Ontology type: schema:ScholarlyArticle
1993-07
AUTHORSF. Fiaccadori, G. Pedretti, G. Pasetti, P. Pizzaferri, G. Elia
ABSTRACTThe effects of long-term therapy (70 days) with torasemide (20 mg/day), a new loop diuretic, were compared with those of furosemide (50 mg/day) in a randomized double-blind trial. Both drugs were administered in association with spironolactone (200 mg/day) in 28 nonazotemic cirrhotic patients with controlled ascites. The treatments did not modify creatinine clearance and exhibited a similar effect on body weight, urinary volume, and fractional excretion of uric acid, sodium, and chloride. The effect of torasemide on fractional potassium excretion was lower than that of furosemide. Torasemide showed higher sparing effect than furosemide on calcium, inorganic phosphate, and magnesium excretion and stronger action on free water clearance. No changes in serum parameters were induced by either treatment. Two episodes of hepatic encephalopathy occurred in the torasemide group. In view of its effects on sodium and water excretion and on other urinary parameters, torasemide can represent an alternative tool for the long-term treatment of ascites. More... »
PAGES579-584
http://scigraph.springernature.com/pub.10.1007/bf00208486
DOIhttp://dx.doi.org/10.1007/bf00208486
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1042740270
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/8374255
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Clinical Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Ascites",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Diuretics",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Double-Blind Method",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Drug Therapy, Combination",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Furosemide",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Liver Cirrhosis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Spironolactone",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Sulfonamides",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Torsemide",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "University of Parma",
"id": "https://www.grid.ac/institutes/grid.10383.39",
"name": [
"Cattedra di Malattie Infettive, Universita' di Parma, via Gramsci 14, I-43100, Parma, Italy"
],
"type": "Organization"
},
"familyName": "Fiaccadori",
"givenName": "F.",
"id": "sg:person.010722460614.67",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010722460614.67"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Parma",
"id": "https://www.grid.ac/institutes/grid.10383.39",
"name": [
"Cattedra di Malattie Infettive, Universita' di Parma, via Gramsci 14, I-43100, Parma, Italy"
],
"type": "Organization"
},
"familyName": "Pedretti",
"givenName": "G.",
"id": "sg:person.01246052260.36",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246052260.36"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Parma",
"id": "https://www.grid.ac/institutes/grid.10383.39",
"name": [
"Cattedra di Malattie Infettive, Universita' di Parma, via Gramsci 14, I-43100, Parma, Italy"
],
"type": "Organization"
},
"familyName": "Pasetti",
"givenName": "G.",
"id": "sg:person.054704200.60",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.054704200.60"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Parma",
"id": "https://www.grid.ac/institutes/grid.10383.39",
"name": [
"Cattedra di Malattie Infettive, Universita' di Parma, via Gramsci 14, I-43100, Parma, Italy"
],
"type": "Organization"
},
"familyName": "Pizzaferri",
"givenName": "P.",
"id": "sg:person.013337346134.41",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013337346134.41"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "University of Parma",
"id": "https://www.grid.ac/institutes/grid.10383.39",
"name": [
"Cattedra di Malattie Infettive, Universita' di Parma, via Gramsci 14, I-43100, Parma, Italy"
],
"type": "Organization"
},
"familyName": "Elia",
"givenName": "G.",
"id": "sg:person.0660200630.51",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660200630.51"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/bf00541460",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003363483",
"https://doi.org/10.1007/bf00541460"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00541460",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003363483",
"https://doi.org/10.1007/bf00541460"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.2165/00003495-199100413-00003",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017857196",
"https://doi.org/10.2165/00003495-199100413-00003"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00541464",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033162438",
"https://doi.org/10.1007/bf00541464"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00541464",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033162438",
"https://doi.org/10.1007/bf00541464"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ki.1972.3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033649920",
"https://doi.org/10.1038/ki.1972.3"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1111/j.1749-6632.1966.tb41207.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041679331"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/hep.1840130616",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047051736"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0002-9343(69)90187-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050813268"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079662548",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079662549",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079662552",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079662553",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079708566",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079708569",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081687492",
"type": "CreativeWork"
}
],
"datePublished": "1993-07",
"datePublishedReg": "1993-07-01",
"description": "The effects of long-term therapy (70 days) with torasemide (20 mg/day), a new loop diuretic, were compared with those of furosemide (50 mg/day) in a randomized double-blind trial. Both drugs were administered in association with spironolactone (200 mg/day) in 28 nonazotemic cirrhotic patients with controlled ascites. The treatments did not modify creatinine clearance and exhibited a similar effect on body weight, urinary volume, and fractional excretion of uric acid, sodium, and chloride. The effect of torasemide on fractional potassium excretion was lower than that of furosemide. Torasemide showed higher sparing effect than furosemide on calcium, inorganic phosphate, and magnesium excretion and stronger action on free water clearance. No changes in serum parameters were induced by either treatment. Two episodes of hepatic encephalopathy occurred in the torasemide group. In view of its effects on sodium and water excretion and on other urinary parameters, torasemide can represent an alternative tool for the long-term treatment of ascites.",
"genre": "research_article",
"id": "sg:pub.10.1007/bf00208486",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1057918",
"issn": [
"0946-2716",
"1432-1440"
],
"name": "Journal of Molecular Medicine",
"type": "Periodical"
},
{
"issueNumber": "7",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "71"
}
],
"name": "Torasemide versus furosemide in cirrhosis: a long-term, double-blind, randomized clinical study",
"pagination": "579-584",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"cb970a5e08b27007144cd70c51278c44688d0ac2bb3b07fb3e435d679ebaf808"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"8374255"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"9207154"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1007/bf00208486"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1042740270"
]
}
],
"sameAs": [
"https://doi.org/10.1007/bf00208486",
"https://app.dimensions.ai/details/publication/pub.1042740270"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T13:49",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000371_0000000371/records_130794_00000003.jsonl",
"type": "ScholarlyArticle",
"url": "http://link.springer.com/10.1007/BF00208486"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00208486'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00208486'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00208486'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00208486'
This table displays all metadata directly associated to this object as RDF triples.
176 TRIPLES
21 PREDICATES
53 URIs
31 LITERALS
19 BLANK NODES