The value of thallium and three-phase bone scans in the evaluation of bone and soft tissue sarcomas View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1994-11

AUTHORS

Calin I. Caluser, Hussein M. Abdel-Dayem, Homer A. Macapinlac, Andrew Scott, John H. Healey, Andrew Huvos, Hovanes Kalaigian, Samuel D. J. Yeh, Steven M. Larson

ABSTRACT

Thirty-seven patients with newly diagnosed or treated sarcomas had 47 sets of sequential thallium scans (TS) followed by three-phase bone scan (TPBS) on the same day. The diagnosis in all patients was verified by biopsy (n = 40) or long-term follow-up studies (n = 7). The sensitivity, specificity, and accuracy of TS and TPBS in detecting sarcomatous lesions was calculated: TS sensitivity was 88%, specificity 69%, and accuracy 83%; blood flow (BF) and blood pool (BP) sensitivity was 91%, specificity 54%, and accuracy 81%; delayed bone scan (DB) sensitivity was 88%, specificity 38%, and accuracy 74%. In 17 studies the flow and blood pool parts of the TPBS and TS demonstrated the soft tissue component of sarcomas, which would have been missed if only the delayed bone scan had been performed. The TS lesion to normal tissue ratio alone was not very helpful in differentiating sarcomas from benign conditions because some benign lesions are highly cellular and vascular while some malignant lesions, such as chondrosarcoma, have poor vascularity and a less cellular chondroid matrix. However, when the thallium ratio was correlated with similar ratios calculated from the BP image, it was found that if the TS lesion to normal tissue ratio exceeded the BP lesion to normal tissue ratio (12 patients), the specificity for detecting sarcomatous lesions was 100%. Nevertheless, the reverse was not true. The positive predictive value of this observation was 100% and the negative predictive value was 37%. More... »

PAGES

1198-1205

References to SciGraph publications

  • 1989-07. Mechanism of 201Tl uptake in tumours in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 1988-01. The optimum time for tumour imaging with thallium-201 in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 1987-02. Biodistributions of 201Tl in tumor bearing animals and inflammatory lesion induced animals in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/bf00182353

