.1076611542 schema:CreativeWork
286 https://app.dimensions.ai/details/publication/pub.1078443435 schema:CreativeWork
287 https://app.dimensions.ai/details/publication/pub.1078793682 schema:CreativeWork
288 https://app.dimensions.ai/details/publication/pub.1079085234 schema:CreativeWork
289 https://app.dimensions.ai/details/publication/pub.1080519462 schema:CreativeWork
290 https://app.dimensions.ai/details/publication/pub.1080611940 schema:CreativeWork
291 https://app.dimensions.ai/details/publication/pub.1080711661 schema:CreativeWork
292 https://app.dimensions.ai/details/publication/pub.1080713970 schema:CreativeWork
293 https://app.dimensions.ai/details/publication/pub.1080714763 schema:CreativeWork
294 https://app.dimensions.ai/details/publication/pub.1080716869 schema:CreativeWork
295 https://app.dimensions.ai/details/publication/pub.1080720473 schema:CreativeWork
296 https://app.dimensions.ai/details/publication/pub.1080721294 schema:CreativeWork
297 https://app.dimensions.ai/details/publication/pub.1080723340 schema:CreativeWork
298 https://app.dimensions.ai/details/publication/pub.1080723716 schema:CreativeWork
299 https://app.dimensions.ai/details/publication/pub.1080727910 schema:CreativeWork
300 https://app.dimensions.ai/details/publication/pub.1080731835 schema:CreativeWork
301 https://app.dimensions.ai/details/publication/pub.1081007329 schema:CreativeWork
302 https://app.dimensions.ai/details/publication/pub.1081247499 schema:CreativeWork
303 https://app.dimensions.ai/details/publication/pub.1081275765 schema:CreativeWork
304 https://app.dimensions.ai/details/publication/pub.1081549534 schema:CreativeWork
305 https://app.dimensions.ai/details/publication/pub.1081957980 schema:CreativeWork
306 https://app.dimensions.ai/details/publication/pub.1082025656 schema:CreativeWork
307 https://doi.org/10.1002/9780470122709.ch1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047336202
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1002/bit.260171208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009280678
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1002/ijch.197400039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016820404
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1016/0003-9861(66)90073-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027366167
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1016/0003-9861(69)90223-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052034462
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1016/0003-9861(70)90376-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049687326
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1016/0003-9861(70)90377-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011129418
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1016/0003-9861(71)90362-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026309453
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1016/0003-9861(74)90143-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050400824
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1016/0003-9861(75)90310-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011752684
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1016/0003-9861(77)90183-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044328649
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1016/0005-2744(72)90248-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000233710
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1016/0005-2744(73)90207-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053003135
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1016/0005-2744(76)90171-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004638419
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1016/0005-2744(77)90338-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011879647
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1016/0005-2744(78)90178-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1035339591
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1016/0005-2744(78)90238-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035421356
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1016/0005-2744(78)90335-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042734786
342 rdf:type schema:CreativeWork
343 https://doi.org/10.1016/0005-2795(81)90201-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029078692
344 rdf:type schema:CreativeWork
345 https://doi.org/10.1016/0006-291x(69)90269-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042778413
346 rdf:type schema:CreativeWork
347 https://doi.org/10.1016/0006-291x(71)90002-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019588878
348 rdf:type schema:CreativeWork
349 https://doi.org/10.1016/0006-291x(71)90107-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002775441
