Effects of amphetamine on local cerebral metabolism in normal and schizophrenic subjects as determined by positron emission tomography View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1987-06

AUTHORS

A. Wolkin, B. Angrist, A. Wolf, J. Brodie, B. Wolkin, J. Jaeger, R. Cancro, J. Rotrosen

ABSTRACT

The effects of d-amphetamine (0.5 mg/kg PO) on regional cerebral glucose utilization were measured with Positron Emission Tomography (PET). Subjects included ten chronic schizophrenics and six controls who received amphetamine, and six chronic schizophrenics and nine controls who received placebo or no treatment. Amphetamine decreased glucose metabolism in all regions studied (frontal, temporal, and striatal) in normal and schizophrenic subjects. The metabolic effects of amphetamine were correlated with plasma level of the drug. Cortical atrophy was associated with a blunted metabolic response. More... »

PAGES

241-246

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/bf00177923

DOI

http://dx.doi.org/10.1007/bf00177923

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1028037552

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3110848


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curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/bf00177923'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/bf00177923'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/bf00177923'


 

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