    DOI

    http://dx.doi.org/10.1007/bf00182353

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1012971230

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/7859771


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1103", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Clinical Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adolescent", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adult", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Bone Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Bone and Bones", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Child", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Chondrosarcoma", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Evaluation Studies as Topic", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Female", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Male", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Middle Aged", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Osteosarcoma", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Predictive Value of Tests", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Radionuclide Imaging", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Sarcoma", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Sensitivity and Specificity", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Soft Tissue Neoplasms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Technetium Tc 99m Medronate", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Thallium Radioisotopes", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Memorial Sloan Kettering Cancer Center", 
              "id": "https://www.grid.ac/institutes/grid.51462.34", 
              "name": [
                "Nuclear Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Caluser", 
            "givenName": "Calin I.", 
            "id": "sg:person.01354675430.68", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354675430.68"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Memorial Sloan Kettering Cancer Center", 
              "id": "https://www.grid.ac/institutes/grid.51462.34", 
              "name": [
                "Nuclear Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Abdel-Dayem", 
            "givenName": "Hussein M.", 
            "id": "sg:person.0760504415.54", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0760504415.54"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Memorial Sloan Kettering Cancer Center", 
              "id": "https://www.grid.ac/institutes/grid.51462.34", 
              "name": [
                "Nuclear Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Macapinlac", 
            "givenName": "Homer A.", 
            "id": "sg:person.0677650210.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677650210.40"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Memorial Sloan Kettering Cancer Center", 
              "id": "https://www.grid.ac/institutes/grid.51462.34", 
              "name": [
                "Nuclear Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Scott", 
            "givenName": "Andrew", 
            "id": "sg:person.010717270007.67", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010717270007.67"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Memorial Sloan Kettering Cancer Center", 
              "id": "https://www.grid.ac/institutes/grid.51462.34", 
              "name": [
                "Orthopaedic Surgery Service, Memorial Sloan Kettering Cancer Center, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Healey", 
            "givenName": "John H.", 
            "id": "sg:person.0636537022.89", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636537022.89"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Memorial Sloan Kettering Cancer Center", 
              "id": "https://www.grid.ac/institutes/grid.51462.34", 
              "name": [
                "Pathology Department, Memorial Sloan Kettering Cancer Center, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Huvos", 
            "givenName": "Andrew", 
            "id": "sg:person.0661101406.39", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661101406.39"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Memorial Sloan Kettering Cancer Center", 
              "id": "https://www.grid.ac/institutes/grid.51462.34", 
              "name": [
                "Nuclear Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kalaigian", 
            "givenName": "Hovanes", 
            "id": "sg:person.01173751720.00", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173751720.00"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Memorial Sloan Kettering Cancer Center", 
              "id": "https://www.grid.ac/institutes/grid.51462.34", 
              "name": [
                "Nuclear Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Yeh", 
            "givenName": "Samuel D. J.", 
            "id": "sg:person.011240656512.96", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011240656512.96"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Memorial Sloan Kettering Cancer Center", 
              "id": "https://www.grid.ac/institutes/grid.51462.34", 
              "name": [
                "Nuclear Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Larson", 
            "givenName": "Steven M.", 
            "id": "sg:person.013306534017.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013306534017.05"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1007/bf00256629", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002438156", 
              "https://doi.org/10.1007/bf00256629"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00256629", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002438156", 
              "https://doi.org/10.1007/bf00256629"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-199207000-00007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004431309"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-199207000-00007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004431309"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/bjs.1800700903", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010214141"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1097-0142(19820315)49:6<1221::aid-cncr2820490625>3.0.co;2-e", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012701975"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1097-0142(19840201)53:3<577::aid-cncr2820530335>3.0.co;2-u", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014257454"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-198803000-00003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015716062"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-198803000-00003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015716062"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1097-0142(19810501)47:9<2204::aid-cncr2820470916>3.0.co;2-a", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016710416"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0001-2998(78)80019-