350 rdf:type schema:CreativeWork
351 https://doi.org/10.1016/0006-291x(75)90860-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040698808
352 rdf:type schema:CreativeWork
353 https://doi.org/10.1016/0006-291x(76)91133-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005231584
354 rdf:type schema:CreativeWork
355 https://doi.org/10.1016/0006-3002(55)90280-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052131120
356 rdf:type schema:CreativeWork
357 https://doi.org/10.1016/0014-5793(73)80629-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015286584
358 rdf:type schema:CreativeWork
359 https://doi.org/10.1016/0014-5793(73)80824-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039138990
360 rdf:type schema:CreativeWork
361 https://doi.org/10.1016/0014-5793(74)80746-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031919644
362 rdf:type schema:CreativeWork
363 https://doi.org/10.1016/0014-5793(77)80754-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015243925
364 rdf:type schema:CreativeWork
365 https://doi.org/10.1016/0014-5793(78)80763-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010200131
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1016/0014-5793(81)80465-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009892541
368 rdf:type schema:CreativeWork
369 https://doi.org/10.1016/0022-2836(72)90391-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027664796
370 rdf:type schema:CreativeWork
371 https://doi.org/10.1016/0022-2836(72)90479-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005462235
372 rdf:type schema:CreativeWork
373 https://doi.org/10.1016/0022-2836(74)90179-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020812897
374 rdf:type schema:CreativeWork
375 https://doi.org/10.1016/0022-2836(79)90205-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047331759
376 rdf:type schema:CreativeWork
377 https://doi.org/10.1016/0031-9422(80)85105-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020113751
378 rdf:type schema:CreativeWork
379 https://doi.org/10.1016/0304-4165(66)90137-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052287479
380 rdf:type schema:CreativeWork
381 https://doi.org/10.1016/0305-0491(72)90319-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016673931
382 rdf:type schema:CreativeWork
383 https://doi.org/10.1016/0305-0491(74)90132-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039364719
384 rdf:type schema:CreativeWork
385 https://doi.org/10.1016/b978-0-12-211850-0.50019-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033425101
386 rdf:type schema:CreativeWork
387 https://doi.org/10.1016/s0003-9861(71)80067-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033288193
388 rdf:type schema:CreativeWork
389 https://doi.org/10.1016/s0006-291x(67)80055-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1042897284
390 rdf:type schema:CreativeWork
391 https://doi.org/10.1021/bi00525a013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055179447
392 rdf:type schema:CreativeWork
393 https://doi.org/10.1021/bi00572a030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055181226
394 rdf:type schema:CreativeWork
395 https://doi.org/10.1021/bi00584a019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055181671
396 rdf:type schema:CreativeWork
397 https://doi.org/10.1021/bi00584a020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055181672
398 rdf:type schema:CreativeWork
399 https://doi.org/10.1021/bi00627a007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055183182
400 rdf:type schema:CreativeWork
401 https://doi.org/10.1021/bi00699a006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055185701
402 rdf:type schema:CreativeWork
403 https://doi.org/10.1021/bi00712a019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055186140
404 rdf:type schema:CreativeWork
405 https://doi.org/10.1021/bi00729a008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055186664
406 rdf:type schema:CreativeWork
407 https://doi.org/10.1021/bi00738a002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055186935
408 rdf:type schema:CreativeWork
409 https://doi.org/10.1021/bi00763a009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055187777
410 rdf:type schema:CreativeWork
411 https://doi.org/10.1021/bi00773a016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055188062
412 rdf:type schema:CreativeWork
413 https://doi.org/10.1021/bi00789a008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055188555
414 rdf:type schema:CreativeWork
415 https://doi.org/10.1021/bi00826a003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055189638
416 rdf:type schema:CreativeWork
417 https://doi.org/10.1021/bi00829a019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055189732
418 rdf:type schema:CreativeWork
419 https://doi.org/10.1021/bi00833a039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055189985