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016724349"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1097-0142(19810901)48:5<1133::aid-cncr2820480515>3.0.co;2-h", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016810463"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-199209000-00020", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019833995"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-199209000-00020", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019833995"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-198209000-00001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025956414"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-198209000-00001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025956414"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-198803000-00024", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027219530"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-198803000-00024", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027219530"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00449228", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029047089", 
              "https://doi.org/10.1007/bf00449228"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00449228", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029047089", 
              "https://doi.org/10.1007/bf00449228"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-197703000-00001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033980336"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00003072-197703000-00001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033980336"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00006231-198907000-00004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035397989"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00006231-198907000-00004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035397989"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1378/chest.93.3.672", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037594763"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00296099", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038640196", 
              "https://doi.org/10.1007/bf00296099"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00296099", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038640196", 
              "https://doi.org/10.1007/bf00296099"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0005-2744(68)90254-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046907186"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0005-2744(68)90254-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046907186"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1259/0007-1285-49-585-767", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064551108"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2106/00004623-198163020-00011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068887533"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2214/ajr.134.2.303", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069310307"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2214/ajr.142.4.773", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069312565"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078031599", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078402391", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1078691343", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1079766564", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1148/radiology.146.2.6294738", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1081665939"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1148/121.2.487", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1083347837"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1994-11", 
        "datePublishedReg": "1994-11-01", 
        "description": "Thirty-seven patients with newly diagnosed or treated sarcomas had 47 sets of sequential thallium scans (TS) followed by three-phase bone scan (TPBS) on the same day. The diagnosis in all patients was verified by biopsy (n = 40) or long-term follow-up studies (n = 7). The sensitivity, specificity, and accuracy of TS and TPBS in detecting sarcomatous lesions was calculated: TS sensitivity was 88%, specificity 69%, and accuracy 83%; blood flow (BF) and blood pool (BP) sensitivity was 91%, specificity 54%, and accuracy 81%; delayed bone scan (DB) sensitivity was 88%, specificity 38%, and accuracy 74%. In 17 studies the flow and blood pool parts of the TPBS and TS demonstrated the soft tissue component of sarcomas, which would have been missed if only the delayed bone scan had been performed. The TS lesion to normal tissue ratio alone was not very helpful in differentiating sarcomas from benign conditions because some benign lesions are highly cellular and vascular while some malignant lesions, such as chondrosarcoma, have poor vascularity and a less cellular chondroid matrix. However, when the thallium ratio was correlated with similar ratios calculated from the BP image, it was found that if the TS lesion to normal tissue ratio exceeded the BP lesion to normal tissue ratio (12 patients), the specificity for detecting sarcomatous lesions was 100%. Nevertheless, the reverse was not true. The positive predictive value of this observation was 100% and the negative predictive value was 37%.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1007/bf00182353", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1297401", 
            "issn": [
              "1619-7070", 
              "1619-7089"
            ], 
            "name": "European Journal of Nuclear Medicine and Molecular Imaging", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "11", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "21"
          }
        ], 
        "name": "The value of thallium and three-phase bone scans in the evaluation of bone and soft tissue sarcomas", 
        "pagination": "1198-1205", 
        "productId": [
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/bf00182353"
            ]
          }, 
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "3dcbde4166f7bc6da2ff6b84b8d47a23f1d421ce1eebe07ff72a849270f99b51"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1012971230"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "7606882"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "7859771"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1007/bf00182353", 
          "https://app.dimensions.ai/details/publication/pub.1012971230"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-15T09:02", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000375_0000000375/records_91453_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://link.springer.com/10.1007/BF00182353"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/bf00182353'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00182353'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00182353'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00182353'


     

    This table displays all metadata directly associated to this object as RDF triples.

    290 TRIPLES      21 PREDICATES      77 URIs      41 LITERALS      29 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/bf00182353 schema:about N0207197040204127b8dc07d40537615d
    2 N101e04422eaa4789a190df14529cce36
    3 N1150ed13423e4035b24db9c4f0cc5585
    4 N357677f172714808ab8214752fea0d71
    5 N3e4cee11989b4a9188a8136953b59119
    6 N6421ad76e6354daf9ba71e444d2dcd3a
    7 N6ff13fecac6643ac8156363bd35d098b
    8 N71ecec347a204e07b3094ea954ecb667
    9 N7b5341b884474ccc8b496ff94cd956dc
    10 N97fd394f0296460b9334565216eb567f
    11 N9f59dc15c74349b1817bb8aacf047fbd
    12 Nb2ff0de69ff24adca5f671155a94b064
    13 Nb5f5b76913834530b1db0a8222cd4b40
    14 Nb8a894ada013492ea8da3d0caab5ef32
    15 Nbd7863e8aa434ab5922ca54cd74a9013
    16 Nbdbca17b13bc47e4885f70c3bbea432a
    17 Nd08bb2f6ddb04bb5a36e3a55d947b522
    18 Ndc806652e1e54a57acb373d76d47de2b
    19 Nddf7a1273c6649cabb4410f352b16e3f
    20 Nf9cf2280863b4ac3b59877a34dafc078
    21 anzsrc-for:11
    22 anzsrc-for:1103
    23 schema:author Ndbff815693ae44deaaac65d86d195f70
    24 schema:citation sg:pub.10.1007/bf00256629
    25 sg:pub.10.1007/bf00296099
    26 sg:pub.10.1007/bf00449228
    27 https://app.dimensions.ai/details/publication/pub.1078031599
    28 https://app.dimensions.ai/details/publication/pub.1078402391
    29 https://app.dimensions.ai/details/publication/pub.1078691343
    30 https://app.dimensions.ai/details/publication/pub.1079766564
    31 https://doi.org/10.1002/1097-0142(19810501)47:9<2204::aid-cncr2820470916>3.0.co;2-a
    32 https://doi.org/10.1002/1097-0142(19810901)48:5<1133::aid-cncr2820480515>3.0.co;2-h
    33 https://doi.org/10.1002/1097-0142(19820315)49:6<1221::aid-cncr2820490625>3.0.co;2-e
    34 https://doi.org/10.1002/1097-0142(19840201)53:3<577::aid-cncr2820530335>3.0.co;2-u
    35 https://doi.org/10.1002/bjs.1800700903
    36 https://doi.org/10.1016/0005-2744(68)90254-4
    37 https://doi.org/10.1016/s0001-2998(78)80019-1
    38 https://doi.org/10.1097/00003072-197703000-00001
    39 https://doi.org/10.1097/00003072-198209000-00001
    40 https://doi.org/10.1097/00003072-198803000-00003
    41 https://doi.org/10.1097/00003072-198803000-00024
    42 https://doi.org/10.1097/00003072-199207000-00007
    43 https://doi.org/10.1097/00003072-199209000-00020
    44 https://doi.org/10.1097/00006231-198907000-00004
    45 https://doi.org/10.1148/121.2.487
    46 https://doi.org/10.1148/radiology.146.2.6294738
    47 https://doi.org/10.1259/0007-1285-49-585-767
    48 https://doi.org/10.1378/chest.93.3.672
    49 https://doi.org/10.2106/00004623-198163020-00011
    50 https://doi.org/10.2214/ajr.134.2.303
    51 https://doi.org/10.2214/ajr.142.4.773
    52 schema:datePublished 1994-11
    53 schema:datePublishedReg 1994-11-01
    54 schema:description Thirty-seven patients with newly diagnosed or treated sarcomas had 47 sets of sequential thallium scans (TS) followed by three-phase bone scan (TPBS) on the same day. The diagnosis in all patients was verified by biopsy (n = 40) or long-term follow-up studies (n = 7). The sensitivity, specificity, and accuracy of TS and TPBS in detecting sarcomatous lesions was calculated: TS sensitivity was 88%, specificity 69%, and accuracy 83%; blood flow (BF) and blood pool (BP) sensitivity was 91%, specificity 54%, and accuracy 81%; delayed bone scan (DB) sensitivity was 88%, specificity 38%, and accuracy 74%. In 17 studies the flow and blood pool parts of the TPBS and TS demonstrated the soft tissue component of sarcomas, which would have been missed if only the delayed bone scan had been performed. The TS lesion to normal tissue ratio alone was not very helpful in differentiating sarcomas from benign conditions because some benign lesions are highly cellular and vascular while some malignant lesions, such as chondrosarcoma, have poor vascularity and a less cellular chondroid matrix. However, when the thallium ratio was correlated with similar ratios calculated from the BP image, it was found that if the TS lesion to normal tissue ratio exceeded the BP lesion to normal tissue ratio (12 patients), the specificity for detecting sarcomatous lesions was 100%. Nevertheless, the reverse was not true. The positive predictive value of this observation was 100% and the negative predictive value was 37%.
    55 schema:genre research_article
    56 schema:inLanguage en
    57 schema:isAccessibleForFree false
    58 schema:isPartOf N3f1f2eab875b456c8f1a794594a0d5fa
    59 Nf69f32bc9b634e2d8ae869f625bae671
    60 sg:journal.1297401