420 rdf:type schema:CreativeWork
421 https://doi.org/10.1021/bi00854a032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055191167
422 rdf:type schema:CreativeWork
423 https://doi.org/10.1021/bi00869a020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055191827
424 rdf:type schema:CreativeWork
425 https://doi.org/10.1021/bi00876a049 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055192177
426 rdf:type schema:CreativeWork
427 https://doi.org/10.1021/bi00882a021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055192350
428 rdf:type schema:CreativeWork
429 https://doi.org/10.1021/bi00885a018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055192451
430 rdf:type schema:CreativeWork
431 https://doi.org/10.1021/bi00911a022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055193372
432 rdf:type schema:CreativeWork
433 https://doi.org/10.1021/ed044p84 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055444755
434 rdf:type schema:CreativeWork
435 https://doi.org/10.1021/ja00768a029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055746255
436 rdf:type schema:CreativeWork
437 https://doi.org/10.1021/ja00786a054 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055747787
438 rdf:type schema:CreativeWork
439 https://doi.org/10.1021/ja00872a023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055754176
440 rdf:type schema:CreativeWork
441 https://doi.org/10.1021/ja00965a060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055757626
442 rdf:type schema:CreativeWork
443 https://doi.org/10.1021/ja00976a034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055758419
444 rdf:type schema:CreativeWork
445 https://doi.org/10.1021/ja01059a049 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055764927
446 rdf:type schema:CreativeWork
447 https://doi.org/10.1021/ja01072a015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055765868
448 rdf:type schema:CreativeWork
449 https://doi.org/10.1021/ja01079a027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055766585
450 rdf:type schema:CreativeWork
451 https://doi.org/10.1021/ja01492a058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055801549
452 rdf:type schema:CreativeWork
453 https://doi.org/10.1021/jo00979a005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055994201
454 rdf:type schema:CreativeWork
455 https://doi.org/10.1039/p29720000272 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005056398
456 rdf:type schema:CreativeWork
457 https://doi.org/10.1042/bj1010056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005244784
458 rdf:type schema:CreativeWork
459 https://doi.org/10.1042/bj1170333 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040838092
460 rdf:type schema:CreativeWork
461 https://doi.org/10.1042/bj1170341 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017142306
462 rdf:type schema:CreativeWork
463 https://doi.org/10.1042/bj1260645 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001738859
464 rdf:type schema:CreativeWork
465 https://doi.org/10.1042/bj1260659 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028295661
466 rdf:type schema:CreativeWork
467 https://doi.org/10.1042/bj1470411 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015374430
468 rdf:type schema:CreativeWork
469 https://doi.org/10.1042/bj1930819 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014308882
470 rdf:type schema:CreativeWork
471 https://doi.org/10.1073/pnas.50.5.931 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032149936
472 rdf:type schema:CreativeWork
473 https://doi.org/10.1073/pnas.56.5.1606 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027331584
474 rdf:type schema:CreativeWork
475 https://doi.org/10.1073/pnas.59.3.996 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040176994
476 rdf:type schema:CreativeWork
477 https://doi.org/10.1073/pnas.64.4.1335 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024832215
478 rdf:type schema:CreativeWork
479 https://doi.org/10.1073/pnas.65.4.1120 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029523405
480 rdf:type schema:CreativeWork
481 https://doi.org/10.1073/pnas.68.2.478 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053429841
482 rdf:type schema:CreativeWork
483 https://doi.org/10.1073/pnas.70.2.517 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020657463
484 rdf:type schema:CreativeWork
485 https://doi.org/10.1073/pnas.70.4.1132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044007770
486 rdf:type schema:CreativeWork
487 https://doi.org/10.1093/oxfordjournals.jbchem.a126856 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083479695
488 rdf:type schema:CreativeWork
489 https://doi.org/10.1093/oxfordjournals.jbchem.a126894 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083479713
490 rdf:type schema:CreativeWork