    61 schema:name The value of thallium and three-phase bone scans in the evaluation of bone and soft tissue sarcomas
    62 schema:pagination 1198-1205
    63 schema:productId N25d0fdec45934dcd9d0e5cc7e40330bb
    64 N585317db70e44efdace12a4db15cd0ba
    65 N907302c080e84f6bb940c99579b1e269
    66 N914a856116f44571b58c63731be40ec7
    67 Nd820bb7aff7a4e5592f28a4eb1770d22
    68 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012971230
    69 https://doi.org/10.1007/bf00182353
    70 schema:sdDatePublished 2019-04-15T09:02
    71 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    72 schema:sdPublisher Nebeb2cf186a94b2995521e46f7ba4ac5
    73 schema:url http://link.springer.com/10.1007/BF00182353
    74 sgo:license sg:explorer/license/
    75 sgo:sdDataset articles
    76 rdf:type schema:ScholarlyArticle
    77 N0207197040204127b8dc07d40537615d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    78 schema:name Radionuclide Imaging
    79 rdf:type schema:DefinedTerm
    80 N09f5232e6bf34d118030e98ec5911db8 rdf:first sg:person.0661101406.39
    81 rdf:rest N27e25ce69a7a41a9b709dfb9cc24dfe7
    82 N101e04422eaa4789a190df14529cce36 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    83 schema:name Osteosarcoma
    84 rdf:type schema:DefinedTerm
    85 N1150ed13423e4035b24db9c4f0cc5585 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    86 schema:name Evaluation Studies as Topic
    87 rdf:type schema:DefinedTerm
    88 N25d0fdec45934dcd9d0e5cc7e40330bb schema:name doi
    89 schema:value 10.1007/bf00182353
    90 rdf:type schema:PropertyValue
    91 N27e25ce69a7a41a9b709dfb9cc24dfe7 rdf:first sg:person.01173751720.00
    92 rdf:rest Naf2a54c5f1b140aa8604373728a7b914
    93 N357677f172714808ab8214752fea0d71 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    94 schema:name Sarcoma
    95 rdf:type schema:DefinedTerm
    96 N3e4cee11989b4a9188a8136953b59119 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    97 schema:name Adult
    98 rdf:type schema:DefinedTerm
    99 N3f1f2eab875b456c8f1a794594a0d5fa schema:issueNumber 11
    100 rdf:type schema:PublicationIssue
    101 N49cfb05e7b214d7a9f1ffeafa80ce78b rdf:first sg:person.0636537022.89
    102 rdf:rest N09f5232e6bf34d118030e98ec5911db8
    103 N585317db70e44efdace12a4db15cd0ba schema:name dimensions_id
    104 schema:value pub.1012971230
    105 rdf:type schema:PropertyValue
    106 N6421ad76e6354daf9ba71e444d2dcd3a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    107 schema:name Bone Neoplasms
    108 rdf:type schema:DefinedTerm
    109 N6ff13fecac6643ac8156363bd35d098b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    110 schema:name Female
    111 rdf:type schema:DefinedTerm
    112 N71ecec347a204e07b3094ea954ecb667 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    113 schema:name Sensitivity and Specificity
    114 rdf:type schema:DefinedTerm
    115 N7b5341b884474ccc8b496ff94cd956dc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    116 schema:name Humans
    117 rdf:type schema:DefinedTerm
    118 N80ccaf761b24407698d4344c408f89f3 rdf:first sg:person.010717270007.67
    119 rdf:rest N49cfb05e7b214d7a9f1ffeafa80ce78b
    120 N8ce94f6a24884efdbba8450774a1e75f rdf:first sg:person.0677650210.40
    121 rdf:rest N80ccaf761b24407698d4344c408f89f3
    122 N907302c080e84f6bb940c99579b1e269 schema:name nlm_unique_id
    123 schema:value 7606882
    124 rdf:type schema:PropertyValue
    125 N914a856116f44571b58c63731be40ec7 schema:name readcube_id
    126 schema:value 3dcbde4166f7bc6da2ff6b84b8d47a23f1d421ce1eebe07ff72a849270f99b51
    127 rdf:type schema:PropertyValue
    128 N93edb0023d7e40bf88771ac7695d94a8 rdf:first sg:person.013306534017.05
    129 rdf:rest rdf:nil
    130 N97fd394f0296460b9334565216eb567f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    131 schema:name Soft Tissue Neoplasms
    132 rdf:type schema:DefinedTerm
    133 N9f59dc15c74349b1817bb8aacf047fbd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    134 schema:name Chondrosarcoma
    135 rdf:type schema:DefinedTerm
    136 Na2bd045312dc4fd3b83852fd4319a96a rdf:first sg:person.0760504415.54
    137 rdf:rest N8ce94f6a24884efdbba8450774a1e75f
    138 Naf2a54c5f1b140aa8604373728a7b914 rdf:first sg:person.011240656512.96
    139 rdf:rest N93edb0023d7e40bf88771ac7695d94a8
    140 Nb2ff0de69ff24adca5f671155a94b064 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    141 schema:name Child
    142 rdf:type schema:DefinedTerm
    143 Nb5f5b76913834530b1db0a8222cd4b40 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    144 schema:name Predictive Value of Tests
    145 rdf:type schema:DefinedTerm
    146 Nb8a894ada013492ea8da3d0caab5ef32 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    147 schema:name Thallium Radioisotopes
    148 rdf:type schema:DefinedTerm
    149 Nbd7863e8aa434ab5922ca54cd74a9013 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    150 schema:name Bone and Bones
    151 rdf:type schema:DefinedTerm
    152 Nbdbca17b13bc47e4885f70c3bbea432a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    153 schema:name Male
    154 rdf:type schema:DefinedTerm
    155 Nd08bb2f6ddb04bb5a36e3a55d947b522 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    156 schema:name Adolescent
    157 rdf:type schema:DefinedTerm
    158 Nd820bb7aff7a4e5592f28a4eb1770d22 schema:name pubmed_id
    159 schema:value 7859771
    160 rdf:type schema:PropertyValue
    161 Ndbff815693ae44deaaac65d86d195f70 rdf:first sg:person.01354675430.68
    162 rdf:rest Na2bd045312dc4fd3b83852fd4319a96a
    163 Ndc806652e1e54a57acb373d76d47de2b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    164 schema:name Technetium Tc 99m Medronate
    165 rdf:type schema:DefinedTerm
    166 Nddf7a1273c6649cabb4410f352b16e3f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    167 schema:name Aged
    168 rdf:type schema:DefinedTerm
    169 Nebeb2cf186a94b2995521e46f7ba4ac5 schema:name Springer Nature - SN SciGraph project
    170 rdf:type schema:Organization
    171 Nf69f32bc9b634e2d8ae869f625bae671 schema:volumeNumber 21
    172 rdf:type schema:PublicationVolume
    173 Nf9cf2280863b4ac3b59877a34dafc078 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    174 schema:name Middle Aged
    175 rdf:type schema:DefinedTerm
    176 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    177 schema:name Medical and Health Sciences
    178 rdf:type schema:DefinedTerm
    179 anzsrc-for:1103 schema:inDefinedTermSet anzsrc-for:
    180 schema:name Clinical Sciences
    181 rdf:type schema:DefinedTerm
    182 sg:journal.1297401 schema:issn 1619-7070
    183 1619-7089
    184 schema:name European Journal of Nuclear Medicine and Molecular Imaging
    185 rdf:type schema:Periodical
    186 sg:person.010717270007.67 schema:affiliation https://www.grid.ac/institutes/grid.51462.34
    187 schema:familyName Scott
    188 schema:givenName Andrew
    189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010717270007.67
    190 rdf:type schema:Person
    191 sg:person.011240656512.96 schema:affiliation https://www.grid.ac/institutes/grid.51462.34
    192 schema:familyName Yeh
    193 schema:givenName Samuel D. J.
    194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011240656512.96
    195 rdf:type schema:Person
    196 sg:person.01173751720.00 schema:affiliation https://www.grid.ac/institutes/grid.51462.34
    197 schema:familyName Kalaigian
    198 schema:givenName Hovanes
    199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01173751720.00
    200 rdf:type schema:Person
    201 sg:person.013306534017.05 schema:affiliation https://www.grid.ac/institutes/grid.51462.34
    202 schema:familyName Larson
    203 schema:givenName Steven M.
    204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013306534017.05
    205 rdf:type schema:Person
    206 sg:person.01354675430.68 schema:affiliation https://www.grid.ac/institutes/grid.51462.34
    207 schema:familyName Caluser
    208 schema:givenName Calin I.
    209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01354675430.68
    210 rdf:type schema:Person
    211 sg:person.0636537022.89 schema:affiliation https://www.grid.ac/institutes/grid.51462.34
    212 schema:familyName Healey
    213 schema:givenName John H.
    214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636537022.89
    215 rdf:type schema:Person
    216 sg:person.0661101406.39 schema:affiliation https://www.grid.ac/institutes/grid.51462.34
    217 schema:familyName Huvos
    218 schema:givenName Andrew
    219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0661101406.39
    220 rdf:type schema:Person
    221 sg:person.0677650210.40 schema:affiliation https://www.grid.ac/institutes/grid.51462.34
    222 schema:familyName Macapinlac
    223 schema:givenName Homer A.
    224 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677650210.40
    225 rdf:type schema:Person
    226 sg:person.0760504415.54 schema:affiliation https://www.grid.ac/institutes/grid.51462.34
    227 schema:familyName Abdel-Dayem
    228 schema:givenName Hussein M.
    229 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0760504415.54
    230 rdf:type schema:Person
    231 sg:pub.10.1007/bf00256629 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002438156