491 https://doi.org/10.1093/oxfordjournals.jbchem.a126948 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083479732
492 rdf:type schema:CreativeWork
493 https://doi.org/10.1093/oxfordjournals.jbchem.a130158 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080608223
494 rdf:type schema:CreativeWork
495 https://doi.org/10.1093/oxfordjournals.jbchem.a130251 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080573759
496 rdf:type schema:CreativeWork
497 https://doi.org/10.1093/oxfordjournals.jbchem.a130292 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080575217
498 rdf:type schema:CreativeWork
499 https://doi.org/10.1093/oxfordjournals.jbchem.a130311 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080575226
500 rdf:type schema:CreativeWork
501 https://doi.org/10.1093/oxfordjournals.jbchem.a130777 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078763093
502 rdf:type schema:CreativeWork
503 https://doi.org/10.1093/oxfordjournals.jbchem.a130799 schema:sameAs https://app.dimensions.ai/details/publication/pub.1078763130
504 rdf:type schema:CreativeWork
505 https://doi.org/10.1093/oxfordjournals.jbchem.a130947 schema:sameAs https://app.dimensions.ai/details/publication/pub.1081064275
506 rdf:type schema:CreativeWork
507 https://doi.org/10.1093/oxfordjournals.jbchem.a131036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1082408761
508 rdf:type schema:CreativeWork
509 https://doi.org/10.1093/oxfordjournals.jbchem.a131303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074424389
510 rdf:type schema:CreativeWork
511 https://doi.org/10.1093/oxfordjournals.jbchem.a131580 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077949088
512 rdf:type schema:CreativeWork
513 https://doi.org/10.1093/oxfordjournals.jbchem.a131660 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077900772
514 rdf:type schema:CreativeWork
515 https://doi.org/10.1093/oxfordjournals.jbchem.a131800 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083127081
516 rdf:type schema:CreativeWork
517 https://doi.org/10.1093/oxfordjournals.jbchem.a132157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074399355
518 rdf:type schema:CreativeWork
519 https://doi.org/10.1093/oxfordjournals.jbchem.a132236 schema:sameAs https://app.dimensions.ai/details/publication/pub.1079619135
520 rdf:type schema:CreativeWork
521 https://doi.org/10.1093/oxfordjournals.jbchem.a132555 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080596745
522 rdf:type schema:CreativeWork
523 https://doi.org/10.1111/j.1399-3011.1972.tb03394.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014772912
524 rdf:type schema:CreativeWork
525 https://doi.org/10.1111/j.1432-1033.1971.tb01589.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1007493123
526 rdf:type schema:CreativeWork
527 https://doi.org/10.1111/j.1432-1033.1972.tb01754.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1019632595
528 rdf:type schema:CreativeWork
529 https://doi.org/10.1111/j.1432-1033.1973.tb03140.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1023806024
530 rdf:type schema:CreativeWork
531 https://doi.org/10.1111/j.1432-1033.1976.tb11146.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1002576403
532 rdf:type schema:CreativeWork
533 https://doi.org/10.1111/j.1432-1033.1977.tb11832.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1027376969
534 rdf:type schema:CreativeWork
535 https://doi.org/10.1111/j.1432-1033.1979.tb04269.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1007081526
536 rdf:type schema:CreativeWork
537 https://doi.org/10.1139/m64-122 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018213569
538 rdf:type schema:CreativeWork
539 https://doi.org/10.1139/o59-157 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062892878
540 rdf:type schema:CreativeWork
541 https://doi.org/10.1139/o69-155 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047480793
542 rdf:type schema:CreativeWork
543 https://doi.org/10.1146/annurev.bi.34.070165.000405 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018203828
544 rdf:type schema:CreativeWork
545 https://doi.org/10.1271/bbb1961.40.1479 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022020464
546 rdf:type schema:CreativeWork
547 https://doi.org/10.1515/bchm2.1972.353.2.1646 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043065836
548 rdf:type schema:CreativeWork
549 https://doi.org/10.1515/bchm2.1980.361.2.1841 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008056228
550 rdf:type schema:CreativeWork
551 https://doi.org/10.3891/acta.chem.scand.08-0356 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071486955
552 rdf:type schema:CreativeWork
553 https://www.grid.ac/institutes/grid.16753.36 schema:alternateName Northwestern University
554 schema:name Depts. of Biochemistry and Chemistry, Northwestern University, 60201, Evanston, IL, U.S.A.
555 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...