    232 https://doi.org/10.1007/bf00256629
    233 rdf:type schema:CreativeWork
    234 sg:pub.10.1007/bf00296099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038640196
    235 https://doi.org/10.1007/bf00296099
    236 rdf:type schema:CreativeWork
    237 sg:pub.10.1007/bf00449228 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029047089
    238 https://doi.org/10.1007/bf00449228
    239 rdf:type schema:CreativeWork
    240 https://app.dimensions.ai/details/publication/pub.1078031599 schema:CreativeWork
    241 https://app.dimensions.ai/details/publication/pub.1078402391 schema:CreativeWork
    242 https://app.dimensions.ai/details/publication/pub.1078691343 schema:CreativeWork
    243 https://app.dimensions.ai/details/publication/pub.1079766564 schema:CreativeWork
    244 https://doi.org/10.1002/1097-0142(19810501)47:9<2204::aid-cncr2820470916>3.0.co;2-a schema:sameAs https://app.dimensions.ai/details/publication/pub.1016710416
    245 rdf:type schema:CreativeWork
    246 https://doi.org/10.1002/1097-0142(19810901)48:5<1133::aid-cncr2820480515>3.0.co;2-h schema:sameAs https://app.dimensions.ai/details/publication/pub.1016810463
    247 rdf:type schema:CreativeWork
    248 https://doi.org/10.1002/1097-0142(19820315)49:6<1221::aid-cncr2820490625>3.0.co;2-e schema:sameAs https://app.dimensions.ai/details/publication/pub.1012701975
    249 rdf:type schema:CreativeWork
    250 https://doi.org/10.1002/1097-0142(19840201)53:3<577::aid-cncr2820530335>3.0.co;2-u schema:sameAs https://app.dimensions.ai/details/publication/pub.1014257454
    251 rdf:type schema:CreativeWork
    252 https://doi.org/10.1002/bjs.1800700903 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010214141
    253 rdf:type schema:CreativeWork
    254 https://doi.org/10.1016/0005-2744(68)90254-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046907186
    255 rdf:type schema:CreativeWork
    256 https://doi.org/10.1016/s0001-2998(78)80019-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016724349
    257 rdf:type schema:CreativeWork
    258 https://doi.org/10.1097/00003072-197703000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033980336
    259 rdf:type schema:CreativeWork
    260 https://doi.org/10.1097/00003072-198209000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025956414
    261 rdf:type schema:CreativeWork
    262 https://doi.org/10.1097/00003072-198803000-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015716062
    263 rdf:type schema:CreativeWork
    264 https://doi.org/10.1097/00003072-198803000-00024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027219530
    265 rdf:type schema:CreativeWork
    266 https://doi.org/10.1097/00003072-199207000-00007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004431309
    267 rdf:type schema:CreativeWork
    268 https://doi.org/10.1097/00003072-199209000-00020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019833995
    269 rdf:type schema:CreativeWork
    270 https://doi.org/10.1097/00006231-198907000-00004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035397989
    271 rdf:type schema:CreativeWork
    272 https://doi.org/10.1148/121.2.487 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083347837
    273 rdf:type schema:CreativeWork
    274 https://doi.org/10.1148/radiology.146.2.6294738 schema:sameAs https://app.dimensions.ai/details/publication/pub.1081665939
    275 rdf:type schema:CreativeWork
    276 https://doi.org/10.1259/0007-1285-49-585-767 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064551108
    277 rdf:type schema:CreativeWork
    278 https://doi.org/10.1378/chest.93.3.672 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037594763
    279 rdf:type schema:CreativeWork
    280 https://doi.org/10.2106/00004623-198163020-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068887533
    281 rdf:type schema:CreativeWork
    282 https://doi.org/10.2214/ajr.134.2.303 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069310307
    283 rdf:type schema:CreativeWork
    284 https://doi.org/10.2214/ajr.142.4.773 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069312565
    285 rdf:type schema:CreativeWork
    286 https://www.grid.ac/institutes/grid.51462.34 schema:alternateName Memorial Sloan Kettering Cancer Center
    287 schema:name Nuclear Medicine Service, Memorial Sloan Kettering Cancer Center, New York, USA
    288 Orthopaedic Surgery Service, Memorial Sloan Kettering Cancer Center, New York, USA
    289 Pathology Department, Memorial Sloan Kettering Cancer Center, New York, USA
    290 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...